Preclinical safety and pharmacokinetic profile of 3K3A-APC, a novel, modified activated protein C for ischemic stroke
Williams, Patricia D, Zlokovic, Berislav V, Griffin, John H, Pryor, Kent E, Davis, Thomas P
Published in Current pharmaceutical design (01.09.2012)
Published in Current pharmaceutical design (01.09.2012)
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Journal Article
Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation
Lyden, Patrick D, Pryor, Kent E, Minigh, Jennifer, Davis, Thomas P, Griffin, John H, Levy, Howard, Zlokovic, Berislav V
Published in Frontiers in neurology (15.03.2021)
Published in Frontiers in neurology (15.03.2021)
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Journal Article
The activated core approach to combinatorial chemistry: A selection of new core molecules
Pryor, Kent E., Shipps, Gerald W., Skyler, David A., Rebek, Julius
Published in Tetrahedron (16.04.1998)
Published in Tetrahedron (16.04.1998)
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Journal Article
Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke
Lyden, Patrick, Pryor, Kent E., Coffey, Christopher S., Cudkowicz, Merit, Conwit, Robin, Jadhav, Ashutosh, Sawyer, Robert N., Claassen, Jan, Adeoye, Opeolu, Song, Shlee, Hannon, Peter, Rost, Natalia S., Hinduja, Archana, Torbey, Michel, Lee, Jin‐Moo, Benesch, Curtis, Rippee, Michael, Rymer, Marilyn, Froehler, Michael T., Clarke Haley, E., Johnson, Mark, Yankey, Jon, Magee, Kim, Qidwai, Julie, Levy, Howard, Mark Haacke, E., Fawaz, Miller, Davis, Thomas P., Toga, Arthur W., Griffin, John H., Zlokovic, Berislav V.
Published in Annals of neurology (01.01.2019)
Published in Annals of neurology (01.01.2019)
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Journal Article
Top Priorities for Cerebroprotective Studies-A Paradigm Shift: Report From STAIR XI
Lyden, Patrick, Buchan, Alastair, Boltze, Johannes, Fisher, Marc
Published in Stroke (1970) (01.09.2021)
Published in Stroke (1970) (01.09.2021)
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Journal Article
Randomized, controlled, dose escalation trial of a protease-activated receptor-1 agonist in acute ischemic stroke: Final Results of the RHAPSODY trial: A multi-center, Phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A-APC, a Recombinant Variant of Human Activated Protein C, in combination with tissue plasminogen activator, mechanical thrombectomy or both in moderate to severe acute ischemic stroke
Lyden, Patrick, Pryor, Kent E., Coffey, Christopher S., Cudkowicz, Merit, Conwit, Robin, Jadhav, Ashutosh, Sawyer, Robert N., Claassen, Jan, Adeoye, Opeolu, Song, Shlee, Hannon, Peter, Rost, Natalia S., Hinduja, Archana, Torbey, Michel, Lee, Jin-Moo, Benesch, Curtis, Rippee, Michael, Rymer, Marilyn, Froehler, Michael T., Haley, E. Clarke, Johnson, Mark, Yankey, Jon, Magee, Kim, Qidwai, Julie, Levy, Howard, Haacke, E. Mark, Fawaz, Miller, Davis, Thomas P., Toga, Arthur W., Griffin, John H., Zlokovic, Berislav V.
Published in Annals of neurology (01.01.2019)
Published in Annals of neurology (01.01.2019)
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Journal Article
A rapid method to identify exo-protease inhibitors
Pryor, Kent E., La Clair, James J.
Published in Bioorganic & medicinal chemistry letters (16.08.1999)
Published in Bioorganic & medicinal chemistry letters (16.08.1999)
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Journal Article
MODULATORS OF GSK-3 ACTIVITY
SEBO, LUBOMIR, KAHL, JEFFREY, JONES, BRYAN, PEI, YAZHONG, SULLIVAN, ROBERT, URBAN, JAN, LUM, CHRISTOPHER, PRYOR, KENT, E
Year of Publication 31.08.2006
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Year of Publication 31.08.2006
Patent
Plasminogen activator inhibitor antagonists
MADISON EDWIN L, PRYOR KENT E, BRUNCK TERENCE K, LIM-WILBY MARGUERITA, SEMPLE JOSEPH EDWARD
Year of Publication 28.10.2003
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Year of Publication 28.10.2003
Patent