Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes
Bertrand, Denis, Shaw, Jim, Kalathiyappan, Manesh, Ng, Amanda Hui Qi, Kumar, M Senthil, Li, Chenhao, Dvornicic, Mirta, Soldo, Janja Paliska, Koh, Jia Yu, Tong, Chengxuan, Ng, Oon Tek, Barkham, Timothy, Young, Barnaby, Marimuthu, Kalisvar, Chng, Kern Rei, Sikic, Mile, Nagarajan, Niranjan
Published in Nature biotechnology (01.08.2019)
Published in Nature biotechnology (01.08.2019)
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Journal Article
Genomic characterization of three unique Dehalococcoides that respire on persistent polychlorinated biphenyls
Wang, Shanquan, Chng, Kern Rei, Wilm, Andreas, Zhao, Siyan, Yang, Kun-Lin, Nagarajan, Niranjan, He, Jianzhong
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2014)
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Journal Article
A transcriptional repressor co-regulatory network governing androgen response in prostate cancers
Chng, Kern Rei, Chang, Cheng Wei, Tan, Si Kee, Yang, Chong, Hong, Shu Zhen, Sng, Noel Yan Wei, Cheung, Edwin
Published in The EMBO journal (13.06.2012)
Published in The EMBO journal (13.06.2012)
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Journal Article
The liver–gut microbiota axis modulates hepatotoxicity of tacrine in the rat
Yip, Lian Yee, Aw, Chiu Cheong, Lee, Sze Han, Hong, Yi Shuen, Ku, Han Chen, Xu, Winston Hecheng, Chan, Jessalyn Mei Xuan, Cheong, Eleanor Jing Yi, Chng, Kern Rei, Ng, Amanda Hui Qi, Nagarajan, Niranjan, Mahendran, Ratha, Lee, Yuan Kun, Browne, Edward R., Chan, Eric Chun Yong
Published in Hepatology (Baltimore, Md.) (01.01.2018)
Published in Hepatology (Baltimore, Md.) (01.01.2018)
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Journal Article
Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut
Chng, Kern Rei, Ghosh, Tarini Shankar, Tan, Yi Han, Nandi, Tannistha, Lee, Ivor Russel, Ng, Amanda Hui Qi, Li, Chenhao, Ravikrishnan, Aarthi, Lim, Kar Mun, Lye, David, Barkham, Timothy, Raman, Karthik, Chen, Swaine L, Chai, Louis, Young, Barnaby, Gan, Yunn-Hwen, Nagarajan, Niranjan
Published in Nature ecology & evolution (01.09.2020)
Published in Nature ecology & evolution (01.09.2020)
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Journal Article
Atopic dermatitis microbiomes stratify into ecologic dermotypes enabling microbial virulence and disease severity
Tay, Angeline S.L., Li, Chenhao, Nandi, Tannistha, Chng, Kern Rei, Andiappan, Anand Kumar, Mettu, Vijaya Saradhi, de Cevins, Camille, Ravikrishnan, Aarthi, Dutertre, Charles-Antoine, Wong, X.F. Colin C., Ng, Amanda Hui Qi, Matta, Sri Anusha, Ginhoux, Florent, Rötzschke, Olaf, Chew, Fook Tim, Tang, Mark B.Y., Yew, Yik Weng, Nagarajan, Niranjan, Common, John E.A.
Published in Journal of allergy and clinical immunology (01.04.2021)
Published in Journal of allergy and clinical immunology (01.04.2021)
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Journal Article
Predicting microbial interactions through computational approaches
Li, Chenhao, Lim, Kun Ming Kenneth, Chng, Kern Rei, Nagarajan, Niranjan
Published in Methods (San Diego, Calif.) (01.06.2016)
Published in Methods (San Diego, Calif.) (01.06.2016)
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Journal Article
An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells
Zhang, Zhizhuo, Chng, Kern Rei, Lingadahalli, Shreyas, Chen, Zikai, Liu, Mei Hui, Do, Huy Hoang, Cai, Shaojiang, Rinaldi, Nicola, Poh, Huay Mei, Li, Guoliang, Sung, Ying Ying, Heng, Charlie L, Core, Leighton J, Tan, Si Kee, Ruan, Xiaoan, Lis, John T, Kellis, Manolis, Ruan, Yijun, Sung, Wing-Kin, Cheung, Edwin
Published in Genome research (01.02.2019)
Published in Genome research (01.02.2019)
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Journal Article
Gut metagenomes of Asian octogenarians reveal metabolic potential expansion and distinct microbial species associated with aging phenotypes
Ravikrishnan, Aarthi, Wijaya, Indrik, Png, Eileen, Chng, Kern Rei, Ho, Eliza Xin Pei, Ng, Amanda Hui Qi, Mohamed Naim, Ahmad Nazri, Gounot, Jean-Sebastien, Guan, Shou Ping, Hanqing, Jasinda Lee, Guan, Lihuan, Li, Chenhao, Koh, Jia Yu, de Sessions, Paola Florez, Koh, Woon-Puay, Feng, Lei, Ng, Tze Pin, Larbi, Anis, Maier, Andrea B, Kennedy, Brian K, Nagarajan, Niranjan
Published in Nature communications (05.09.2024)
Published in Nature communications (05.09.2024)
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Journal Article
Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances
Lim, Hui Kheng, Hughes, Christopher Owen, Lim, Michelle Jing Sin, Li, Jia’En Jasmine, Rakshit, Moumita, Yeo, Calvin, Chng, Kern Rei, Li, Angela, Chan, Joanne Sheot Harn, Ng, Kee Woei, Leavesley, David Ian, Smith, Benjamin Paul Chapman
Published in Archives of toxicology (01.05.2022)
Published in Archives of toxicology (01.05.2022)
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Journal Article
A metagenomics-based workflow for the detection and genomic characterization of GBS in raw freshwater fish
Sim, Kae Hwan, Ho, Jiaying, Lim, Jia Qi, Chan, Sheot Harn, Li, Angela, Chng, Kern Rei
Published in Microbiology spectrum (07.05.2024)
Published in Microbiology spectrum (07.05.2024)
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Journal Article
An expectation-maximization algorithm enables accurate ecological modeling using longitudinal microbiome sequencing data
Li, Chenhao, Chng, Kern Rei, Kwah, Junmei Samantha, Av-Shalom, Tamar V, Tucker-Kellogg, Lisa, Nagarajan, Niranjan
Published in Microbiome (22.08.2019)
Published in Microbiome (22.08.2019)
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Journal Article
Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma
Chng, Kern Rei, Chan, Sock Hoai, Ng, Amanda Hui Qi, Li, Chenhao, Jusakul, Apinya, Bertrand, Denis, Wilm, Andreas, Choo, Su Pin, Tan, Damien Meng Yew, Lim, Kiat Hon, Soetinko, Roy, Ong, Choon Kiat, Duda, Dan G., Dima, Simona, Popescu, Irinel, Wongkham, Chaisiri, Feng, Zhu, Yeoh, Khay Guan, Teh, Bin Tean, Yongvanit, Puangrat, Wongkham, Sopit, Bhudhisawasdi, Vajaraphongsa, Khuntikeo, Narong, Tan, Patrick, Pairojkul, Chawalit, Ngeow, Joanne, Nagarajan, Niranjan
Published in EBioMedicine (01.06.2016)
Published in EBioMedicine (01.06.2016)
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Journal Article
Long-term ecological and evolutionary dynamics in the gut microbiomes of carbapenemase-producing Enterobacteriaceae colonized subjects
Kang, Jonathan T. L., Teo, Jonathan J. Y., Bertrand, Denis, Ng, Amanda, Ravikrishnan, Aarthi, Yong, Melvin, Ng, Oon Tek, Marimuthu, Kalisvar, Chen, Swaine L., Chng, Kern Rei, Gan, Yunn-Hwen, Nagarajan, Niranjan
Published in Nature microbiology (01.10.2022)
Published in Nature microbiology (01.10.2022)
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Journal Article
Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare
Chng, Kern Rei, Tay, Angeline Su Ling, Li, Chenhao, Ng, Amanda Hui Qi, Wang, Jingjing, Suri, Bani Kaur, Matta, Sri Anusha, McGovern, Naomi, Janela, Baptiste, Wong, Xuan Fei Colin C., Sio, Yang Yie, Au, Bijin Veonice, Wilm, Andreas, De Sessions, Paola Florez, Lim, Thiam Chye, Tang, Mark Boon Yang, Ginhoux, Florent, Connolly, John E., Lane, E. Birgitte, Chew, Fook Tim, Common, John E. A., Nagarajan, Niranjan
Published in Nature microbiology (11.07.2016)
Published in Nature microbiology (11.07.2016)
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