Primary Amino Acid Derivatives: Compounds with Anticonvulsant and Neuropathic Pain Protection Activities
King, Amber M, Salomé, Christophe, Dinsmore, Jason, Salomé-Grosjean, Elise, De Ryck, Marc, Kaminski, Rafal, Valade, Anne, Kohn, Harold
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Journal Article
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides
Baruah, Pranjal K., Dinsmore, Jason, King, Amber M., Salomé, Christophe, De Ryck, Marc, Kaminski, Rafal, Provins, Laurent, Kohn, Harold
Published in Bioorganic & medicinal chemistry (01.06.2012)
Published in Bioorganic & medicinal chemistry (01.06.2012)
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Journal Article
Defining the Structural Parameters That Confer Anticonvulsant Activity by the Site-by-Site Modification of (R)-N′-Benzyl 2-Amino-3-methylbutanamide
King, Amber M, De Ryck, Marc, Kaminski, Rafal, Valade, Anne, Stables, James P, Kohn, Harold
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Journal Article
Primary Amino Acid Derivatives: Substitution of the 4′-N′-Benzylamide Site in (R)-N′-Benzyl 2-Amino-3-methylbutanamide, (R)-N′-Benzyl 2-Amino-3,3-dimethylbutanamide, and (R)-N′-Benzyl 2-Amino-3-methoxypropionamide Provides Potent Anticonvulsants with Pain-Attenuating Properties
King, Amber M, Salomé, Christophe, Salomé-Grosjean, Elise, De Ryck, Marc, Kaminski, Rafal, Valade, Anne, Stables, James P, Kohn, Harold
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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Journal Article
Identification of the Benzyloxyphenyl Pharmacophore: A Structural Unit That Promotes Sodium Channel Slow Inactivation
King, Amber M, Yang, Xiao-Fang, Wang, Yuying, Dustrude, Erik T, Barbosa, Cindy, Due, Michael R, Piekarz, Andrew D, Wilson, Sarah M, White, Fletcher A, Salomé, Christophe, Cummins, Theodore R, Khanna, Rajesh, Kohn, Harold
Published in ACS chemical neuroscience (19.12.2012)
Published in ACS chemical neuroscience (19.12.2012)
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