Repeat expansions confer WRN dependence in microsatellite-unstable cancers
van Wietmarschen, Niek, Sridharan, Sriram, Nathan, William J., Tubbs, Anthony, Chan, Edmond M., Callen, Elsa, Wu, Wei, Belinky, Frida, Tripathi, Veenu, Wong, Nancy, Foster, Kyla, Noorbakhsh, Javad, Garimella, Kiran, Cruz-Migoni, Abimael, Sommers, Joshua A., Huang, Yongqing, Borah, Ashir A., Smith, Jonathan T., Kalfon, Jeremie, Kesten, Nikolas, Fugger, Kasper, Walker, Robert L., Dolzhenko, Egor, Eberle, Michael A., Hayward, Bruce E., Usdin, Karen, Freudenreich, Catherine H., Brosh, Robert M., West, Stephen C., McHugh, Peter J., Meltzer, Paul S., Bass, Adam J., Nussenzweig, André
Published in Nature (London) (08.10.2020)
Published in Nature (London) (08.10.2020)
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FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues
Font-Tello, Alba, Kesten, Nikolas, Xie, Yingtian, Taing, Len, Varešlija, Damir, Young, Leonie S., Hamid, Anis A., Van Allen, Eliezer M., Sweeney, Christopher J., Gjini, Evisa, Lako, Ana, Hodi, F. Steven, Bellmunt, Joaquim, Brown, Myles, Cejas, Paloma, Long, Henry W.
Published in Nature protocols (01.08.2020)
Published in Nature protocols (01.08.2020)
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Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence
Wu, Zhong, Zhou, Jin, Zhang, Xiaoyang, Zhang, Zhouwei, Xie, Yingtian, Liu, Jie bin, Ho, Zandra V., Panda, Arpit, Qiu, Xintao, Cejas, Paloma, Cañadas, Israel, Akarca, Fahire Goknur, McFarland, James M., Nagaraja, Ankur K., Goss, Louisa B., Kesten, Nikolas, Si, Longlong, Lim, Klothilda, Liu, Yanli, Zhang, Yanxi, Baek, Ji Yeon, Liu, Yang, Patil, Deepa T., Katz, Jonathan P., Hai, Josephine, Bao, Chunyang, Stachler, Matthew, Qi, Jun, Ishizuka, Jeffrey J., Nakagawa, Hiroshi, Rustgi, Anil K., Wong, Kwok-Kin, Meyerson, Matthew, Barbie, David A., Brown, Myles, Long, Henry, Bass, Adam J.
Published in Nature genetics (01.06.2021)
Published in Nature genetics (01.06.2021)
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CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-seq Analysis
Qiu, Xintao, Feit, Avery S., Feiglin, Ariel, Xie, Yingtian, Kesten, Nikolas, Taing, Len, Perkins, Joseph, Gu, Shengqing, Li, Yihao, Cejas, Paloma, Zhou, Ningxuan, Jeselsohn, Rinath, Brown, Myles, Shirley Liu, X., Long, Henry W.
Published in Genomics, proteomics & bioinformatics (01.08.2021)
Published in Genomics, proteomics & bioinformatics (01.08.2021)
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Journal Article
CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity
Watt, April C, Cejas, Paloma, DeCristo, Molly J, Metzger-Filho, Otto, Lam, Enid Y N, Qiu, Xintao, BrinJones, Haley, Kesten, Nikolas, Coulson, Rhiannon, Font-Tello, Alba, Lim, Klothilda, Vadhi, Raga, Daniels, Veerle W, Montero, Joan, Taing, Len, Meyer, Clifford A, Gilan, Omer, Bell, Charles C, Korthauer, Keegan D, Giambartolomei, Claudia, Pasaniuc, Bogdan, Seo, Ji-Heui, Freedman, Matthew L, Ma, Cynthia, Ellis, Matthew J, Krop, Ian, Winer, Eric, Letai, Anthony, Brown, Myles, Dawson, Mark A, Long, Henry W, Zhao, Jean J, Goel, Shom
Published in Nature cancer (01.01.2021)
Published in Nature cancer (01.01.2021)
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Abstract 3662: FiTAc-seq: Fixed-Tissue ChIP-seq for H3K27Ac profiling and super-enhancer analysis on FFPE tissues
Font-Tello, Alba, Kesten, Nikolas, Xie, Yingtian, Taing, Len, Bellmunt, Joaquim, Brown, Myles, Cejas, Paloma, Long, Henry
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
ERG-Mediated Coregulator Complex Formation Maintains Androgen Receptor Signaling in Prostate Cancer
Shah, Neel, Kesten, Nikolas, Font-Tello, Alba, Chang, Matthew E K, Vadhi, Raga, Lim, Klothilda, Flory, Mark R, Cejas, Paloma, Mohammed, Hisham, Long, Henry W, Brown, Myles
Published in Cancer research (Chicago, Ill.) (01.11.2020)
Published in Cancer research (Chicago, Ill.) (01.11.2020)
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Distinct oncogenic signatures in malignant PEComa and leiomyosarcoma identified by integrative RNA-seq and H3K27ac ChIP-seq analysis
Giannikou, Krinio, Azim, Ahmad-Abdel, Adib, Elio, Schaefer, Inga-Marie, Kesten, Nikolas, Taing, Len, Zhu, Zachary, Hornick, Jason, Hirsch, Michelle S., Long, Henry, Wagner, Andrew J., Hemming, Matthew Louis, Kwiatkowski, David J.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer
Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C, Guerriero, Jennifer L, Qi, Jun, Long, Henry W, Polyak, Kornelia
Published in Molecular cancer therapeutics (01.11.2023)
Published in Molecular cancer therapeutics (01.11.2023)
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Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer
Guarducci, Cristina, Nardone, Agostina, Russo, Douglas, Nagy, Zsuzsanna, Heraud, Capucine, Grinshpun, Albert, Zhang, Qi, Freelander, Allegra, Leventhal, Mathew Joseph, Feit, Avery, Cohen Feit, Gabriella, Feiglin, Ariel, Liu, Weihan, Hermida-Prado, Francisco, Kesten, Nikolas, Ma, Wen, De Angelis, Carmine, Morlando, Antonio, O'Donnell, Madison, Naumenko, Sergey, Huang, Shixia, Nguyen, Quang-Dé, Huang, Ying, Malorni, Luca, Bergholz, Johann S, Zhao, Jean J, Fraenkel, Ernest, Lim, Elgene, Schiff, Rachel, Shapiro, Geoffrey I, Jeselsohn, Rinath
Published in Clinical cancer research (01.05.2024)
Published in Clinical cancer research (01.05.2024)
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Abstract PO-010: Kidney angiomyolipomas are defined by a unique transcriptomic profile and H3K27ac chromatin state
Giannikou, Krinio, Probst, Clemens K., Zarei, Mahsa, Qiu, Xintao, Duarte, Melissa, Kesten, Nikolas, Hebert, Zachary, Vadhi, Raga, Font-Tello, Alba, Cejas, Paloma, Yoon, Charles H., Wu, Chin-Lee, Brown, Myles, Henske, Elizabeth P., Long, Henry, Kwiatkowski, David J.
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
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Abstract PR06: Dissecting mechanisms of replication fork stabilization in patient-derived high-grade serous organoid cultures and their impact on therapeutic sensitivity and the immune-tumor interaction
Hill, Sarah J., Lizotte, Patrick, Kesten, Nikolas, Horowitz, Neil S., Muto, Michael G., Worley, Michael J., Feltmate, Colleen M., Berkowitz, Ross S., Long, Henry, Matulonis, Ursula A., Crum, Christopher P., Brown, Myles, D'Andrea, Alan D.
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Abstract PR014: Cytokine mediated epigenetic reprogramming of CRC primary tumors drives liver metastasis
Rennhack, Jonathan, Dwivedi, Arika, Wu, Nathan, Shim, Brian, Font-Tello, Alba, Kesten, Nikolas, Aguirre, Andrew, Long, Henry, Ng, Kimmie, Hahn, William C.
Published in Cancer research (Chicago, Ill.) (15.01.2023)
Published in Cancer research (Chicago, Ill.) (15.01.2023)
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Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1–AKT–p53 Interactions
Lynch, Katherine N., Liu, Joyce F., Kesten, Nikolas, Chow, Kin-Hoe, Shetty, Aniket, He, Ruiyang, Afreen, Mosammat Faria, Yuan, Liping, Matulonis, Ursula A., Growdon, Whitfield B., Muto, Michael G., Horowitz, Neil S., Feltmate, Colleen M., Worley, Michael J., Berkowitz, Ross S., Crum, Christopher P., Rueda, Bo R., Hill, Sarah J.
Published in Cancers (03.05.2021)
Published in Cancers (03.05.2021)
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CoBRA: Containerized Bioinformatics workflow for Reproducible ChIP/ATAC-seq Analysis - from differential peak calling to pathway analysis
Qiu, Xintao, Feit, Avery S, Feiglin, Ariel, Xie, Yingtian, Kesten, Nikolas, Taing, Len, Perkins, Joseph, Zhou, Ningxuan, Gu, Shengqing, Li, Yihao, Cejas, Paloma, Jeselsohn, Rinath, Brown, Myles, X Shirley Liu, Long, Henry W
Published in bioRxiv (08.11.2020)
Published in bioRxiv (08.11.2020)
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