The Influence of receptor kinetics on the onset and duration of action and the therapeutic index of NVA237 and tiotropium
Sykes, David A, Dowling, Mark R, Leighton-Davies, Juliet, Kent, Toby C, Fawcett, Lindsay, Renard, Emilie, Trifilieff, Alexandre, Charlton, Steven J
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2012)
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Journal Article
The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response
Roberts, Maxine J, Broome, Rebecca E, Kent, Toby C, Charlton, Steven J, Rosethorne, Elizabeth M
Published in Respiratory research (07.04.2018)
Published in Respiratory research (07.04.2018)
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Journal Article
The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35
MacKenzie, Amanda E, Caltabiano, Gianluigi, Kent, Toby C, Jenkins, Laura, McCallum, Jennifer E, Hudson, Brian D, Nicklin, Stuart A, Fawcett, Lindsay, Markwick, Rachel, Charlton, Steven J, Milligan, Graeme
Published in Molecular pharmacology (01.01.2014)
Published in Molecular pharmacology (01.01.2014)
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Journal Article
Evaluating the efficacy of upadacitinib in patients with moderate rheumatoid arthritis: a post-hoc analysis of the SELECT phase 3 trials
Conaghan, Philip G, Pavelka, Karel, Hsieh, Song-Chou, Bonnington, Terri-Leigh, Kent, Toby C, Marchbank, Katie, Edwards, Christopher J
Published in Rheumatology advances in practice (2023)
Published in Rheumatology advances in practice (2023)
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Journal Article
High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function
Bill, Anke, Rosethorne, Elizabeth M, Kent, Toby C, Fawcett, Lindsay, Burchell, Lynn, van Diepen, Michiel T, Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P, Renaud, Nicole A, Charlton, Steven J, Gosling, Martin, Gaither, L Alex, Groot-Kormelink, Paul J
Published in PloS one (02.06.2014)
Published in PloS one (02.06.2014)
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Journal Article
Impact of Ixekizumab Treatment on Itch and Psoriasis Area and Severity Index in Patients with Moderate-to-Severe Plaque Psoriasis: An Integrated Analysis of Two Phase III Randomized Studies
Yosipovitch, Gil, Reich, Adam, Steinhoff, Martin, Beselin, Anke, Kent, Toby, Dossenbach, Martin, Berggren, Lovisa, Henneges, Carsten, Luger, Thomas
Published in Dermatology and therapy (01.12.2018)
Published in Dermatology and therapy (01.12.2018)
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Journal Article
Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model
Trifilieff, Alexandre, Ethell, Brian T., Sykes, David A., Watson, Kenny J., Collingwood, Steve, Charlton, Steven J., Kent, Toby C.
Published in Toxicology and applied pharmacology (15.08.2015)
Published in Toxicology and applied pharmacology (15.08.2015)
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Journal Article
The Use of Cold Plasma Technology to Reduce Carryover in Screening Assays
Akhlaq, Mohammed, Rosethorne, Elizabeth M., Sattikar, Afrah, Kent, Toby C.
Published in Journal of Laboratory Automation (01.08.2013)
Published in Journal of Laboratory Automation (01.08.2013)
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Journal Article
Targeted literature review of current treatments and unmet need in moderate rheumatoid arthritis in the United Kingdom
Taylor, Peter C, Woods, Matthew, Rycroft, Catherine, Patel, Priya, Blanthorn-Hazell, Sophee, Kent, Toby, Bukhari, Marwan
Published in Rheumatology (Oxford, England) (03.11.2021)
Published in Rheumatology (Oxford, England) (03.11.2021)
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Journal Article
Upadacitinib response rates in patients with psoriatic arthritis enrolled in the SELECT-PsA-1 and SELECT-PsA-2 trials assessed according to modified PsARC
Coates, Laura C, Garrood, Toby, Gullick, Nicola, Helliwell, Philip, Kent, Toby, Marks, Jonathan, Tillett, William, Kaur-Papadakis, Daljit, Tahir, Hasan, van Haaren, Stijn, McInnes, Iain
Published in Rheumatology (Oxford, England) (23.12.2022)
Published in Rheumatology (Oxford, England) (23.12.2022)
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Journal Article
P127 Treating rheumatoid arthritis patients with moderate disease activity: an analysis of the upadacitinib SELECT Phase III randomised studies
Conaghan, Phillip G, Pavelka, Karel, Hsieh, Song-Chou, Bonnington, Terri-Leigh, Kent, Toby C, Edwards, Christopher J
Published in Rheumatology (Oxford, England) (25.04.2021)
Published in Rheumatology (Oxford, England) (25.04.2021)
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Journal Article
Development of a Generic Dual-Reporter Gene Assay for Screening G-Protein-Coupled Receptors
Kent, Toby C., Thompson, Kevin S.J., Naylor, Louise H.
Published in Journal of biomolecular screening (01.08.2005)
Published in Journal of biomolecular screening (01.08.2005)
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Journal Article
P174 Upadacitinib response rates in patients with psoriatic arthritis enrolled in the SELECT-PsA-1 and SELECT-PsA-2 trials assessed according to modified PsARC
Coates, Laura C, Garrood, Toby, Gullick, Nicola, Helliwell, Philip, Kent, Toby, Marks, Jonathan, Tillett, William, Kaur-Papadakis, Daljit, Tahir, Hasan, Haaren, Stijn van, McInnes, Iain
Published in Rheumatology (Oxford, England) (25.04.2021)
Published in Rheumatology (Oxford, England) (25.04.2021)
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Journal Article
Nothing about us without us: involving patient collaborators for machine learning applications in rheumatology
Shoop-Worrall, Stephanie J W, Cresswell, Katherine, Bolger, Imogen, Dillon, Beth, Hyrich, Kimme L, Geifman, Nophar, Ralph, Elizabeth, Dekaj, Fatjon, Jebson, Beth, Wanstall, Zoe, Kimonyo, Aline, Merali, Fatema, Sumner, Emma, Robinson, Emily, Dick, Prof Anew, Beresford, Prof Michael W., Carlsson, Emil, Fairlie, Joanna, Gritzfeld, Jenna F., Ramanan, Prof Athimalaipet, Duerr, Teresa, Barnes, Prof Michael, Ng, Sana, Thoon, Prof Wendy, Hyrich, Prof Kimme, Geifman, Nophar, Raychaudhuri, Prof Soumya, Morris, Prof Anew, Yarwood, Annie, Smith, Samantha, Tarasek, Damian, Shoop-Worrall, Stephanie, Lawson-Tovey, Saskia, Martin, Paul, Eyre, Prof Stephen, Wallace, Chris, Lin, Wei-Yu, Kent, Toby, Sornasse, Thierry, Jessica, Dr, Dews, Neisen; Sally-Anne, Diogo, Gil Reynolds, Ioannou, John, Al-Mossawi, Hussein, Neale, Helen
Published in Annals of the rheumatic diseases (01.12.2021)
Published in Annals of the rheumatic diseases (01.12.2021)
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Journal Article
The effect of ICER on screening methods involving CRE-mediated reporter gene expression
Kemp, Daniel M, George, Samantha E, Kent, Toby C, Bungay, Peter J, Naylor, Louise H
Published in Journal of biomolecular screening (01.04.2002)
Published in Journal of biomolecular screening (01.04.2002)
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Journal Article
245 Remission/low disease activity is an achievable treatment target in psoriatic arthritis (PsA): results from a routine care European cohort of PsA patients treated with ustekinumab or TNF inhibitors
Siebert, Stefan, Gossec, Laure, Bergmans, Paul, de Vlam, Kurt, Gremese, Elisa, Joven, Beatriz E, Korotaeva, Tatiana, Wright, Pamela B, Kent, Toby, Noel, Wim, Nurmohamed, Michael, Sfikakis, Petros, Smirnov, Pavel, Theander, Elke, Smolen, Josef
Published in Rheumatology (Oxford, England) (01.04.2019)
Published in Rheumatology (Oxford, England) (01.04.2019)
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