DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer
Agarwal, Sumit, Afaq, Farrukh, Bajpai, Prachi, Kim, Hyung‐Gyoon, Elkholy, Amr, Behring, Michael, Chandrashekar, Darshan Shimoga, Diffalha, Sameer Al, Khushman, Moh’d, Sugandha, Shajan P., Varambally, Sooryanarayana, Manne, Upender
Published in Molecular oncology (01.04.2022)
Published in Molecular oncology (01.04.2022)
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TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status
Agarwal, Sumit, Behring, Michael, Kim, Hyung‐Gyoon, Chandrashekar, Darshan S., Chakravarthi, Balabhadrapatruni V. S. K., Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Al Diffalha, Sameer, Datta, Pran K., Heslin, Martin J., Varambally, Sooryanarayana, Manne, Upender
Published in Molecular oncology (01.12.2020)
Published in Molecular oncology (01.12.2020)
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Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
Afaq, Farrukh, Agarwal, Sumit, Bajpai, Prachi, Diffalha, Sameer Al, Kim, Hyung-Gyoon, Peter, Shajan, Khushman, Moh'd, Chauhan, Subhash C, Mukherjee, Priyabrata, Varambally, Sooryanarayana, Manne, Upender
Published in Neoplasia (New York, N.Y.) (01.01.2024)
Published in Neoplasia (New York, N.Y.) (01.01.2024)
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Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model
Agarwal, Sumit, Behring, Michael, Kim, Hyung-Gyoon, Bajpai, Prachi, Chakravarthi, Balabhadrapatruni V.S.K., Gupta, Nirzari, Elkholy, Amr, Al Diffalha, Sameer, Varambally, Sooryanarayana, Manne, Upender
Published in Translational oncology (01.04.2020)
Published in Translational oncology (01.04.2020)
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Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics
Bajpai, Prachi, Banerjee, Nilam Sanjib, Moore, Dianne W, Kim, Hyung-Gyoon, Afaq, Farrukh, Contreras, Carlo M, Heslin, Martin J, Reddy, Vishnu B, Peter, Shajan, Varambally, Sooryanarayana, Al Diffalha, Sameer, Manne, Upender
Published in International journal of molecular sciences (19.11.2022)
Published in International journal of molecular sciences (19.11.2022)
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PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer
Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V S K, Behring, Michael, Kim, Hyung-Gyoon, Chandrashekar, Darshan S, Gupta, Nirzari, Bajpai, Prachi, Elkholy, Amr, Balasubramanya, Sai A H, Hardy, Cherlene, Diffalha, Sameer Al, Varambally, Sooryanarayana, Manne, Upender
Published in Cancers (25.03.2020)
Published in Cancers (25.03.2020)
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Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women
Saleh, Mansoor, Chandrashekar, Darshan Shimoga, Shahin, Sayed, Agarwal, Sumit, Kim, Hyung-Gyoon, Behring, Michael, Shaikh, Asim Jamal, Moloo, Zahir, Eltoum, Isam-Eldin A, Yates, Clayton, Varambally, Sooryanarayana, Manne, Upender
Published in Translational oncology (01.07.2021)
Published in Translational oncology (01.07.2021)
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Immunophenotype‐associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent
Behring, Michael, Ye, Yuanfan, Elkholy, Amr, Bajpai, Prachi, Agarwal, Sumit, Kim, Hyung‐Gyoon, Ojesina, Akinyemi I., Wiener, Howard W, Manne, Upender, Shrestha, Sadeep, Vazquez, Ana I.
Published in Cancer medicine (Malden, MA) (01.08.2021)
Published in Cancer medicine (Malden, MA) (01.08.2021)
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PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression
Agarwal, Sumit, Chakravarthi, Balabhadrapatruni V.S.K., Kim, Hyung-Gyoon, Gupta, Nirzari, Hale, Kevin, Balasubramanya, Sai Akshaya Hodigere, Oliver, Patsy G., Thomas, Dafydd G., Eltoum, Isam-Eldin A., Buchsbaum, Donald J., Manne, Upender, Varambally, Sooryanarayana
Published in Translational oncology (01.07.2020)
Published in Translational oncology (01.07.2020)
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Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage
Thal, Melissa A, Carvalho, Thiago L, He, Ti, Kim, Hyung-Gyoon, Gao, Hua, Hagman, James, Klug, Christopher A
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (13.01.2009)
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Molecular disparities in colorectal cancers of White Americans, Alabama African Americans, and Oklahoma American Indians
Yamada, Hiroshi Y., Xu, Chao, Jones, Kenneth L., O’Neill, Philip H., Venkateshwar, Madka, Chiliveru, Srikanth, Kim, Hyung-Gyoon, Doescher, Mark, Morris, Katherine T., Manne, Upender, Rao, Chinthalapally V.
Published in NPJ precision oncology (19.08.2023)
Published in NPJ precision oncology (19.08.2023)
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Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients
Elkholy, Amr, Avuthu, Nagavardhini, Abdalla, Mohammed, Behring, Michael, Bajpai, Prachi, Kim, Hyung-Gyoon, Header, Doaa, Abo Elwafa, Reham AH, Saed, Hesham, Embaby, Amira, El-Nikhely, Nefertiti, Obuya, Sarah, Mohamed, Mostafa, Badawy, Ahmed Ashour, Nawar, Ahmed, Afaq, Farrukh, Rogers, Laura Q., Bae, Sejong, Shikany, James M., Bateman, Lori Brand, Fouad, Mona, Saleh, Mansoor, Samuel, Temesgen, Varambally, Sooryanarayana, Guda, Chittibabu, Arafat, Waleed, Manne, Upender
Published in Heliyon (01.07.2023)
Published in Heliyon (01.07.2023)
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Journal Article
BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis
Agarwal, Sumit, Afaq, Farrukh, Bajpai, Prachi, Behring, Michael, Kim, Hyung-Gyoon, Varambally, Amith, Chandrashekar, Darshan S, Peter, Shajan, Diffalha, Sameer Al, Khushman, Moh'd, Seeber, Andreas, Varambally, Sooryanarayana, Manne, Upender
Published in Molecular cancer research (05.07.2023)
Published in Molecular cancer research (05.07.2023)
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The ETS family transcription factor PU.1 is necessary for the maintenance of fetal liver hematopoietic stem cells
Kim, Hyung-Gyoon, de Guzman, Cristina G., Swindle, C. Scott, Cotta, Claudiu V., Gartland, Larry, Scott, Edward W., Klug, Christopher A.
Published in Blood (15.12.2004)
Published in Blood (15.12.2004)
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Absence of inhibition of cutaneous wound healing in mice by oral doxycycline
Hebda, Patricia A., Whaley, Diana, Kim, Hyung-Gyoon, Wells, Alan
Published in Wound repair and regeneration (01.09.2003)
Published in Wound repair and regeneration (01.09.2003)
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Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer
Bajpai, Prachi, Agarwal, Sumit, Afaq, Farrukh, Al Diffalha, Sameer, Chandrashekar, Darshan S, Kim, Hyung-Gyoon, Shelton, Abigail, Miller, C Ryan, Singh, Santosh K, Singh, Rajesh, Varambally, Sooryanarayana, Nagaraju, Ganji Purnachandra, Manne, Ashish, Paluri, Ravi, Khushman, Moh'd, Manne, Upender
Published in Journal of experimental & clinical cancer research (11.07.2024)
Published in Journal of experimental & clinical cancer research (11.07.2024)
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Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations
Davis, Melissa, Martini, Rachel, Newman, Lisa, Elemento, Olivier, White, Jason, Verma, Akanksha, Datta, Indrani, Adrianto, Indra, Chen, Yalei, Gardner, Kevin, Kim, Hyung-Gyoon, Colomb, Windy D, Eltoum, Isam-Eldin, Frost, Andra R, Grizzle, William E, Sboner, Andrea, Manne, Upender, Yates, Clayton
Published in Cancers (13.05.2020)
Published in Cancers (13.05.2020)
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Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia
Kojima, Kyoko, Vickers, Selwyn M, Adsay, N Volkan, Jhala, Nirag C, Kim, Hyung-Gyoon, Schoeb, Trenton R, Grizzle, William E, Klug, Christopher A
Published in Cancer research (Chicago, Ill.) (01.09.2007)
Published in Cancer research (Chicago, Ill.) (01.09.2007)
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The inv(16) Cooperates with ARF Haploinsufficiency to Induce Acute Myeloid Leukemia
Moreno-Miralles, Isabel, Pan, Ling, Keates-Baleeiro, Jennifer, Durst-Goodwin, Kristie, Yang, Chunying, Kim, Hyung-Gyoon, Thompson, Mary Ann, Klug, Christopher A., Cleveland, John L., Hiebert, Scott W.
Published in The Journal of biological chemistry (02.12.2005)
Published in The Journal of biological chemistry (02.12.2005)
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