The Wnt Antagonist Secreted Frizzled-Related Protein-1 Is a Negative Regulator of Trabecular Bone Formation in Adult Mice
Bodine, Peter V. N, Zhao, Weiguang, Kharode, Yogendra P, Bex, Frederick J, Lambert, Andre-Jean, Goad, Mary Beth, Gaur, Tripti, Stein, Gary S, Lian, Jane B, Komm, Barry S
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2004)
Published in Molecular endocrinology (Baltimore, Md.) (01.05.2004)
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High Bone Mass in Mice Expressing a Mutant LRP5 Gene
Babij, Philip, Zhao, Weiguang, Small, Clayton, Kharode, Yogendra, Yaworsky, Paul J, Bouxsein, Mary L, Reddy, Padmalatha S, Bodine, Peter Vn, Robinson, John A, Bhat, Bheem, Marzolf, James, Moran, Robert A, Bex, Frederick
Published in Journal of bone and mineral research (01.06.2003)
Published in Journal of bone and mineral research (01.06.2003)
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Evaluation of an Estrogen Receptor-β Agonist in Animal Models of Human Disease
Harris, Heather A, Albert, Leo M, Leathurby, Yelena, Malamas, Michael S, Mewshaw, Richard E, Miller, Chris P, Kharode, Yogendra P, Marzolf, James, Komm, Barry S, Winneker, Richard C, Frail, Donald E, Henderson, Ruth A, Zhu, Yuan, Keith, James C
Published in Endocrinology (Philadelphia) (01.10.2003)
Published in Endocrinology (Philadelphia) (01.10.2003)
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Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1
Bodine, Peter V.N., Seestaller-Wehr, Laura, Kharode, Yogendra P., Bex, Frederick J., Komm, Barry S.
Published in Journal of cellular physiology (01.02.2007)
Published in Journal of cellular physiology (01.02.2007)
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(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate
Pelletier, Jeffrey C, Lundquist, Joseph T, Gilbert, Adam M, Alon, Nipa, Bex, Frederick J, Bhat, Bheem M, Bursavich, Mattew G, Coleburn, Valerie E, Felix, Luciana A, Green, Daniel M, Green, Paula, Hauze, Diane B, Kharode, Yogendra P, Lam, Ho-Sun, Lockhead, Susan R, Magolda, Ronald L, Matteo, Jeanne J, Mehlmann, John F, Milligan, Colleen, Murrills, Richard J, Pirrello, Jennifer, Selim, Sally, Sharp, Michael C, Unwalla, Ray J, Vera, Matthew D, Wrobel, Jay E, Yaworsky, Paul, Bodine, Peter V. N
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Systemically administered rhBMP-2 promotes MSC activity and reverses bone and cartilage loss in osteopenic mice
Turgeman, Gadi, Zilberman, Yoram, Zhou, Shuanhu, Kelly, Pam, Moutsatsos, Ioannis K., Kharode, Yogendra P., Borella, Luis E., Bex, Frederick J., Komm, Barry S., Bodine, Peter V.N., Gazit, Dan
Published in Journal of cellular biochemistry (2002)
Published in Journal of cellular biochemistry (2002)
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Osteogenic effects of a potent Src-over-Abl-selective kinase inhibitor in the mouse
Murrills, Richard J, Fukayama, Shoichi, Boschelli, Frank, Matteo, Jeanne J, Owens, Jane, Golas, Jennifer M, Patel, Dharmesh, Lane, Giovan, Liu, Yao-Bin, Carter, Laura, Jussif, Jason, Spaulding, Vikki, Wang, Yanong D, Boschelli, Diane H, McKew, John C, Li, X Jian, Lockhead, Susan, Milligan, Colleen, Kharode, Yogendra P, Diesl, Veronica, Bai, Yuchen, Follettie, Max, Bex, Frederick J, Komm, Barry, Bodine, Peter V N
Published in The Journal of pharmacology and experimental therapeutics (01.03.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2012)
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Semaphorin 3B Is a 1,25-Dihydroxyvitamin D3-Induced Gene in Osteoblasts that Promotes Osteoclastogenesis and Induces Osteopenia in Mice
Sutton, Amelia L. M, Zhang, Xiaoxue, Dowd, Diane R, Kharode, Yogendra P, Komm, Barry S, MacDonald, Paul N
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2008)
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2008)
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Journal Article
Identification of a PTH regulated gene selectively induced in vivo during PTH-mediated bone formation
Robinson, John A., Susulic, Vedrana, Liu, Yao-Bin, Taylor, Chanda, Hardenburg, Jill, Gironda, Virginia, Zhao, Weiguang, Kharode, Yogendra, McLarney, Sean, Bai, Yuchen, Malone, Daniel P., Murrills, Richard, Bex, Fred
Published in Journal of cellular biochemistry (01.08.2006)
Published in Journal of cellular biochemistry (01.08.2006)
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Journal Article
In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity
Murrills, Richard J., Matteo, Jeanne J., Samuel, Rachelle L., Andrews, Jennifer L., Bhat, Bheem M., Coleburn, Valerie E., Kharode, Yogendra P., Bex, Frederick J.
Published in Bone (New York, N.Y.) (01.12.2004)
Published in Bone (New York, N.Y.) (01.12.2004)
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Journal Article
Wnt/β-Catenin Signaling Is a Normal Physiological Response to Mechanical Loading in Bone
Robinson, John A., Chatterjee-Kishore, Moitreyee, Yaworsky, Paul J., Cullen, Diane M., Zhao, Weiguang, Li, Christine, Kharode, Yogendra, Sauter, Linda, Babij, Philip, Brown, Eugene L., Hill, Andrew A., Akhter, Mohammed P., Johnson, Mark L., Recker, Robert R., Komm, Barry S., Bex, Frederick J.
Published in The Journal of biological chemistry (20.10.2006)
Published in The Journal of biological chemistry (20.10.2006)
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Journal Article
The Pairing of a Selective Estrogen Receptor Modulator, Bazedoxifene, with Conjugated Estrogens as a New Paradigm for the Treatment of Menopausal Symptoms and Osteoporosis Prevention
Kharode, Yogendra, Bodine, Peter V. N, Miller, Christopher P, Lyttle, C. Richard, Komm, Barry S
Published in Endocrinology (Philadelphia) (01.12.2008)
Published in Endocrinology (Philadelphia) (01.12.2008)
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Journal Article
Semaphorin 3B Is a 1,25-Dihydroxyvitamin D sub(3)-Induced Gene in Osteoblasts that Promotes Osteoclastogenesis and Induces Osteopenia in Mice
Sutton, Amelia LM, Zhang, Xiaoxue, Dowd, Diane R, Kharode, Yogendra P, Komm, Barry S, MacDonald, Paul N
Published in Molecular endocrinology (Baltimore, Md.) (01.06.2008)
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Published in Molecular endocrinology (Baltimore, Md.) (01.06.2008)
Journal Article
Hit to lead studies on (hetero)arylpyrimidines—Agonists of the canonical Wnt-β-catenin cellular messaging system
Gilbert, Adam M., Bursavich, Matthew G., Alon, Nippa, Bhat, Bheem M., Bex, Frederick J., Cain, Michael, Coleburn, Valerie, Gironda, Virginia, Green, Paula, Hauze, Diane B., Kharode, Yogendra, Krishnamurthy, Girija, Kirisits, Matthew, Lam, Ho-Sun, Liu, Yao-Bin, Lombardi, Sabrina, Matteo, Jeanne, Murrills, Richard, Robinson, John A., Selim, Sally, Sharp, Michael, Unwalla, Raymond, Varadarajan, Usha, Zhao, Weiguang, Yaworsky, Paul J.
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
Hit to lead studies on (hetero)arylpyrimidines - Agonists of the canonical Wnt-b-catenin cellular messaging system
Gilbert, Adam M, Bursavich, Matthew G, Alon, Nippa, Bhat, Bheem M, Bex, Frederick J, Cain, Michael, Coleburn, Valerie, Gironda, Virginia, Green, Paula, Hauze, Diane B, Kharode, Yogendra, Krishnamurthy, Girija, Kirisits, Matthew, Lam, Ho-Sun, Liu, Yao-Bin, Lombardi, Sabrina, Matteo, Jeanne, Murrills, Richard, Robinson, John A, Selim, Sally, Sharp, Michael, Unwalla, Raymond, Varadarajan, Usha, Zhao, Weiguang, Yaworsky, Paul J
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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Journal Article
1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-ylmethanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate
PELLETIER, Jeffrey C, LUNDQUIST, Joseph T, GREEN, Paula, HAUZE, Diane B, KHARODE, Yogendra P, LAM, Ho-Sun, LOCKHEAD, Susan R, MAGOLDA, Ronald L, MATTEO, Jeanne J, MEHLMANN, John F, MILLIGAN, Colleen, MURRILLS, Richard J, GILBERT, Adam M, PIRRELLO, Jennifer, SELIM, Sally, SHARP, Michael C, UNWALLA, Ray J, VERA, Matthew D, WROBEL, Jay E, YAWORSKY, Paul, BODINE, Peter V. N, ALON, Nipa, BEX, Frederick J, BHAT, Bheem M, BURSAVICH, Mattew G, COLEBURN, Valerie E, FELIX, Luciana A, GREEN, Daniel M
Published in Journal of medicinal chemistry (2009)
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Published in Journal of medicinal chemistry (2009)
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