Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab
Krejcik, Jakub, Frerichs, Kris A, Nijhof, Inger S, van Kessel, Berris, van Velzen, Jeroen F, Bloem, Andries C, Broekmans, Marloes E C, Zweegman, Sonja, van Meerloo, Johan, Musters, René J P, Poddighe, Pino J, Groen, Richard W J, Chiu, Christopher, Plesner, Torben, Lokhorst, Henk M, Sasser, A Kate, Mutis, Tuna, van de Donk, Niels W C J
Published in Clinical cancer research (15.12.2017)
Published in Clinical cancer research (15.12.2017)
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Impact of Fc gamma receptor polymorphisms on efficacy and safety of daratumumab in relapsed/refractory multiple myeloma
Donk, Niels W. C. J., Casneuf, Tineke, Di Cara, Alessandro, Parren, Paul W., Zweegman, Sonja, Kessel, Berris, Lokhorst, Henk M., Usmani, Saad Z., Lonial, Sagar, Richardson, Paul G., Chiu, Christopher, Mutis, Tuna, Nijhof, Inger S., Sasser, A. Kate
Published in British journal of haematology (01.02.2019)
Published in British journal of haematology (01.02.2019)
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CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma
Nijhof, Inger S., Casneuf, Tineke, van Velzen, Jeroen, van Kessel, Berris, Axel, Amy E., Syed, Khaja, Groen, Richard W.J., van Duin, Mark, Sonneveld, Pieter, Minnema, Monique C., Zweegman, Sonja, Chiu, Christopher, Bloem, Andries C., Mutis, Tuna, Lokhorst, Henk M., Sasser, A.Kate, van de Donk, Niels W.C.J.
Published in Blood (18.08.2016)
Published in Blood (18.08.2016)
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DuoHexaBody-CD37®, a novel biparatopic CD37 antibody with enhanced Fc-mediated hexamerization as a potential therapy for B-cell malignancies
Oostindie, Simone C., van der Horst, Hilma J., Kil, Laurens P., Strumane, Kristin, Overdijk, Marije B., van den Brink, Edward N., van den Brakel, Jeroen H. N., Rademaker, Hendrik J., van Kessel, Berris, van den Noort, Juliette, Chamuleau, Martine E. D., Mutis, Tuna, Lindorfer, Margaret A., Taylor, Ronald P., Schuurman, Janine, Parren, Paul W. H. I., Beurskens, Frank J., Breij, Esther C. W.
Published in Blood cancer journal (New York) (28.04.2020)
Published in Blood cancer journal (New York) (28.04.2020)
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Preclinical Evidence for the Therapeutic Potential of CD38-Targeted Immuno-Chemotherapy in Multiple Myeloma Patients Refractory to Lenalidomide and Bortezomib
Nijhof, Inger S, Groen, Richard W J, Noort, Willy A, van Kessel, Berris, de Jong-Korlaar, Regina, Bakker, Joost, van Bueren, Jeroen J L, Parren, Paul W H I, Lokhorst, Henk M, van de Donk, Niels W C J, Martens, Anton C M, Mutis, Tuna
Published in Clinical cancer research (15.06.2015)
Published in Clinical cancer research (15.06.2015)
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Preclinical Activity of JNJ-7957, a Novel BCMA×CD3 Bispecific Antibody for the Treatment of Multiple Myeloma, Is Potentiated by Daratumumab
Frerichs, Kristine A, Broekmans, Marloes E C, Marin Soto, Jhon A, van Kessel, Berris, Heymans, Martijn W, Holthof, Lisa C, Verkleij, Christie P M, Boominathan, Rengasamy, Vaidya, Bhavesh, Sendecki, Jocelyn, Axel, Amy, Gaudet, Francois, Pillarisetti, Kodandaram, Zweegman, Sonja, Adams, 3rd, Homer C, Mutis, Tuna, van de Donk, Niels W C J
Published in Clinical cancer research (01.05.2020)
Published in Clinical cancer research (01.05.2020)
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Journal Article
Towards effective immunotherapy of myeloma: enhanced elimination of myeloma cells by combination of lenalidomide with the human CD38 monoclonal antibody daratumumab
VAN DER VEER, Michael S, DE WEERS, Michel, VAN KESSEL, Berris, BAKKER, Joost M, WITTEBOL, Shulamiet, PARREN, Paul W. H. I, LOKHORST, Henk M, MUTIS, Tuna
Published in Haematologica (Roma) (01.02.2011)
Published in Haematologica (Roma) (01.02.2011)
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Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide
Nijhof, Inger S, Lammerts van Bueren, Jeroen J, van Kessel, Berris, Andre, Pascale, Morel, Yannis, Lokhorst, Henk M, van de Donk, Niels W C J, Parren, Paul W H I, Mutis, Tuna
Published in Haematologica (Roma) (01.02.2015)
Published in Haematologica (Roma) (01.02.2015)
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Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma
Groen, Richard W.J., Noort, Willy A., Raymakers, Reinier A., Prins, Henk-Jan, Aalders, Linda, Hofhuis, Frans M., Moerer, Petra, van Velzen, Jeroen F., Bloem, Andries C., van Kessel, Berris, Rozemuller, Henk, van Binsbergen, Ellen, Buijs, Arjan, Yuan, Huipin, de Bruijn, Joost D., de Weers, Michel, Parren, Paul W.H.I., Schuringa, Jan Jacob, Lokhorst, Henk M., Mutis, Tuna, Martens, Anton C.M.
Published in Blood (19.07.2012)
Published in Blood (19.07.2012)
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Gene-expression profiling of CD34+ cells from various hematopoietic stem-cell sources reveals functional differences in stem-cell activity
Ng, Yuk Yin, Kessel, Berris, Lokhorst, Henk M., Baert, Miranda R. M., Burg, Caroline M. M., Bloem, Andries C., Staal, Frank J. T.
Published in Journal of leukocyte biology (01.02.2004)
Published in Journal of leukocyte biology (01.02.2004)
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Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy
Eurelings, Marijke, Lokhorst, Henk M, Notermans, Nicolette C, Krijtenburg, Pieter Jaap, Kessel, Berris van, Eleveld, Mark J, Bloem, Andries, Wokke, John H, Poot, Martin, Buijs, Arjan
Published in Journal of the neurological sciences (15.09.2007)
Published in Journal of the neurological sciences (15.09.2007)
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Protein Geranylgeranylation Is Critical for the Regulation of Survival and Proliferation of Lymphoma Tumor Cells
VAN DE DONK, Niels W. C. J, SCHOTTE, Diana, KAMPHUIS, Marloes M. J, VAN MARION, Ariënne M. W, VAN KESSEL, Berris, BLOEM, Andries C, LOKHORST, Henk M
Published in Clinical cancer research (15.11.2003)
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Published in Clinical cancer research (15.11.2003)
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Abstract 4544: Multifaceted mechanism of action of DuoHexaBody-CD37 involves both complement- and Fc gamma receptor-mediated cytotoxicity in pre-clinical B-cell lymphoma models
Kil, Laurens P., Oostindie, Simone C., Strumane, Kristin, van der Horst, Hilma J., van Kessel, Berris, Overdijk, Marije B., Lingnau, Andreas, Brandhorst, Marcel, van den Brakel, Jeroen, Lindorfer, Margaret A., Taylor, Ronald P., Chamuleau, Martine E., Mutis, Tuna, Sasser, A. Kate, Schuurman, Janine, Parren, Paul W., Beurskens, Frank J., Breij, Esther C.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma
Nijhof, Inger S., Franssen, Laurens E., Levin, Mark-David, Bos, Gerard M.J., Broijl, Annemiek, Klein, Saskia K., Koene, Harry R., Bloem, Andries C., Beeker, Aart, Faber, Laura M., van der Spek, Ellen, Ypma, Paula F., Raymakers, Reinier, van Spronsen, Dick-Johan, Westerweel, Peter E., Oostvogels, Rimke, van Velzen, Jeroen, van Kessel, Berris, Mutis, Tuna, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M., van de Donk, Niels W.C.J.
Published in Blood (10.11.2016)
Published in Blood (10.11.2016)
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Hexabody-CD38, a Novel CD38 Antibody with a Hexamerization Enhancing Mutation, Demonstrates Enhanced Complement-Dependent Cytotoxicity and Shows Potent Anti-Tumor Activity in Preclinical Models of Hematological Malignancies
De Goeij, Bart ECG, Janmaat, Maarten L, Andringa, Grietje, Kil, Laurens, Van Kessel, Berris, Frerichs, Kristine A., Lingnau, Andreas, Freidig, Andreas, Mutis, Tuna, Sasser, A. Kate, Breij, Esther C.W., Van De Donk, Niels W. C.J., Ahmadi, Tahamtan, Satijn, David
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Abstract A12: Combination of the anti-CD38 monoclonal antibody daratumumab and all-trans retinoic acid
Nijhof, Inger S., Lokhorst, Henk M., Kessel, Berris van, Doshi, Parul, Sasser, Kate, Mutis, Tuna, Donk, Niels WCJ van de
Published in Clinical cancer research (01.09.2015)
Published in Clinical cancer research (01.09.2015)
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Selective in vitro expansion and efficient retroviral transduction of human CD34+ CD38– haematopoietic stem cells
Ng, Yuk Yin, Bloem, Andries C., Van Kessel, Berris, Lokhorst, Henk, Logtenberg, Ton, Staal, Frank J. T.
Published in British journal of haematology (01.04.2002)
Published in British journal of haematology (01.04.2002)
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Lenalidomide combined with low-dose cyclophosphamide and prednisone modulates Ikaros and Aiolos in lymphocytes, resulting in immunostimulatory effects in lenalidomide-refractory multiple myeloma patients
Franssen, Laurens E, Nijhof, Inger S, Bjorklund, Chad C, Chiu, Hsiling, Doorn, Ruud, van Velzen, Jeroen, Emmelot, Maarten, van Kessel, Berris, Levin, Mark-David, Bos, Gerard M J, Broijl, Annemiek, Klein, Saskia K, Koene, Harry R, Bloem, Andries C, Beeker, Aart, Faber, Laura M, van der Spek, Ellen, Raymakers, Reinier, Sonneveld, Pieter, Zweegman, Sonja, Lokhorst, Henk M, Thakurta, Anjan, Qian, Xiaozhong, Mutis, Tuna, van de Donk, Niels W C J
Published in Oncotarget (21.09.2018)
Published in Oncotarget (21.09.2018)
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