Mutant KRAS is a druggable target for pancreatic cancer
Khvalevsky, Elina Zorde, Gabai, Racheli, Rachmut, Itzhak Haim, Horwitz, Elad, Brunschwig, Zivia, Orbach, Ariel, Shemi, Adva, Golan, Talia, Domb, Abraham J., Yavin, Eylon, Giladi, Hilla, Rivkin, Ludmila, Simerzin, Alina, Eliakim, Rami, Khalaileh, Abed, Hubert, Ayala, Lahav, Maor, Kopelman, Yael, Goldin, Eran, Dancour, Alan, Hants, Yael, Arbel-Alon, Sagit, Abramovitch, Rinat, Shemi, Amotz, Galun, Eithan
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Journal Article
The liver‐specific microRNA‐122, the complementary strand of microRNA‐122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry
Simerzin, Alina, Zorde‐Khvalevsky, Elina, Rivkin, Mila, Adar, Revital, Zucman‐Rossi, Jessica, Couchy, Gabrielle, Roskams, Tania, Govaere, Olivier, Oren, Moshe, Giladi, Hilla, Galun, Eithan
Published in Hepatology (Baltimore, Md.) (01.11.2016)
Published in Hepatology (Baltimore, Md.) (01.11.2016)
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Journal Article
Preclinical Safety Evaluation in Rats of a Polymeric Matrix Containing an siRNA Drug Used as a Local and Prolonged Delivery System for Pancreatic Cancer Therapy
Ramot, Yuval, Rotkopf, Shay, Gabai, Rachel Malka, Zorde Khvalevsky, Elina, Muravnik, Sofia, Marzoli, Gabriela Alejandra, Domb, Abraham J, Shemi, Amotz, Nyska, Abraham
Published in Toxicologic pathology (01.08.2016)
Published in Toxicologic pathology (01.08.2016)
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Journal Article
Comprehensive gene and microRNA expression profiling reveals a role for microRNAs in human liver development
Tzur, Galit, Israel, Ariel, Levy, Asaf, Benjamin, Hila, Meiri, Eti, Shufaro, Yoel, Meir, Karen, Khvalevsky, Elina, Spector, Yael, Rojansky, Nathan, Bentwich, Zvi, Reubinoff, Benjamin E, Galun, Eithan
Published in PloS one (20.10.2009)
Published in PloS one (20.10.2009)
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Journal Article
TLR3 signaling in a hepatoma cell line is skewed towards apoptosis
Khvalevsky, Elina, Rivkin, Ludmila, Rachmilewitz, Jacob, Galun, Eithan, Giladi, Hilla
Published in Journal of cellular biochemistry (01.04.2007)
Published in Journal of cellular biochemistry (01.04.2007)
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Journal Article
Toll‐like receptor 3 signaling attenuates liver regeneration
Zorde‐Khvalevsky, Elina, Abramovitch, Rinat, Barash, Hila, Spivak‐Pohis, Irit, Rivkin, Ludmila, Rachmilewitz, Jacob, Galun, Eithan, Giladi, Hilla
Published in Hepatology (Baltimore, Md.) (01.07.2009)
Published in Hepatology (Baltimore, Md.) (01.07.2009)
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Journal Article
Incomplete thermal ablation of tumors promotes increased tumorigenesis
Markezana, Aurelia, Goldberg, S. Nahum, Kumar, Gaurav, Zorde-Khvalevsky, Elina, Gourevtich, Svetlana, Rozenblum, Nir, Galun, Eithan, Ahmed, Muneeb
Published in International journal of hyperthermia (01.01.2021)
Published in International journal of hyperthermia (01.01.2021)
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Journal Article
Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation
Markezana, Aurelia, Paldor, Mor, Liao, Haixing, Ahmed, Muneeb, Zorde-Khvalevsky, Elina, Rozenblum, Nir, Stechele, Matthias, Salvermoser, Lukas, Laville, Flinn, Goldmann, Salome, Rosenberg, Nofar, Andrasina, Tomas, Ricke, Jens, Galun, Eithan, Goldberg, Shraga Nahum
Published in Scientific reports (28.09.2023)
Published in Scientific reports (28.09.2023)
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Journal Article
Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity
Markezana, Aurelia, Ahmed, Muneeb, Kumar, Gaurav, Zorde-Khvalevsky, Elina, Rozenblum, Nir, Galun, Eithan, Goldberg, S. Nahum
Published in International journal of hyperthermia (01.01.2020)
Published in International journal of hyperthermia (01.01.2020)
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Journal Article
DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity
Cendrowicz, Ewa, Jacob, Lisa, Greenwald, Shirley, Tamir, Ami, Pecker, Iris, Tabakman, Rinat, Ghantous, Lucy, Tamir, Liat, Kahn, Roy, Avichzer, Jasmine, Aronin, Alexandra, Amsili, Shira, Zorde-Khvalevsky, Elina, Gozlan, Yosi, Vlaming, Martijn, Huls, Gerwin, van Meerten, Tom, Dranitzki, Michal Elhalel, Foley-Comer, Adam, Pereg, Yaron, Peled, Amnon, Chajut, Ayelet, Bremer, Edwin
Published in Journal of experimental & clinical cancer research (14.03.2022)
Published in Journal of experimental & clinical cancer research (14.03.2022)
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Journal Article
Multistep, effective drug distribution within solid tumors
Shemi, Amotz, Khvalevsky, Elina Zorde, Gabai, Rachel Malka, Domb, Abraham, Barenholz, Yechezkel
Published in Oncotarget (24.11.2015)
Published in Oncotarget (24.11.2015)
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Journal Article
790 DSP502 — A novel approach for targeting TIGIT and PD1 pathways for cancer immunotherapy
Chajut, Ayelet, Greenwald, Shirley, Weber, Matthew, Tamir, Ami, Pecker, Iris, Tabakman, Rinat, Ganthous, Lucy, Tamir, Liat, Kahn, Roy, Avichzer, Jasmine, Aronin, Alexandra, Zorde-Khvalevsky, Elina, Peled, Amnon, Elhalel Dranitzki, Michal Michal, Foley-Comer, Adam, Tykocinski, Mark
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
Chai, Chofit, Rivkin, Mila, Berkovits, Liav, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rosenberg, Nofar, Klein, Shiri, Yaish, Dayana, Durst, Ronen, Shpitzen, Shoshana, Udi, Shiran, Tam, Joseph, Heeren, Joerg, Worthmann, Anna, Schramm, Christoph, Kluwe, Johannes, Ravid, Revital, Hornstein, Eran, Giladi, Hilla, Galun, Eithan
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2017)
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Journal Article
RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients
Golan, Talia, Khvalevsky, Elina Zorde, Hubert, Ayala, Gabai, Rachel Malka, Hen, Naama, Segal, Amiel, Domb, Abraham, Harari, Gil, David, Eliel Ben, Raskin, Stephen, Goldes, Yuri, Goldin, Eran, Eliakim, Rami, Lahav, Maor, Kopleman, Yael, Dancour, Alain, Shemi, Amotz, Galun, Eithan
Published in Oncotarget (15.09.2015)
Published in Oncotarget (15.09.2015)
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Journal Article
Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo
Rodionov, Galina, Rosenzwaig, Michal, Tzadok, Michal Schrift, Kvint, Moran, Gevir, Elazar, Zorde-Khvalevsky, Elina, Peled, Amnon, Yarkoni, Shai, Ofer, Amos
Published in Bone marrow transplantation (Basingstoke) (01.08.2022)
Published in Bone marrow transplantation (Basingstoke) (01.08.2022)
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Journal Article
Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-Derived Erythropoietin and Anemia
Rivkin, Mila, Simerzin, Alina, Zorde-Khvalevsky, Elina, Chai, Chofit, Yuval, Jonathan B, Rosenberg, Nofar, Harari-Steinfeld, Rona, Schneider, Ronen, Amir, Gail, Condiotti, Reba, Heikenwalder, Mathias, Weber, Achim, Schramm, Christoph, Wege, Henning, Kluwe, Johannes, Galun, Eithan, Giladi, Hilla
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2016)
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Journal Article
The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADD
Harari-Steinfeld, Rona, Gefen, Maytal, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rivkin, Mila, Ella, Ezra, Friehmann, Tomer, Gerlic, Mordechay, Zucman-Rossi, Jessica, Caruso, Stefano, Leveille, Mélissa, Estall, Jennifer L, Goldenberg, Daniel S, Giladi, Hilla, Galun, Eithan, Bromberg, Zohar
Published in Cancers (22.01.2021)
Published in Cancers (22.01.2021)
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Journal Article
THU-374-The INCRNA H19-dervied MIR-675 promotes liver necroptosis by targeting fadd
Galun, Eithan, Harai-Steinfeld, Rona, Gefen, Meytal, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rivkin, Mila, Ella, Ezra, Friehmann, Tomer, Gerlic, Mordeachy, Zucman-Rossi, Jessica, Caruso, Stefano, Leveille, Melissa, Estall, Jennifer, Goldenberg, Daniel S, Giladi, Hilla, Bromberg, Zohar
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
DSP107 combines inhibition of CD47/SIRP[alpha] axis with activation of 4-1BB to trigger anticancer immunity
Zorde-Khvalevsky, Elina, Kahn, Roy, Amsili, Shira, Tamir, Liat, Vlaming, Martijn, Chajut, Ayelet, Avichzer, Jasmine, Aronin, Alexandra, Tamir, Ami, Tabakman, Rinat, Huls, Gerwin, Gozlan, Yosi, Pereg, Yaron, Ghantous, Lucy, Cendrowicz, Ewa, Pecker, Iris, Bremer, Edwin, Jacob, Lisa, van Meerten, Tom, Foley-Comer, Adam, Greenwald, Shirley, Dranitzki, Michal Elhalel, Peled, Amnon
Published in Journal of experimental & clinical cancer research (14.03.2022)
Published in Journal of experimental & clinical cancer research (14.03.2022)
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Journal Article
Novel Kras-directed therapy in combination with chemotherapy for locally advanced pancreatic adenocarcinoma
Golan, Talia, Hubert, Ayala, Shemi, Amotz, Segal, Amiel, Khvalevsky, Elina Zorde, Domb, Avi, Ben-David, Eliel, Raskin, Stephen, Goldes, Yuri, Lahav, Maor, Dancour, Alan, Galun, Eithan
Published in Journal of clinical oncology (20.01.2014)
Published in Journal of clinical oncology (20.01.2014)
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