Harnessing metabolic dependencies in pancreatic cancers
Encarnación-Rosado, Joel, Kimmelman, Alec C.
Published in Nature reviews. Gastroenterology & hepatology (01.07.2021)
Published in Nature reviews. Gastroenterology & hepatology (01.07.2021)
Get full text
Journal Article
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Mancias, Joseph D., Wang, Xiaoxu, Gygi, Steven P., Harper, J. Wade, Kimmelman, Alec C.
Published in Nature (London) (01.05.2014)
Published in Nature (London) (01.05.2014)
Get full text
Journal Article
KRAS: feeding pancreatic cancer proliferation
Bryant, Kirsten L., Mancias, Joseph D., Kimmelman, Alec C., Der, Channing J.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.02.2014)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.02.2014)
Get full text
Journal Article
Genetics and biology of pancreatic ductal adenocarcinoma
Ying, Haoqiang, Dey, Prasenjit, Yao, Wantong, Kimmelman, Alec C, Draetta, Giulio F, Maitra, Anirban, DePinho, Ronald A
Published in Genes & development (15.02.2016)
Published in Genes & development (15.02.2016)
Get full text
Journal Article
A framework for advancing our understanding of cancer-associated fibroblasts
Sahai, Erik, Astsaturov, Igor, Cukierman, Edna, DeNardo, David G., Egeblad, Mikala, Evans, Ronald M., Fearon, Douglas, Greten, Florian R., Hingorani, Sunil R., Hunter, Tony, Hynes, Richard O., Jain, Rakesh K., Janowitz, Tobias, Jorgensen, Claus, Kimmelman, Alec C., Kolonin, Mikhail G., Maki, Robert G., Powers, R. Scott, Puré, Ellen, Ramirez, Daniel C., Scherz-Shouval, Ruth, Sherman, Mara H., Stewart, Sheila, Tlsty, Thea D., Tuveson, David A., Watt, Fiona M., Weaver, Valerie, Weeraratna, Ashani T., Werb, Zena
Published in Nature reviews. Cancer (01.03.2020)
Published in Nature reviews. Cancer (01.03.2020)
Get full text
Journal Article
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms
Yang, Annan, Herter-Sprie, Grit, Zhang, Haikuo, Lin, Elaine Y, Biancur, Douglas, Wang, Xiaoxu, Deng, Jiehui, Hai, Josephine, Yang, Shenghong, Wong, Kwok-Kin, Kimmelman, Alec C
Published in Cancer discovery (01.03.2018)
Published in Cancer discovery (01.03.2018)
Get full text
Journal Article
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Tintelnot, Joseph, Xu, Yang, Lesker, Till R., Schönlein, Martin, Konczalla, Leonie, Giannou, Anastasios D., Pelczar, Penelope, Kylies, Dominik, Puelles, Victor G., Bielecka, Agata A., Peschka, Manuela, Cortesi, Filippo, Riecken, Kristoffer, Jung, Maximilian, Amend, Lena, Bröring, Tobias S., Trajkovic-Arsic, Marija, Siveke, Jens T., Renné, Thomas, Zhang, Danmei, Boeck, Stefan, Strowig, Till, Uzunoglu, Faik G., Güngör, Cenap, Stein, Alexander, Izbicki, Jakob R., Bokemeyer, Carsten, Sinn, Marianne, Kimmelman, Alec C., Huber, Samuel, Gagliani, Nicola
Published in Nature (London) (02.03.2023)
Published in Nature (London) (02.03.2023)
Get full text
Journal Article
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
Banh, Robert S., Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Walters, Beth, Kuljanin, Miljan, Gikandi, Ajami, Wang, Huamin, Mancias, Joseph D., Schneider, Robert J., Pacold, Michael E., Kimmelman, Alec C.
Published in Cell (25.11.2020)
Published in Cell (25.11.2020)
Get full text
Journal Article
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
Ying, Haoqiang, Kimmelman, Alec C., Lyssiotis, Costas A., Hua, Sujun, Chu, Gerald C., Fletcher-Sananikone, Eliot, Locasale, Jason W., Son, Jaekyoung, Zhang, Hailei, Coloff, Jonathan L., Yan, Haiyan, Wang, Wei, Chen, Shujuan, Viale, Andrea, Zheng, Hongwu, Paik, Ji-hye, Lim, Carol, Guimaraes, Alexander R., Martin, Eric S., Chang, Jeffery, Hezel, Aram F., Perry, Samuel R., Hu, Jian, Gan, Boyi, Xiao, Yonghong, Asara, John M., Weissleder, Ralph, Wang, Y. Alan, Chin, Lynda, Cantley, Lewis C., DePinho, Ronald A.
Published in Cell (27.04.2012)
Published in Cell (27.04.2012)
Get full text
Journal Article
Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis
Santana-Codina, Naiara, Roeth, Anjali A., Zhang, Yi, Yang, Annan, Mashadova, Oksana, Asara, John M., Wang, Xiaoxu, Bronson, Roderick T., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C.
Published in Nature communications (23.11.2018)
Published in Nature communications (23.11.2018)
Get full text
Journal Article
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
Biancur, Douglas E., Paulo, Joao A., Małachowska, Beata, Quiles Del Rey, Maria, Sousa, Cristovão M., Wang, Xiaoxu, Sohn, Albert S. W., Chu, Gerald C., Gygi, Steven P., Harper, J. Wade, Fendler, Wojciech, Mancias, Joseph D., Kimmelman, Alec C.
Published in Nature communications (03.07.2017)
Published in Nature communications (03.07.2017)
Get full text
Journal Article
Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11
Mukhopadhyay, Subhadip, Biancur, Douglas E., Parker, Seth J., Yamamoto, Keisuke, Banh, Robert S., Paulo, Joao A., Mancias, Joseph D., Kimmelman, Alec C.
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2021)
Get full text
Journal Article
Metabolic signature identifies novel targets for drug resistance in multiple myeloma
Maiso, Patricia, Huynh, Daisy, Moschetta, Michele, Sacco, Antonio, Aljawai, Yosra, Mishima, Yuji, Asara, John M, Roccaro, Aldo M, Kimmelman, Alec C, Ghobrial, Irene M
Published in Cancer research (Chicago, Ill.) (15.05.2015)
Published in Cancer research (Chicago, Ill.) (15.05.2015)
Get full text
Journal Article