Midazolam Oxidation by Cytochrome P450 3A4 and Active-Site Mutants: an Evaluation of Multiple Binding Sites and of the Metabolic Pathway That Leads to Enzyme Inactivation
Khan, Kishore K, He, You Qun, Domanski, Tammy L, Halpert, James R
Published in Molecular pharmacology (01.03.2002)
Published in Molecular pharmacology (01.03.2002)
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Phenylalanine and Tryptophan Scanning Mutagenesis of CYP3A4 Substrate Recognition Site Residues and Effect on Substrate Oxidation and Cooperativity
Domanski, Tammy L, He, You-Ai, Khan, Kishore K, Roussel, Fabienne, Wang, Qinmi, Halpert, James R
Published in Biochemistry (Easton) (28.08.2001)
Published in Biochemistry (Easton) (28.08.2001)
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The Importance of SRS-1 Residues in Catalytic Specificity of Human Cytochrome P450 3A4
Roussel, Fabienne, Khan, Kishore K., Halpert, James R.
Published in Archives of biochemistry and biophysics (15.02.2000)
Published in Archives of biochemistry and biophysics (15.02.2000)
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TOPOLOGICAL CHANGES IN THE CYP3A4 ACTIVE SITE PROBED WITH PHENYLDIAZENE: EFFECT OF INTERACTION WITH NADPH-CYTOCHROME P450 REDUCTASE AND CYTOCHROME B5 AND OF SITE-DIRECTED MUTAGENESIS
Yamaguchi, Yoshitaka, Khan, Kishore K, He, You Ai, He, You Qun, Halpert, James R
Published in Drug metabolism and disposition (01.01.2004)
Published in Drug metabolism and disposition (01.01.2004)
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The reduction of ferryl myoglobin by phenols
Ravikanth, M, Khan, Kishore K, Mitra, S
Published in Proceedings of the Indian Academy of Sciences. Chemical sciences (01.06.1996)
Published in Proceedings of the Indian Academy of Sciences. Chemical sciences (01.06.1996)
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TOPOLOGICAL CHANGES IN THE CYP3A4 ACTIVE SITE PROBED WITH PHENYLDIAZENE: EFFECT OF INTERACTION WITH NADPH-CYTOCHROME P450 REDUCTASE AND CYTOCHROME B 5 AND OF SITE-DIRECTED MUTAGENESIS
Yamaguchi, Yoshitaka, Khan, Kishore K., He, You Ai, He, You Qun, Halpert, James R.
Published in Drug metabolism and disposition (01.01.2004)
Published in Drug metabolism and disposition (01.01.2004)
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Sequence Effects on DNA Stereodynamics: Conformational Behavior of d-GGTAGIACTACC Containing IA Mismatched Base Pairs
Chary, Kandala V. R, Khan, Kishore K, Rastogi, Vinit K, Govil, Girjesh, Howard, Frank B, Miles, H. Todd
Published in Journal of physical chemistry (1952) (01.09.1994)
Published in Journal of physical chemistry (1952) (01.09.1994)
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Identification and functional characterization of eight CYP3A4 protein variants
Eiselt, R, Domanski, T L, Zibat, A, Mueller, R, Presecan-Siedel, E, Hustert, E, Zanger, U M, Brockmoller, J, Klenk, H P, Meyer, U A, Khan, K K, He, Y A, Halpert, J R, Wojnowski, L
Published in Pharmacogenetics (London) (01.07.2001)
Published in Pharmacogenetics (London) (01.07.2001)
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