Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies
Bantia, Shanta, Parker, Cynthia, Upshaw, Ramanda, Cunningham, Amanda, Kotian, Pravin, Kilpatrick, J. Michael, Morris, Philip, Chand, Pooran, Babu, Yarlagadda S.
Published in International immunopharmacology (01.07.2010)
Published in International immunopharmacology (01.07.2010)
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Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2′-deoxyguanosine in primates
Kilpatrick, J.Michael, Morris, Philip E., Serota, David G., Phillips, Deborah, Moore, D.Ray, Bennett, J.Claude, Babu, Y.S.
Published in International immunopharmacology (01.04.2003)
Published in International immunopharmacology (01.04.2003)
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Synthesis and Pharmacokinetic and Pharmacodynamic Evaluation of the Forodesine HCl Analog BCX-3040
Kezar, Hollis S., Kilpatrick, J. Michael, Phillips, Deborah, Kellogg, Debbie, Zhang, Jianwen, Morris, Philip E.
Published in Nucleosides, nucleotides & nucleic acids (01.09.2005)
Published in Nucleosides, nucleotides & nucleic acids (01.09.2005)
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Forodesine (FodosineTM), a PNP Inhibitor Active in Relapsed or Refractory T-Cell Leukemia Patients (Phase II Study)
Furman, Richard R., Iosava, Genadi, Isola, Luis, Ravandi, Farhad, Zodelava, Mamia, Bennett, J. Claude, Kilpatrick, J. Michael, Bantia, Shanta
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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Intravenous Forodesine (BCX-1777), a Novel Purine Nucleoside Phosphorylase (PNP) Inhibitor, Demonstrates Clinical Activity in Phase I/II Studies in Patients with B-Cell Acute Lymphoblastic Leukemia
Furman, Richard R., Gandhi, Varsha V., Bennett, J. Claude, Bantia, Shanta, Kilpatrick, J. Michael
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Intravenous Forodesine (BCX-1777), a Novel Purine Nucleoside Phosphorylase (PNP) Inhibitor, Demonstrates Clinical Activity in Patients with Refractory Cutaneous T-Cell Lymphoma
Duvic, Madeleine, Foss, Francine M., Olsen, Elise A., Forero-Torres, Andres, Bennett, J. Claude, Bantia, Shanta, Kilpatrick, J. Michael
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Antileukemic Activity and Pharmacodynamics of Intravenous Forodesine (BCX-1777), a Novel Purine Nucleoside Phosphorylase (PNP) Inhibitor, in Phase I/II Trials in Patients with Advanced T-Cell Malignancies
Isola, Luis, Furman, Richard R., Gandhi, Varsha, Thomas, Deborah A., Bennett, J. Claude, Bantia, Shanta, Kilpatrick, J. Michael
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Structures of native and complexed complement factor D: implications of the atypical his57 conformation and self-inhibitory loop in the regulation of specific serine protease activity
Jing, Hua, Babu, Y.Sudhakara, Moore, Dwight, Kilpatrick, J.Michael, Liu, Xiao-Ying, Volanakis, John E., Narayana, Sthanam V.L.
Published in Journal of molecular biology (09.10.1998)
Published in Journal of molecular biology (09.10.1998)
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AN EVALUATION OF THE DIAGNOSTIC VALUE OF SYNTHETIC LUTEINIZING HORMONE RELEASING HORMONE
Newton, J R, Kilpatrick, M J, Pike, J M, Collins, W P
Published in Acta endocrinologica (Copenhagen) (01.11.1975)
Published in Acta endocrinologica (Copenhagen) (01.11.1975)
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Structure of human factor D : a complement system protein at 2.0 Å resolution
NARAYANA, S. V. L, CARSON, M, EL-KABBANI, O, KILPATRICK, J. M, MOORE, D, XI CHEN, BUGG, C. E, VOLANAKIS, J. E, DELUCAS, L. J
Published in Journal of molecular biology (14.01.1994)
Published in Journal of molecular biology (14.01.1994)
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Structure of 3,4-Dichloroisocoumarin-Inhibited Factor D
Cole, L. Brent, Kilpatrick, J. Michael, Chu, Naiming, Babu, Y. Sudhakar
Published in Acta crystallographica. Section D, Biological crystallography. (01.09.1998)
Published in Acta crystallographica. Section D, Biological crystallography. (01.09.1998)
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Structure of Diisopropyl Fluorophosphate-Inhibited Factor D
Cole, L. B., Chu, N., Kilpatrick, J. M., Volanakis, J. E., Narayana, S. V., Babu, Y. S.
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.1997)
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.1997)
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