The inflammasome pathway is amplified and perpetuated in an autocrine manner through connexin43 hemichannel mediated ATP release
Mugisho, Odunayo O., Green, Colin R., Kho, Dan T., Zhang, Jie, Graham, E. Scott, Acosta, Monica L., Rupenthal, Ilva D.
Published in Biochimica et biophysica acta. General subjects (01.03.2018)
Published in Biochimica et biophysica acta. General subjects (01.03.2018)
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Journal Article
Cannabinoid Receptor 2 (CB2) Signals via G‑alpha‑s and Induces IL‑6 and IL-10 Cytokine Secretion in Human Primary Leukocytes
Saroz, Yurii, Kho, Dan T, Glass, Michelle, Graham, Euan Scott, Grimsey, Natasha Lillia
Published in ACS pharmacology & translational science (13.12.2019)
Published in ACS pharmacology & translational science (13.12.2019)
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Journal Article
Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation
van Kralingen, Christa, Kho, Dan Ting, Costa, Jessica, Angel, Catherine Elizabeth, Graham, E Scott
Published in PloS one (19.12.2013)
Published in PloS one (19.12.2013)
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Journal Article
The Importance of Multifrequency Impedance Sensing of Endothelial Barrier Formation Using ECIS Technology for the Generation of a Strong and Durable Paracellular Barrier
Robilliard, Laverne D, Kho, Dan T, Johnson, Rebecca H, Anchan, Akshata, O'Carroll, Simon J, Graham, Euan Scott
Published in Biosensors (Basel) (04.07.2018)
Published in Biosensors (Basel) (04.07.2018)
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Journal Article
Application of xCELLigence RTCA Biosensor Technology for Revealing the Profile and Window of Drug Responsiveness in Real Time
Kho, Dan, MacDonald, Christa, Johnson, Rebecca, Unsworth, Charles P, O'Carroll, Simon J, du Mez, Elyce, Angel, Catherine E, Graham, E Scott
Published in Biosensors (Basel) (16.04.2015)
Published in Biosensors (Basel) (16.04.2015)
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Journal Article
Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier
Griffin, Jarred M, Kho, Dan, Graham, E Scott, Nicholson, Louise F B, O'Carroll, Simon J
Published in PloS one (16.06.2016)
Published in PloS one (16.06.2016)
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Journal Article
An anti-inflammatory role for C/EBPδ in human brain pericytes
Rustenhoven, Justin, Scotter, Emma L., Jansson, Deidre, Kho, Dan T., Oldfield, Robyn L., Bergin, Peter S., Mee, Edward W., Faull, Richard L. M., Curtis, Maurice A., Graham, Scott E., Park, Thomas I-H., Dragunow, Mike
Published in Scientific reports (13.07.2015)
Published in Scientific reports (13.07.2015)
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Journal Article
In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology
Gu, Andrea Y, Kho, Dan T, Johnson, Rebecca H, Graham, E Scott, O'Carroll, Simon J
Published in Biosensors (Basel) (11.10.2018)
Published in Biosensors (Basel) (11.10.2018)
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Journal Article
ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα
Kho, Dan Ting, Johnson, Rebecca, Robilliard, Laverne, du Mez, Elyce, McIntosh, Julie, O'Carroll, Simon J, Angel, Catherine E, Graham, E Scott
Published in PloS one (21.07.2017)
Published in PloS one (21.07.2017)
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Journal Article
Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology
Anchan, Akshata, Kalogirou-Baldwin, Panagiota, Johnson, Rebecca, Kho, Dan T, Joseph, Wayne, Hucklesby, James, Finlay, Graeme J, O'Carroll, Simon J, Angel, Catherine E, Graham, E Scott
Published in Biosensors (Basel) (15.04.2019)
Published in Biosensors (Basel) (15.04.2019)
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Journal Article
Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products
Kho, Dan T, Johnson, Rebecca H, O'Carroll, Simon J, Angel, Catherine E, Graham, E Scott
Published in Biosensors (Basel) (21.09.2017)
Published in Biosensors (Basel) (21.09.2017)
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Journal Article
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors
Wiltshire, Rachael, Nelson, Vicky, Kho, Dan Ting, Angel, Catherine E., O’Carroll, Simon J., Graham, E. Scott
Published in Scientific reports (27.01.2016)
Published in Scientific reports (27.01.2016)
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Journal Article
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
O'Carroll, Simon J, Kho, Dan Ting, Wiltshire, Rachael, Nelson, Vicky, Rotimi, Odunayo, Johnson, Rebecca, Angel, Catherine E, Graham, E Scott
Published in Journal of neuroinflammation (08.07.2015)
Published in Journal of neuroinflammation (08.07.2015)
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Journal Article
ECIS technology reveals that monocytes isolated by CD14.sup.+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1[beta] activated endothelium in comparison to TNF[alpha]
Kho, Dan Ting, Johnson, Rebecca, Robilliard, Laverne, du Mez, Elyce, McIntosh, Julie, O'Carroll, Simon J, Angel, Catherine E, Graham, E. Scott
Published in PloS one (21.07.2017)
Published in PloS one (21.07.2017)
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Journal Article
Pro-inflammatory TNF[alpha] and IL-1[beta] differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
O'Carroll, Simon J, Kho, Dan Ting, Wiltshire, Rachael, Nelson, Vicky, Rotimi, Odunayo, Johnson, Rebecca, Angel, Catherine E, Graham, E. Scott
Published in Journal of neuroinflammation (08.07.2015)
Published in Journal of neuroinflammation (08.07.2015)
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Journal Article
Statins Inhibit Fibrillary [Beta]-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier
Griffin, Jarred M, Kho, Dan, Graham, E Scott, Nicholson, Louise FB, O'Carroll, Simon J
Published in PloS one (01.06.2016)
Published in PloS one (01.06.2016)
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Journal Article