3-Substituted Quinolines as RORγt Inverse Agonists
Tanis, Virginia M., Venkatesan, Hariharan, Cummings, Maxwell D., Albers, Michael, Kent Barbay, J., Herman, Krystal, Kummer, David A., Milligan, Cynthia, Nelen, Marina I., Nishimura, Rachel, Schlueter, Thomas, Scott, Brian, Spurlino, John, Wolin, Ronald, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
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Synthesis and characterization of 5,6,7,8-tetrahydroquinoline C5a receptor antagonists
Barbay, J. Kent, Gong, Yong, Buntinx, Mieke, Li, Jian, Claes, Concha, Hornby, Pamela J., Van Lommen, Guy, Van Wauwe, Jean, He, Wei
Published in Bioorganic & medicinal chemistry (15.04.2008)
Published in Bioorganic & medicinal chemistry (15.04.2008)
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Design and optimization of aniline-substituted tetrahydroquinoline C5a receptor antagonists
Gong, Yong, Barbay, J. Kent, Buntinx, Mieke, Li, Jian, Wauwe, Jean Van, Claes, Concha, Lommen, Guy Van, Hornby, Pamela J., He, Wei
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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6-Substituted quinolines as RORγt inverse agonists
Barbay, J. Kent, Cummings, Maxwell D., Abad, Marta, Castro, Glenda, Kreutter, Kevin D., Kummer, David A., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Tanis, Virginia M., Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Wolin, Ronald, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Journal Article
Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity
Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Synthesis and SAR of pyridazinone-substituted phenylalanine amide α4 integrin antagonists
YONG GONG, BARBAY, J. Kent, KIMBALL, Edward S, SANTULLI, Rosemary J, FISHER, M. Carolyn, DYATKIN, Alexey B, MISKOWSKI, Tamara A, HORNBY, Pamela J, WEI HE
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Substituted thieno[2,3-d]pyrimidines as adenosine A2A receptor antagonists
Shook, Brian C., Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Leonard, Kristi, Alford, Vernon, Powell, Mark T., Rassnick, Stefanie, Scannevin, Robert H., Carroll, Karen, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Lampron, Lisa, Westover, Lori, Rhodes, Kenneth, Jackson, Paul F.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease
Lu, Tianbao, Connolly, Peter J., Philippar, Ulrike, Sun, Weimei, Cummings, Maxwell D., Barbay, Kent, Gys, Luc, Van Nuffel, Luc, Austin, Nigel, Bekkers, Mariette, Shen, Fang, Cai, Ann, Attar, Ricardo, Meerpoel, Lieven, Edwards, James
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
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Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease
Shook, Brian C, Rassnick, Stefanie, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Powell, Mark T, Leonard, Kristi, Alford, Vernon, Scannevin, Robert H, Carroll, Karen, Lampron, Lisa, Westover, Lori, Lim, Heng-Keang, Russell, Ronald, Branum, Shawn, Wells, Kenneth M, Damon, Sandra, Youells, Scott, Li, Xun, Beauchamp, Derek A, Rhodes, Kenneth, Jackson, Paul F
Published in Journal of medicinal chemistry (09.02.2012)
Published in Journal of medicinal chemistry (09.02.2012)
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Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists
Shook, Brian C, Rassnick, Stefanie, Chakravarty, Devraj, Wallace, Nathaniel, Ault, Mark, Crooke, Jeffrey, Barbay, J Kent, Wang, Aihua, Leonard, Kristi, Powell, Mark T, Alford, Vernon, Hall, Daniel, Rupert, Kenneth C, Heintzelman, Geoffrey R, Hansen, Kristen, Bullington, James L, Scannevin, Robert H, Carroll, Karen, Lampron, Lisa, Westover, Lori, Russell, Ronald, Branum, Shawn, Wells, Kenneth, Damon, Sandra, Youells, Scott, Beauchamp, Derek, Li, Xun, Rhodes, Kenneth, Jackson, Paul F
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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POLYCYCLIC COMPOUNDS AS INHIBITORS OF BRUTON'S TYROSINE KINASE
CHEN WEI, BRAHMANANDA GHOSH, CHARLOTTE POOLEY DECKHUT, XIAO KUN, JAMES P EDWARDS, SCOTT D BEMBENEK, ZHANG FEIHUANG, NIDHI ARORA, JOSEPH KENT BARBAY, WEI JIANMEI, JENNIFER D VENABLE, CAI MIN, KEVIN D KREUTTER, ZHU YAOPING, WU YAO, GENESIS M BACANI, JOHN J M WIENER, LI GANG, MARK S TICHENOR
Year of Publication 13.05.2021
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Year of Publication 13.05.2021
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Synthesis and SAR of pyridazinone-substituted phenylalanine amide α 4 integrin antagonists
Gong, Yong, Kent Barbay, J., Kimball, Edward S., Santulli, Rosemary J., Carolyn Fisher, M., Dyatkin, Alexey B., Miskowski, Tamara A., Hornby, Pamela J., He, Wei
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
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Design and Characterization of Optimized Adenosine A(2A)/A(1) Receptor Antagonists for the Treatment of Parkinson's Disease
Shook, Brian C., Rassnick, Stefanie, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Powell, Mark T., Leonard, Kristi, Alford, Vernon, Scannevin, Robert H., Carroll, Karen, Lampron, Lisa, Westover, Lori, Lim, Heng-Keang, Russell, Ronald, Branum, Shawn, Wells, Kenneth M., Damon, Sandra, Youells, Scott, Li, Xun, Beauchamp, Derek A., Rhodes, Kenneth, Jackson, Paul F.
Published in Journal of medicinal chemistry (09.02.2012)
Published in Journal of medicinal chemistry (09.02.2012)
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Substituted thieno[2,3-d]pyrimidines as adenosine A(2A) receptor antagonists
Shook, Brian C., Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Leonard, Kristi, Alford, Vernon, Powell, Mark T., Rassnick, Stefanie, Scannevin, Robert H., Carroll, Karen, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Lampron, Lisa, Westover, Lori, Rhodes, Kenneth, Jackson, Paul F.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Design and Characterization of Optimized Adenosine A 2A /A 1 Receptor Antagonists for the Treatment of Parkinson's Disease
Shook, Brian C., Rassnick, Stefanie, Wallace, Nathaniel, Crooke, Jeffrey, Ault, Mark, Chakravarty, Devraj, Barbay, J. Kent, Wang, Aihua, Powell, Mark T., Leonard, Kristi, Alford, Vernon, Scannevin, Robert H., Carroll, Karen, Lampron, Lisa, Westover, Lori, Lim, Heng-Keang, Russell, Ronald, Branum, Shawn, Wells, Kenneth M., Damon, Sandra, Youells, Scott, Li, Xun, Beauchamp, Derek A., Rhodes, Kenneth, Jackson, Paul F.
Published in Journal of medicinal chemistry (09.02.2012)
Published in Journal of medicinal chemistry (09.02.2012)
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Inhibitors of KEAP1-Nrf2 protein-protein interaction
WEI, Jianmei, CHAI, Wenying, KUMMER, David A, VENABLE, Jennifer D, HIRST, Gavin C, MCCLURE, Kelly J, BARBAY, Kent J, NISHIMURA, Rachel T, KREUTTER, Kevin D, SHIH, Amy Y, VENKATESAN, Hariharan
Year of Publication 06.07.2023
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Year of Publication 06.07.2023
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Synthesis and SAR of pyridazinone-substituted phenylalanine amide alpha4 integrin antagonists
Gong, Yong, Kent Barbay, J, Kimball, Edward S, Santulli, Rosemary J, Carolyn Fisher, M, Dyatkin, Alexey B, Miskowski, Tamara A, Hornby, Pamela J, He, Wei
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Inhibitors of KEAP1-Nrf2 protein-protein interaction
WEI, Jianmei, CHAI, Wenying, KUMMER, David A, VENABLE, Jennifer D, HIRST, Gavin C, MCCLURE, Kelly J, BARBAY, Kent J, NISHIMURA, Rachel T, KREUTTER, Kevin D, SHIH, Amy Y, VENKATESAN, Hariharan
Year of Publication 21.04.2022
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Year of Publication 21.04.2022
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METHYLENE LINKED QUINOLINYL MODULATORS OF RORYT
MAUD URBANSKI, RONALD L. WOLIN, STEVEN GOLDBERG, UMAR MAHAROOF, JOAN PIERCE, XIAOHUA XUE, KENT BARBAY, HARIHARAN VENKATESAN, AIHUA WANG, JAMES P. EDWARDS, KEVIN D. KREUTTER, KRISTI A. LEONARD, RACHEL NISHIMURA, CRAIG R. WOODS, ANNE FOURIE, DAVID A. KUMMER
Year of Publication 16.02.2022
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Year of Publication 16.02.2022
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