A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ
Yakubovich, Daniel, Berlin, Shai, Kahanovitch, Uri, Rubinstein, Moran, Farhy-Tselnicker, Isabella, Styr, Boaz, Keren-Raifman, Tal, Dessauer, Carmen W, Dascal, Nathan
Published in PLoS computational biology (01.11.2015)
Published in PLoS computational biology (01.11.2015)
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Journal Article
Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner
Tabak, Galit, Keren-Raifman, Tal, Kahanovitch, Uri, Dascal, Nathan
Published in Scientific reports (24.01.2019)
Published in Scientific reports (24.01.2019)
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Journal Article
Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels
Reddy, Haritha P., Yakubovich, Daniel, Keren-Raifman, Tal, Tabak, Galit, Tsemakhovich, Vladimir A., Pedersen, Maria H., Shalomov, Boris, Colombo, Sophie, Goldstein, David B., Javitch, Jonathan A., Bera, Amal K., Dascal, Nathan
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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Journal Article
Molecular Mechanisms That Control Initiation and Termination of Physiological Depolarization-Evoked Transmitter Release
Kupchik, Yonatan M., Rashkovan, Grigory, Ohana, Lily, Keren-Raifman, Tal, Dascal, Nathan, Parnas, Hanna, Parnas, Itzchak
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2008)
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Journal Article
Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GαiGDP and Gβγ
Rubinstein, Moran, Peleg, Sagit, Berlin, Shai, Brass, Dovrat, Keren‐Raifman, Tal, Dessauer, Carmen W., Ivanina, Tatiana, Dascal, Nathan
Published in The Journal of physiology (01.07.2009)
Published in The Journal of physiology (01.07.2009)
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Journal Article
Modulation of distinct isoforms of L-type calcium channels by Gq-coupled receptors in Xenopus oocytes: Antagonistic effects of Gβγ and protein kinase C
Weiss, Sharon, Keren-Raifman, Tal, Oz, Shimrit, Ben-Mocha, Adva, Haase, Hannelore, Dascal, Nathan
Published in Channels (Austin, Tex.) (01.11.2012)
Published in Channels (Austin, Tex.) (01.11.2012)
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Journal Article
Phosphorylation of the Regulator of G Protein Signaling RGS9-1 by Protein Kinase A Is a Potential Mechanism of Light- and Ca2+-Mediated Regulation of G Protein Function in Photoreceptors
Balasubramanian, Nagaraj, Levay, Konstantin, Keren-Raifman, Tal, Faurobert, Eva, Slepak, Vladlen Z
Published in Biochemistry (Easton) (23.10.2001)
Published in Biochemistry (Easton) (23.10.2001)
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Journal Article
Ggamma Assists Gbeta to Activate GIRK1 by Relaxing Inhibitory Constraint
Tabak, Galit, Keren Raifman, Tal, Tsemakhovich, Vladimir, Dascal, Nathan
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats
Hausmann, Oliver N., Hu, Wen-Hui, Keren-Raifman, Tal, Witherow, D. Scott, Wang, Qiang, Levay, Konstantin, Frydel, Beata, Z. Slepak, Vladlen, R. Bethea, John
Published in The European journal of neuroscience (01.02.2002)
Published in The European journal of neuroscience (01.02.2002)
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Journal Article
Gβγ Activates GIRK2 with Low-Micromolar Affinity with Distinct Activation Pattern Compared to GIRK1/2
Yakubovich, Daniel, Kahanovitch, Uri, Tabak, Galit, Keren Raifman, Tal, Tsemakhovich, Vladimir, Ranjan Tripathy, Debi, Dessauer, Carmen W., Hirsch, Joel A., Dascal, Nathan
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Two Distinct Aspects of Coupling between Gαi Protein and G Protein-activated K+ Channel (GIRK) Revealed by Fluorescently Labeled Gαi3 Protein Subunits
Berlin, Shai, Tsemakhovich, Vladimir A., Castel, Ruth, Ivanina, Tatiana, Dessauer, Carmen W., Keren-Raifman, Tal, Dascal, Nathan
Published in The Journal of biological chemistry (23.09.2011)
Published in The Journal of biological chemistry (23.09.2011)
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Journal Article
Gαi and Gβγ Jointly Regulate the Conformations of a Gβγ Effector, the Neuronal G Protein-activated K+ Channel (GIRK)
Berlin, Shai, Keren-Raifman, Tal, Castel, Ruth, Rubinstein, Moran, Dessauer, Carmen W., Ivanina, Tatiana, Dascal, Nathan
Published in The Journal of biological chemistry (26.02.2010)
Published in The Journal of biological chemistry (26.02.2010)
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Journal Article
Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase
Treiber, Fritz, Rosker, Christian, Keren-Raifman, Tal, Steinecker, Bibiane, Gorischek, Astrid, Dascal, Nathan, Schreibmayer, Wolfgang
Published in Biochimica et biophysica acta (01.04.2013)
Published in Biochimica et biophysica acta (01.04.2013)
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Journal Article
A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of G[alpha] and G[Beta][gamma]: e1004598
Yakubovich, Daniel, Berlin, Shai, Kahanovitch, Uri, Rubinstein, Moran, Farhy-Tselnicker, Isabella, Styr, Boaz, Keren-Raifman, Tal, Dessauer, Carmen W, Dascal, Nathan
Published in PLoS computational biology (01.11.2015)
Published in PLoS computational biology (01.11.2015)
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Journal Article
The Human Muscarinic Receptor Couples to GαI3 Via Catalytic Collision
Berlin, Shai, Yakubovich, Daniel, Keren-Raifman, Tal, Dascal, Nathan
Published in Biophysical journal (01.01.2010)
Published in Biophysical journal (01.01.2010)
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Journal Article
Gαi1 and Gαi3 Differentially Interact with, and Regulate, the G Protein-activated K+ Channel
Ivanina, Tatiana, Varon, Dalia, Peleg, Sagit, Rishal, Ida, Porozov, Yuri, Dessauer, Carmen W., Keren-Raifman, Tal, Dascal, Nathan
Published in The Journal of biological chemistry (23.04.2004)
Published in The Journal of biological chemistry (23.04.2004)
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Journal Article
Modulation of distinct isoforms of L-type calcium channels by G q -coupled receptors in Xenopus oocytes: Antagonistic effects of Gβγ and protein kinase C
Weiss, Sharon, Keren-Raifman, Tal, Oz, Shimrit, Ben-Mocha, Adva, Haase, Hannelore, Dascal, Nathan
Published in Channels (Austin, Tex.) (18.11.2012)
Published in Channels (Austin, Tex.) (18.11.2012)
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Journal Article
Gαi and Gβγ Jointly Regulate the Conformations of a Gβγ Effector, the Neuronal G Protein-activated K+ Channel (GIRK)
Shai Berlin, Tal Keren-Raifman, Ruth Castel, Moran Rubinstein, Carmen W. Dessauer, Tatiana Ivanina, Nathan Dascal
Published in The Journal of biological chemistry (26.02.2010)
Published in The Journal of biological chemistry (26.02.2010)
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Journal Article