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Rheault, Tara R., Stellwagen, John C., Adjabeng, George M., Hornberger, Keith R., Petrov, Kimberly G., Waterson, Alex G., Dickerson, Scott H., Mook, Robert A., Laquerre, Sylvie G., King, Alastair J., Rossanese, Olivia W., Arnone, Marc R., Smitheman, Kimberly N., Kane-Carson, Laurie S., Han, Chao, Moorthy, Ganesh S., Moss, Katherine G., Uehling, David E.
Published in ACS medicinal chemistry letters (14.03.2013)
Published in ACS medicinal chemistry letters (14.03.2013)
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Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series
Petrov, Kimberly G., Zhang, Yue-Mei, Carter, Malcolm, Cockerill, G. Stuart, Dickerson, Scott, Gauthier, Cassandra A., Guo, Yu, Mook, Robert A., Rusnak, David W., Walker, Ann L., Wood, Edgar R., Lackey, Karen E.
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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Wood, Edgar R, Shewchuk, Lisa M, Ellis, Byron, Brignola, Perry, Brashear, Ronald L, Caferro, Thomas R, Dickerson, Scott H, Dickson, Hamilton D, Donaldson, Kelly H, Gaul, Michael, Griffin, Robert J, Hassell, Anne M, Keith, Barry, Mullin, Robert, Petrov, Kimberly G, Reno, Michael J, Rusnak, David W, Tadepalli, Sarva M, Ulrich, John C, Wagner, Craig D, Vanderwall, Dana E, Waterson, Alex G, Williams, Jon D, White, Wendy L, Uehling, David E
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors
Rheault, Tara R., Caferro, Thomas R., Dickerson, Scott H., Donaldson, Kelly H., Gaul, Michael D., Goetz, Aaron S., Mullin, Robert J., McDonald, Octerloney B., Petrov, Kimberly G., Rusnak, David W., Shewchuk, Lisa M., Spehar, Glenn M., Truesdale, Anne T., Vanderwall, Dana E., Wood, Edgar R., Uehling, David E.
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors
Waterson, Alex G., Petrov, Kimberly G., Hornberger, Keith R., Hubbard, Robert D., Sammond, Douglas M., Smith, Stephon C., Dickson, Hamilton D., Caferro, Thomas R., Hinkle, Kevin W., Stevens, Kirk L., Dickerson, Scott H., Rusnak, David W., Spehar, Glenn M., Wood, Edgar R., Griffin, Robert J., Uehling, David E.
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors
Stevens, Kirk L., Alligood, Krystal J., Alberti, Jennifer G. Badiang, Caferro, Thomas R., Chamberlain, Stanley D., Dickerson, Scott H., Dickson, Hamilton D., Emerson, Holly K., Griffin, Robert J., Hubbard, Robert D., Keith, Barry R., Mullin, Robert J., Petrov, Kimberly G., Gerding, Roseanne M., Reno, Michael J., Rheault, Tara R., Rusnak, David W., Sammond, Douglas M., Smith, Stephon C., Uehling, David E., Waterson, Alex G., Wood, Edgar R.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article
Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup
STELLWAGEN, John C, ADJABENG, George M, ROMINGER, Cynthia M, ROSSANESE, Olivia W, SMITHEMAN, Kimberly N, WATERSON, Alex G, UEHLING, David E, ARNONE, Marc R, DICKERSON, Scott H, CHAO HAN, HORNBERGER, Keith R, KING, Alastair J, MOOK, Robert A, PETROV, Kimberly G, RHEAULT, Tara R
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
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Journal Article
Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping
Lambert, Millard H, Blackburn, R Kevin, Seaton, Theresa D, Kassel, Daniel B, Kinder, Daniel S, Leesnitzer, M Anthony, Bickett, D Mark, Warner, Janet R, Andersen, Marc W, Badiang, Jennifer G, Cowan, David J, Gaul, Michael D, Petrov, Kimberly G, Rabinowitz, Michael H, Wiethe, Robert W, Becherer, J David, McDougald, Darryl L, Musso, David L, Andrews, Robert C, Moss, Marcia L
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Published in Combinatorial chemistry & high throughput screening (01.06.2005)
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Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2
Haffner, Curt D., Thomson, Stephen A., Guo, Yu, Petrov, Kimberly, Larkin, Andrew, Banker, Pierette, Schaaf, Gregory, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, J. Patrick, Poole, Chuck, Carpenter, Tiffany, Ulrich, John
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
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Journal Article
Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}b enzamide analogs as potent Kv1.3 ion channel blockers. Part 2
Haffner, Curt D, Thomson, Stephen A, Guo, Yu, Petrov, Kimberly, Larkin, Andrew, Banker, Pierette, Schaaf, Gregory, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, JPatrick, Poole, Chuck, Carpenter, Tiffany, Ulrich, John
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
Published in Bioorganic & medicinal chemistry letters (01.12.2010)
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Development of potent B-Raf super(V600E inhibitors containing an arylsulfonamide headgroup)
Stellwagen, John C, Adjabeng, George M, Arnone, Marc R, Dickerson, Scott H, Han, Chao, Hornberger, Keith R, King, Alastair J, Mook, Robert A, Petrov, Kimberly G, Rheault, Tara R, Rominger, Cynthia M, Rossanese, Olivia W, Smitheman, Kimberly N, Waterson, Alex G, Uehling, David E
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
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Development of potent B-Raf V600E inhibitors containing an arylsulfonamide headgroup
Stellwagen, John C., Adjabeng, George M., Arnone, Marc R., Dickerson, Scott H., Han, Chao, Hornberger, Keith R., King, Alastair J., Mook, Robert A., Petrov, Kimberly G., Rheault, Tara R., Rominger, Cynthia M., Rossanese, Olivia W., Smitheman, Kimberly N., Waterson, Alex G., Uehling, David E.
Published in Bioorganic & medicinal chemistry letters (2011)
Published in Bioorganic & medicinal chemistry letters (2011)
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6-Ethynylthieno[3,2-d]- and 6-ethynyithieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases
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Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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