Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1‑{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3‑b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)
Ugolini, Antonio, Kenigsberg, Mireille, Rak, Alexey, Vallée, Francois, Houtmann, Jacques, Lowinski, Maryse, Capdevila, Cécile, Khider, Jean, Albert, Eva, Martinet, Nathalie, Nemecek, Conception, Grapinet, Sandrine, Bacqué, Eric, Roesner, Manfred, Delaisi, Christine, Calvet, Loreley, Bonche, Fabrice, Semiond, Dorothée, Egile, Coumaran, Goulaouic, Hélène, Schio, Laurent
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Abstract 2911: SAR125844: a potent and selective ATP-competitive inhibitor of MET kinase
Schio, Laurent, Nemecek, Conception, Ugolini, Antonio, Wentzler, Sylvie, Grapinet, Sandrine, Khider, Jean, Albert, Eva, Dischamps, Nathalie, Gay, Frédéric, Sonnefraud, Véronique, Bacqué, Eric, Kenigsberg, Mireille, Goulaouic, Hélène, Dagallier, Anne, Vallée, François, Bonche, Fabrice, Lengauer, Christoph
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Improved antibacterial activities of coumarin antibiotics bearing 5′,5′-dialkylnoviose: biological activity of RU79115
Musicki, Branislav, Periers, Anne-Marie, Laurin, Patrick, Ferroud, Didier, Benedetti, Yannick, Lachaud, Sylvette, Chatreaux, Fabienne, Haesslein, Jean-Luc, Iltis, Alain, Pierre, Christine, Khider, Jean, Tessot, Nicole, Airault, Marlene, Demassey, Jacques, Dupuis-Hamelin, Claudine, Lassaigne, Patrice, Bonnefoy, Alain, Vicat, Pascale, Klich, Michel
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
Published in Bioorganic & medicinal chemistry letters (07.08.2000)
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1,3-Disubstituted-2-carboxy quinolones: highly potent and selective endothelin A receptor antagonists
Haesslein, Jean-Luc, Baholet, Isabelle, Fortin, Michel, Iltis, Alain, Khider, Jean, Periers, Anne Marie, Pierre, Christine, Vevert, Jean-Paul
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
Published in Bioorganic & medicinal chemistry letters (03.07.2000)
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