Amplification of neurotoxic HTTex1 assemblies in human neurons
Chongtham, Anjalika, Isas, J. Mario, Pandey, Nitin K., Rawat, Anoop, Yoo, Jung Hyun, Mastro, Tara, Kennedy, Mary B., Langen, Ralf, Khoshnan, Ali
Published in Neurobiology of disease (01.11.2021)
Published in Neurobiology of disease (01.11.2021)
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Corrigendum: Gut bacteria regulate the pathogenesis of Huntington's disease in Drosophila model
Chongtham, Anjalika, Yoo, Jung Hyun, Chin, Theodore M., Akingbesote, Ngozi D., Huda, Ainul, Marsh, J. Lawrence, Khoshnan, Ali
Published in Frontiers in neuroscience (13.10.2022)
Published in Frontiers in neuroscience (13.10.2022)
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Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice
Schindler, Franziska, Praedel, Nicole, Neuendorf, Nancy, Kunz, Severine, Schnoegl, Sigrid, Mason, Michael A., Taxy, Bridget A., Bates, Gillian P., Khoshnan, Ali, Priller, Josef, Grimm, Jan, Maier, Marcel, Boeddrich, Annett, Wanker, Erich E.
Published in Frontiers in neuroscience (22.06.2021)
Published in Frontiers in neuroscience (22.06.2021)
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IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin
Khoshnan, Ali, Ko, Jan, Tescu, Simona, Brundin, Patrick, Patterson, Paul H
Published in PloS one (02.06.2009)
Published in PloS one (02.06.2009)
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
Thompson, Leslie Michels, Aiken, Charity T, Kaltenbach, Linda S, Agrawal, Namita, Illes, Katalin, Khoshnan, Ali, Martinez-Vincente, Marta, Arrasate, Montserrat, O'Rourke, Jacqueline Gire, Khashwji, Hasan, Lukacsovich, Tamas, Zhu, Ya-Zhen, Lau, Alice L, Massey, Ashish, Hayden, Michael R, Zeitlin, Scott O, Finkbeiner, Steven, Green, Kim N, LaFerla, Frank M, Bates, Gillian, Huang, Lan, Patterson, Paul H, Lo, Donald C, Cuervo, Ana Maria, Marsh, J. Lawrence, Steffan, Joan S
Published in The Journal of cell biology (28.12.2009)
Published in The Journal of cell biology (28.12.2009)
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IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD
Khoshnan, Ali, Sabbaugh, Adam, Calamini, Barbara, Marinero, Steven A, Dunn, Denise E, Yoo, Jung Hyun, Ko, Jan, Lo, Donald C, Patterson, Paul H
Published in Human molecular genetics (01.11.2017)
Published in Human molecular genetics (01.11.2017)
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Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin
Ko, Jan, Isas, J Mario, Sabbaugh, Adam, Yoo, Jung Hyun, Pandey, Nitin K, Chongtham, Anjalika, Ladinsky, Mark, Wu, Wei-Li, Rohweder, Heike, Weiss, Andreas, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Langen, Ralf, Patterson, Paul H, Khoshnan, Ali
Published in Human molecular genetics (01.07.2018)
Published in Human molecular genetics (01.07.2018)
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DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease
Sajjad, Muhammad U, Green, Edward W, Miller-Fleming, Leonor, Hands, Sarah, Herrera, Federico, Campesan, Susanna, Khoshnan, Ali, Outeiro, Tiago F, Giorgini, Flaviano, Wyttenbach, Andreas
Published in Human molecular genetics (01.02.2014)
Published in Human molecular genetics (01.02.2014)
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IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin
Khoshnan, Ali, Ko, Jan, Tescu, Simona, Brundin, Patrick, Patterson, Paul H.
Published in PloS one (02.06.2009)
Published in PloS one (02.06.2009)
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