Exome sequencing and analysis of 454,787 UK Biobank participants
Backman, Joshua D., Li, Alexander H., Marcketta, Anthony, Sun, Dylan, Mbatchou, Joelle, Kessler, Michael D., Benner, Christian, Liu, Daren, Locke, Adam E., Balasubramanian, Suganthi, Yadav, Ashish, Banerjee, Nilanjana, Gillies, Christopher E., Damask, Amy, Liu, Simon, Bai, Xiaodong, Hawes, Alicia, Maxwell, Evan, Gurski, Lauren, Watanabe, Kyoko, Kosmicki, Jack A., Rajagopal, Veera, Mighty, Jason, Jones, Marcus, Mitnaul, Lyndon, Stahl, Eli, Coppola, Giovanni, Jorgenson, Eric, Habegger, Lukas, Salerno, William J., Shuldiner, Alan R., Lotta, Luca A., Overton, John D., Cantor, Michael N., Reid, Jeffrey G., Yancopoulos, George, Kang, Hyun M., Marchini, Jonathan, Baras, Aris, Abecasis, Gonçalo R., Ferreira, Manuel A. R.
Published in Nature (London) (25.11.2021)
Published in Nature (London) (25.11.2021)
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Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire
Harris, Daniel N., Song, Wei, Shetty, Amol C., Levano, Kelly S., Cáceres, Omar, Padilla, Carlos, Borda, Víctor, Tarazona, David, Trujillo, Omar, Sanchez, Cesar, Kessler, Michael D., Galarza, Marco, Capristano, Silvia, Montejo, Harrison, Flores-Villanueva, Pedro O., Tarazona-Santos, Eduardo, O’Connor, Timothy D., Guio, Heinner
Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (10.07.2018)
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Ten quick tips for deep learning in biology
Lee, Benjamin D, Gitter, Anthony, Greene, Casey S, Raschka, Sebastian, Maguire, Finlay, Titus, Alexander J, Kessler, Michael D, Lee, Alexandra J, Chevrette, Marc G, Stewart, Paul Allen, Britto-Borges, Thiago, Cofer, Evan M, Yu, Kun-Hsing, Carmona, Juan Jose, Fertig, Elana J, Kalinin, Alexandr A, Signal, Brandon, Lengerich, Benjamin J, Triche, Jr, Timothy J, Boca, Simina M
Published in PLoS computational biology (01.03.2022)
Published in PLoS computational biology (01.03.2022)
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Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences
Kessler, Michael D., Bateman, Nicholas W., Conrads, Thomas P., Maxwell, George L., Dunning Hotopp, Julie C., O’Connor, Timothy D.
Published in Cancer (15.06.2019)
Published in Cancer (15.06.2019)
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Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors
Davis-Marcisak, Emily F, Fitzgerald, Allison A, Kessler, Michael D, Danilova, Ludmila, Jaffee, Elizabeth M, Zaidi, Neeha, Weiner, Louis M, Fertig, Elana J
Published in Genome medicine (11.08.2021)
Published in Genome medicine (11.08.2021)
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Oxaliplatin-Induced Peripheral Neuropathy and Identification of Unique Severity Groups in Colorectal Cancer
Griffith, Kathleen A., Zhu, Shijun, Johantgen, Meg, Kessler, Michael D., Renn, Cynthia, Beutler, Andreas S., Kanwar, Rahul, Ambulos, Nicholas, Cavaletti, Guido, Bruna, Jordi, Briani, Chiara, Argyriou, Andreas A., Kalofonos, Haralabos P., Yerges-Armstrong, Laura M., Dorsey, Susan G.
Published in Journal of pain and symptom management (01.11.2017)
Published in Journal of pain and symptom management (01.11.2017)
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Journal Article
Common and rare variant associations with clonal haematopoiesis phenotypes
Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric
Published in Nature (London) (08.12.2022)
Published in Nature (London) (08.12.2022)
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Journal Article
De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population
Kessler, Michael D., Loesch, Douglas P., Perry, James A., Heard-Costa, Nancy L., Taliun, Daniel, Cade, Brian E., Wang, Heming, Daya, Michelle, Ziniti, John, Datta, Soma, Celedón, Juan C., Soto-Quiros, Manuel E., Avila, Lydiana, Weiss, Scott T., Barnes, Kathleen, Redline, Susan S., Vasan, Ramachandran S., Johnson, Andrew D., Mathias, Rasika A., Hernandez, Ryan, Wilson, James G., Nickerson, Deborah A., Abecasis, Goncalo, Browning, Sharon R., Zöllne, Sebastian, O’Connell, Jeffrey R., Mitchell, Braxton D., O’Connor, Timothy D.
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2020)
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Journal Article
The Evolution of Polymorphic Hybrid Incompatibilities in House Mice
Larson, Erica L, Vanderpool, Dan, Sarver, Brice A J, Callahan, Colin, Keeble, Sara, Provencio, Lorraine L, Kessler, Michael D, Stewart, Vanessa, Nordquist, Erin, Dean, Matthew D, Good, Jeffrey M
Published in Genetics (Austin) (01.07.2018)
Published in Genetics (Austin) (01.07.2018)
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Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia
Kogan, Aksinija A, Topper, Michael J, Dellomo, Anna J, Stojanovic, Lora, McLaughlin, Lena J, Creed, T Michael, Eberly, Christian L, Kingsbury, Tami J, Baer, Maria R, Kessler, Michael D, Baylin, Stephen B, Rassool, Feyruz V
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2022)
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Journal Article
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets
Erbe, Rossin, Kessler, Michael D, Favorov, Alexander V, Easwaran, Hariharan, Gaykalova, Daria A, Fertig, Elana J
Published in Nucleic acids research (09.07.2020)
Published in Nucleic acids research (09.07.2020)
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Journal Article
Evolutionary history of modern Samoans
Harris, Daniel N., Kessler, Michael D., Shetty, Amol C., Weeks, Daniel E., Minster, Ryan L., Browning, Sharon, Cochrane, Ethan E., Deka, Ranjan, Hawley, Nicola L., Reupena, Muagututi‘a Sefuiva, Naseri, Take, McGarvey, Stephen T., O’Connor, Timothy D.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2020)
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Journal Article
Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry
Kessler, Michael D., Yerges-Armstrong, Laura, Taub, Margaret A., Shetty, Amol C., Maloney, Kristin, Jeng, Linda Jo Bone, Ruczinski, Ingo, Levin, Albert M., Williams, L. Keoki, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., O’Connor, Timothy D.
Published in Nature communications (11.10.2016)
Published in Nature communications (11.10.2016)
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Journal Article
Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes
Kessler, Michael D., Damask, Amy, O’Keeffe, Sean, Banerjee, Nilanjana, Li, Dadong, Watanabe, Kyoko, Marketta, Anthony, Van Meter, Michael, Semrau, Stefan, Horowitz, Julie, Tang, Jing, Kosmicki, Jack A., Rajagopal, Veera M., Zou, Yuxin, Houvras, Yariv, Ghosh, Arkopravo, Gillies, Christopher, Mbatchou, Joelle, White, Ryan R., Verweij, Niek, Bovijn, Jonas, Parikshak, Neelroop N., LeBlanc, Michelle G., Jones, Marcus, Glass, David J., Lotta, Luca A., Cantor, Michael N., Atwal, Gurinder S., Locke, Adam E., Ferreira, Manuel A. R., Deering, Raquel, Paulding, Charles, Shuldiner, Alan R., Thurston, Gavin, Ferrando, Adolfo A., Salerno, Will, Reid, Jeffrey G., Overton, John D., Marchini, Jonathan, Kang, Hyun M., Baras, Aris, Abecasis, Gonçalo R., Jorgenson, Eric
Published in Nature (London) (02.03.2023)
Published in Nature (London) (02.03.2023)
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Journal Article
Improving Cancer Detection and Treatment with Liquid Biopsies and ptDNA
Kessler, Michael D, Pawar, Nisha R, Martin, Stuart S, Antalis, Toni M, O'Connor, Timothy D
Published in Trends in cancer (01.09.2018)
Published in Trends in cancer (01.09.2018)
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Journal Article
Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry
Bateman, Nicholas W., Tarney, Christopher M., Abulez, Tamara S., Hood, Brian L., Conrads, Kelly A., Zhou, Ming, Soltis, Anthony R., Teng, Pang-Ning, Jackson, Amanda, Tian, Chunqiao, Dalgard, Clifton L., Wilkerson, Matthew D., Kessler, Michael D., Goecker, Zachary, Loffredo, Jeremy, Shriver, Craig D., Hu, Hai, Cote, Michele, Parker, Glendon J., Segars, James, Al-Hendy, Ayman, Risinger, John I., Phippen, Neil T., Casablanca, Yovanni, Darcy, Kathleen M., Maxwell, G. Larry, Conrads, Thomas P., O'Connor, Timothy D.
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
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Journal Article
A deep catalog of protein-coding variation in 985,830 individuals
Sun, Kathie Y, Bai, Xiaodong, Chen, Siying, Bao, Suying, Kapoor, Manav, Zhang, Chuanyi, Backman, Joshua, Joseph, Tyler, Maxwell, Evan, Mitra, George, Gorovits, Alexander, Mansfield, Adam, Boutkov, Boris, Gokhale, Sujit, Habegger, Lukas, Marcketta, Anthony, Locke, Adam, Kessler, Michael D, Sharma, Deepika, Staples, Jeffrey, Bovijn, Jonas, Gelfman, Sahar, Gioia, Alessandro Di, Rajagopal, Veera, Lopez, Alexander, Varela, Jennifer Rico, Alegre, Jesus, Berumen, Jaime, Tapia-Conyer, Roberto, Kuri-Morales, Pablo, Torres, Jason, Emberson, Jonathan, Collins, Rory, Cantor, Michael, Thornton, Timothy, Kang, Hyun Min, Overton, John, Shuldiner, Alan R, Cremona, M Laura, Nafde, Mona, Baras, Aris, Abecasis, Goncalo, Marchini, Jonathan, Reid, Jeffrey G, Salerno, William, Balasubramanian, Suganthi
Published in bioRxiv (02.11.2023)
Published in bioRxiv (02.11.2023)
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Journal Article
The placebo effect: From concepts to genes
Colagiuri, B, Schenk, L.A, Kessler, M.D, Dorsey, S.G, Colloca, L
Published in Neuroscience (29.10.2015)
Published in Neuroscience (29.10.2015)
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