Neutrophil interactions with T cells, platelets, endothelial cells, and of course tumor cells
Segal, Brahm H., Giridharan, Thejaswini, Suzuki, Sora, Khan, ANM Nazmul H., Zsiros, Emese, Emmons, Tiffany R., Yaffe, Michael B., Gankema, Angela A. F., Hoogeboom, Mark, Goetschalckx, Ines, Matlung, Hanke L., Kuijpers, Taco W.
Published in Immunological reviews (01.03.2023)
Published in Immunological reviews (01.03.2023)
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Quantification of Early-Stage Myeloid-Derived Suppressor Cells in Cancer Requires Excluding Basophils
Khan, Anm Nazmul H, Emmons, Tiffany R, Wong, Jerry T, Alqassim, Emad, Singel, Kelly L, Mark, Jaron, Smith, Brandon E, Tario, Joseph D, Eng, Kevin H, Moysich, Kirsten B, Odunsi, Kunle, Abrams, Scott I, Segal, Brahm H
Published in Cancer immunology research (01.06.2020)
Published in Cancer immunology research (01.06.2020)
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Cytokine profiling of ascites at primary surgery identifies an interaction of tumor necrosis factor-α and interleukin-6 in predicting reduced progression-free survival in epithelial ovarian cancer
Kolomeyevskaya, Nonna, Eng, Kevin H, Khan, Anm Nazmul H, Grzankowski, Kassondra S, Singel, Kelly L, Moysich, Kirsten, Segal, Brahm H
Published in Gynecologic oncology (01.08.2015)
Published in Gynecologic oncology (01.08.2015)
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VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients
Khan, ANM Nazmul H., Emmons, Tiffany R., Magner, William J., Alqassim, Emad, Singel, Kelly L., Ricciuti, Jason, Eng, Kevin H., Odunsi, Kunle, Tomasi, Thomas B., Lee, Kelvin, Abrams, Scott I., Mesa, Circe, Segal, Brahm H.
Published in Cancer Immunology, Immunotherapy (01.10.2022)
Published in Cancer Immunology, Immunotherapy (01.10.2022)
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Mature neutrophils suppress T cell immunity in ovarian cancer microenvironment
Singel, Kelly L, Emmons, Tiffany R, Khan, Anm Nazmul H, Mayor, Paul C, Shen, Shichen, Wong, Jerry T, Morrell, Kayla, Eng, Kevin H, Mark, Jaron, Bankert, Richard B, Matsuzaki, Junko, Koya, Richard C, Blom, Anna M, McLeish, Kenneth R, Qu, Jun, Ram, Sanjay, Moysich, Kirsten B, Abrams, Scott I, Odunsi, Kunle, Zsiros, Emese, Segal, Brahm H
Published in JCI insight (07.03.2019)
Published in JCI insight (07.03.2019)
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Journal Article
Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer
Emmons, Tiffany R, Giridharan, Thejaswini, Singel, Kelly L, Khan, Anm Nazmul H, Ricciuti, Jason, Howard, Kaitlyn, Silva-Del Toro, Stephanie L, Debreceni, Ivy L, Aarts, Cathelijn E M, Brouwer, Mieke C, Suzuki, Sora, Kuijpers, Taco W, Jongerius, Ilse, Allen, Lee-Ann H, Ferreira, Viviana P, Schubart, Anna, Sellner, Holger, Eder, Jörg, Holland, Steven M, Ram, Sanjay, Lederer, James A, Eng, Kevin H, Moysich, Kirsten B, Odunsi, Kunle, Yaffe, Michael B, Zsiros, Emese, Segal, Brahm H
Published in Cancer immunology research (01.07.2021)
Published in Cancer immunology research (01.07.2021)
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Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer
Khan, Anm Nazmul H, Kolomeyevskaya, Nonna, Singel, Kelly L, Grimm, Melissa J, Moysich, Kirsten B, Daudi, Sayeema, Grzankowski, Kassondra S, Lele, Sashikant, Ylagan, Lourdes, Webster, Gill A, Abrams, Scott I, Odunsi, Kunle, Segal, Brahm H
Published in Oncotarget (10.05.2015)
Published in Oncotarget (10.05.2015)
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Journal Article
Neutrophils in the tumor microenvironment (TME) induce T cell non-responsiveness characterized by a shift from proliferation and activation to lipid transport pathways
Giridharan, Thejaswini, Suzuki, Sora, Khan, ANM Nazmul H., Stokolosa, Anna, Long, Mark D., Rosario, Spencer R., Emmons, Tiffany R., Yaffe, Michael B., Zsiros, Emese, Segal, Brahm H.
Published in The Journal of immunology (1950) (01.05.2023)
Published in The Journal of immunology (1950) (01.05.2023)
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Journal Article
Ovarian cancer ascites induces a T cell suppressive phenotype in mature neutrophils: a potential barrier to anti-tumor immunity
Singel, Kelly L, Khan, ANM Nazmul H, Moysich, Kirsten B, Odunsi, Kunle, Segal, Brahm H
Published in The Journal of immunology (1950) (01.05.2017)
Published in The Journal of immunology (1950) (01.05.2017)
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Journal Article
Ovarian cancer ascites-activated neutrophils suppress T cell proliferation in a contact-dependent mechanism
Singel, Kelly L, Khan, ANM Nazmul H, Emmons, Tiffany R, Mayor, Paul C, Moysich, Kirsten B, Odunsi, Kunle, Segal, Brahm H
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Pretreatment serum mitochondrial DNA (mtDNA) correlates with shorter progression-free and overall survival in patients with advanced ovarian cancer (OC)
Grzankowski, Kassondra S., Khan, Anm Nazmul H., Eng, Kevin H., Grimm, Melissa, Singel, Kelly L., Kolomeyevskaya, Nonna, Moysich, Kirsten B., Odunsi, Kunle, Segal, Brahm H.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Effect of cell-free ascites containing mitochondrial DNA (mtDNA) from ovarian cancer (OC) patients on human neutrophils and neutrophil extracellular traps (NETs)
Grzankowski, Kassondra S., Khan, Anm Nazmul H., Grimm, Melissa, Hylander, Bonnie, Singel, Kelly L., Moysich, Kirsten B., Kolomeyevskaya, Nonna, Odunsi, Kunle, Segal, Brahm H.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
RNA editing enzyme APOBEC3A promotes pro-inflammatory (M1) macrophage polarization
Alqassim, Emad Y, Sharma, Shraddha, Anm Nazmul H Khan, Emmons, Tiffany, Cortes-Gomez, Eduardo, Singel, Kelly, Jaron, Mark, Davidson, Bruce A, Mcgray, Aj Robert, Liu, Qian, Litchy, Brian D, Moysich, Kirsten, Wang, Jianmin, Odunsi, Kunle, Segal, Brahm H, Baysal, Bora E
Published in bioRxiv (18.04.2020)
Published in bioRxiv (18.04.2020)
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