MOLECULAR MECHANISMS OF MAMMALIAN DNA REPAIR AND THE DNA DAMAGE CHECKPOINTS
Sancar, Aziz, Lindsey-Boltz, Laura A, Ünsal-Kaçmaz, Keziban, Linn, Stuart
Published in Annual review of biochemistry (01.01.2004)
Published in Annual review of biochemistry (01.01.2004)
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Journal Article
The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
Unsal-Kaçmaz, Keziban, Chastain, Paul D, Qu, Ping-Ping, Minoo, Parviz, Cordeiro-Stone, Marila, Sancar, Aziz, Kaufmann, William K
Published in Molecular and Cellular Biology (01.04.2007)
Published in Molecular and Cellular Biology (01.04.2007)
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Journal Article
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
Kemp, Michael G., Akan, Zafer, Yilmaz, Seçil, Grillo, Mary, Smith-Roe, Stephanie L., Kang, Tae-Hong, Cordeiro-Stone, Marila, Kaufmann, William K., Abraham, Robert T., Sancar, Aziz, Ünsal-Kaçmaz, Keziban
Published in The Journal of biological chemistry (28.05.2010)
Published in The Journal of biological chemistry (28.05.2010)
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Journal Article
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Kim, Jiyeon, Hu, Zeping, Cai, Ling, Li, Kailong, Choi, Eunhee, Faubert, Brandon, Bezwada, Divya, Rodriguez-Canales, Jaime, Villalobos, Pamela, Lin, Yu-Fen, Ni, Min, Huffman, Kenneth E, Girard, Luc, Byers, Lauren A, Unsal-Kacmaz, Keziban, Peña, Christopher G, Heymach, John V, Wauters, Els, Vansteenkiste, Johan, Castrillon, Diego H, Chen, Benjamin P C, Wistuba, Ignacio, Lambrechts, Diether, Xu, Jian, Minna, John D, DeBerardinis, Ralph J
Published in Nature (London) (01.06.2017)
Published in Nature (London) (01.06.2017)
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Journal Article
Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase
Emmanuel, Natasha, Ragunathan, Shoba, Shan, Qin, Wang, Fang, Giannakou, Andreas, Huser, Nanni, Jin, Guixian, Myers, Jeremy, Abraham, Robert T., Unsal-Kacmaz, Keziban
Published in Cell reports (Cambridge) (27.06.2017)
Published in Cell reports (Cambridge) (27.06.2017)
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Journal Article
Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
DOHERTY, Joanne R, CHUNYING YANG, TORTOSA, Mariola, GENAU, Heide Marika, ROUNBEHLER, Robert J, YUNQI LU, DANG, Chi V, KUMAR, K. Ganesh, BUTLER, Andrew A, BANNISTER, Thomas D, HOOPER, Andrea T, UNSAL-KACMAZ, Keziban, SCOTT, Kristen E. N, ROUSH, William R, CLEVELAND, John L, CAMERON, Michael D, FALLAHI, Mohammad, WEIMIN LI, HALL, Mark A, AMELIO, Antonio L, MISHRA, Jitendra K, FANGZHENG LI
Published in Cancer research (Chicago, Ill.) (01.02.2014)
Published in Cancer research (Chicago, Ill.) (01.02.2014)
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Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing
Wang, Li, Sfakianos, John P, Beaumont, Kristin G, Akturk, Guray, Horowitz, Amir, Sebra, Robert P, Farkas, Adam M, Gnjatic, Sacha, Hake, Austin, Izadmehr, Sudeh, Wiklund, Peter, Oh, William K, Szabo, Peter M, Wind-Rotolo, Megan, Unsal-Kacmaz, Keziban, Yao, Xin, Schadt, Eric, Sharma, Padmanee, Bhardwaj, Nina, Zhu, Jun, Galsky, Matthew D
Published in Clinical cancer research (01.08.2021)
Published in Clinical cancer research (01.08.2021)
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Journal Article
Preferential Binding of ATR Protein to UV-Damaged DNA
Ünsal-Kaçmaz, Keziban, Makhov, Alexander M., Griffith, Jack D., Sancar, Aziz
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2002)
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Journal Article
Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors
Falk, Matthew D, Liu, Wei, Bolaños, Ben, Unsal-Kacmaz, Keziban, Klippel, Anke, Grant, Stephan, Brooun, Alexei, Timofeevski, Sergei
Published in Bioscience reports (01.04.2014)
Published in Bioscience reports (01.04.2014)
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Journal Article
First results from the phase 3 CheckMate 274 trial of adjuvant nivolumab vs placebo in patients who underwent radical surgery for high-risk muscle-invasive urothelial carcinoma (MIUC)
Bajorin, Dean F., Witjes, Johannes Alfred, Gschwend, Jürgen, Schenker, Michael, Valderrama, Begoña P., Tomita, Yoshihiko, Bamias, Aristotelis, Lebret, Thierry, Shariat, Shahrokh, Park, Se Hoon, Ye, Dingwei, Agerbaek, Mads, Collette, Sandra, Unsal-Kacmaz, Keziban, Zardavas, Dimitrios, Koon, Henry B., Galsky, Matt D.
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
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Journal Article
Disease-free Survival Analysis for Patients with High-risk Muscle-invasive Urothelial Carcinoma from the Randomized CheckMate 274 Trial by PD-L1 Combined Positive Score and Tumor Cell Score
Galsky, Matthew D., Bajorin, Dean F., Witjes, Johannes Alfred, Gschwend, Jürgen E., Tomita, Yoshihiko, Nasroulah, Federico, Li, Jun, Collette, Sandra, Valderrama, Begoña P., Grimm, Marc-Oliver, Appleman, Leonard, Gravis, Gwenaelle, Necchi, Andrea, Ye, Dingwei, Stenner, Frank, Wind-Rotolo, Megan, Zhang, Joshua, Ünsal-Kaçmaz, Keziban
Published in European urology (01.05.2023)
Published in European urology (01.05.2023)
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Journal Article
Adjuvant nivolumab versus placebo following radical surgery for high-risk muscle-invasive urothelial carcinoma: a subgroup analysis of Japanese patients enrolled in the phase 3 CheckMate 274 trial
Tomita, Yoshihiko, Kobayashi, Ko, Kimura, Go, Oya, Mototsugu, Uemura, Hirotsugu, Nishiyama, Hiroyuki, Galsky, Matthew D, Nasroulah, Federico, Collette, Sandra, Broughton, Edward, Ünsal-Kaçmaz, Keziban, Kamisuki, Yukinori, Bajorin, Dean F
Published in Japanese journal of clinical oncology (06.01.2023)
Published in Japanese journal of clinical oncology (06.01.2023)
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Journal Article
BMS-986158, a Small Molecule Inhibitor of the Bromodomain and Extraterminal Domain Proteins, in Patients with Selected Advanced Solid Tumors: Results from a Phase 1/2a Trial
Hilton, John, Cristea, Mihaela, Postel-Vinay, Sophie, Baldini, Capucine, Voskoboynik, Mark, Edenfield, William, Shapiro, Geoffrey I., Cheng, Michael L., Vuky, Jacqueline, Corr, Bradley, Das, Sharmila, Apfel, Abraham, Xu, Ke, Kozicki, Martin, Ünsal-Kaçmaz, Keziban, Hammell, Amy, Wang, Guan, Ravindran, Palanikumar, Kollia, Georgia, Esposito, Oriana, Coker, Shodeinde, Diamond, Jennifer R.
Published in Cancers (23.08.2022)
Published in Cancers (23.08.2022)
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Journal Article
Coupling of Human Circadian and Cell Cycles by the Timeless Protein
Ünsal-Kaçmaz, Keziban, Mullen, Thomas E., Kaufmann, William K., Sancar, Aziz
Published in Molecular and Cellular Biology (01.04.2005)
Published in Molecular and Cellular Biology (01.04.2005)
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Journal Article
Nivolumab plus rucaparib for metastatic castration-resistant prostate cancer: results from the phase 2 CheckMate 9KD trial
Fizazi, Karim, Retz, Margitta, Petrylak, Daniel P, Goh, Jeffrey C, Perez-Gracia, Jose, Lacombe, Louis, Zschäbitz, Stefanie, Burotto, Mauricio, Mahammedi, Hakim, Gravis, Gwenaelle, Bastos, Diogo Assed, McCune, Steven L, Vázquez Limón, Juan Carlos, Kwan, Edmond M, Castellano, Daniel, Fléchon, Aude, Saad, Fred, Grimm, Marc-Oliver, Shaffer, David R, Armstrong, Andrew J, Bhagavatheeswaran, Prabhu, Amin, Neha P, Ünsal-Kaçmaz, Keziban, Wang, Xuya, Li, Jun, Loehr, Andrea, Pachynski, Russell K
Published in Journal for immunotherapy of cancer (01.08.2022)
Published in Journal for immunotherapy of cancer (01.08.2022)
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Journal Article
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
Heffernan, Timothy P., Ünsal-Kaçmaz, Keziban, Heinloth, Alexandra N., Simpson, Dennis A., Paules, Richard S., Sancar, Aziz, Cordeiro-Stone, Marila, Kaufmann, William K.
Published in The Journal of biological chemistry (30.03.2007)
Published in The Journal of biological chemistry (30.03.2007)
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Journal Article
Ubiquitylation of Proliferating Cell Nuclear Antigen and Recruitment of Human DNA Polymerase η
Nikolaishvili-Feinberg, Nana, Jenkins, G. Scott, Nevis, Kathleen R, Staus, Dean P, Scarlett, Cameron O, Ünsal-Kaçmaz, Keziban, Kaufmann, William K, Cordeiro-Stone, Marila
Published in Biochemistry (Easton) (01.04.2008)
Published in Biochemistry (Easton) (01.04.2008)
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Journal Article
Nivolumab plus docetaxel in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer: results from the phase II CheckMate 9KD trial
Fizazi, Karim, González Mella, Pablo, Castellano, Daniel, Minatta, Jose N., Rezazadeh Kalebasty, Arash, Shaffer, David, Vázquez Limón, Juan C., Sánchez López, Héctor M., Armstrong, Andrew J., Horvath, Lisa, Bastos, Diogo A., Amin, Neha P., Li, Jia, Unsal-Kacmaz, Keziban, Retz, Margitta, Saad, Fred, Petrylak, Daniel P., Pachynski, Russell K.
Published in European journal of cancer (1990) (01.01.2022)
Published in European journal of cancer (1990) (01.01.2022)
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Complementary detection of genomic alterations in metastatic castration-resistant prostate cancer (mCRPC) from CheckMate 9KD through analyses of tumor tissue and plasma DNA
Sausen, Mark, Baden, Jonathan F., Kalinava, Natallia, Wang, Xuya, Li, Jun, Anguiano, Esperanza, Unsal-Kacmaz, Keziban, Wind-Rotolo, Megan, Quinn, Katie, Green, George
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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