Opposing activities of IFITM proteins in SARS‐CoV‐2 infection
Shi, Guoli, Kenney, Adam D, Kudryashova, Elena, Zani, Ashley, Zhang, Lizhi, Lai, Kin Kui, Hall‐Stoodley, Luanne, Robinson, Richard T, Kudryashov, Dmitri S, Compton, Alex A, Yount, Jacob S
Published in The EMBO journal (01.02.2021)
Published in The EMBO journal (01.02.2021)
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Journal Article
From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections
Chemudupati, Mahesh, Kenney, Adam D., Bonifati, Serena, Zani, Ashley, McMichael, Temet M., Wu, Li, Yount, Jacob S.
Published in Biochimica et biophysica acta. Molecular cell research (01.03.2019)
Published in Biochimica et biophysica acta. Molecular cell research (01.03.2019)
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Journal Article
Interferon-induced transmembrane proteins inhibit cell fusion mediated by trophoblast syncytins
Zani, Ashley, Zhang, Lizhi, McMichael, Temet M., Kenney, Adam D., Chemudupati, Mahesh, Kwiek, Jesse J., Liu, Shan-Lu, Yount, Jacob S.
Published in The Journal of biological chemistry (27.12.2019)
Published in The Journal of biological chemistry (27.12.2019)
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Journal Article
Human Genetic Determinants of Viral Diseases
Kenney, Adam D, Dowdle, James A, Bozzacco, Leonia, McMichael, Temet M, St. Gelais, Corine, Panfil, Amanda R, Sun, Yan, Schlesinger, Larry S, Anderson, Matthew Z, Green, Patrick L, López, Carolina B, Rosenberg, Brad R, Wu, Li, Yount, Jacob S
Published in Annual review of genetics (27.11.2017)
Published in Annual review of genetics (27.11.2017)
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Journal Article
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
Shi, Guoli, Chiramel, Abhilash I, Li, Tiansheng, Lai, Kin Kui, Kenney, Adam D, Zani, Ashley, Eddy, Adrian C, Majdoul, Saliha, Zhang, Lizhi, Dempsey, Tirhas, Beare, Paul A, Kar, Swagata, Yewdell, Jonathan W, Best, Sonja M, Yount, Jacob S, Compton, Alex A
Published in The Journal of clinical investigation (15.12.2022)
Published in The Journal of clinical investigation (15.12.2022)
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Journal Article
MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
Sermersheim, Matthew, Kenney, Adam D., Lin, Pei-Hui, McMichael, Temet M., Cai, Chuanxi, Gumpper, Kristyn, Adesanya, T. M. Ayodele, Li, Haichang, Zhou, Xinyu, Park, Ki-Ho, Yount, Jacob S., Ma, Jianjie
Published in Nature communications (17.07.2020)
Published in Nature communications (17.07.2020)
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Journal Article
Innate immune control of influenza virus interspecies adaptation via IFITM3
Denz, Parker J., Speaks, Samuel, Kenney, Adam D., Eddy, Adrian C., Papa, Jonathan L., Roettger, Jack, Scace, Sydney C., Rubrum, Adam, Hemann, Emily A., Forero, Adriana, Webby, Richard J., Bowman, Andrew S., Yount, Jacob S.
Published in Nature communications (30.10.2024)
Published in Nature communications (30.10.2024)
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Journal Article
Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation
Speaks, Samuel, McFadden, Matthew I., Zani, Ashley, Solstad, Abigail, Leumi, Steve, Roettger, Jack E., Kenney, Adam D., Bone, Hannah, Zhang, Lizhi, Denz, Parker J., Eddy, Adrian C., Amer, Amal O., Robinson, Richard T., Cai, Chuanxi, Ma, Jianjie, Hemann, Emily A., Forero, Adriana, Yount, Jacob S.
Published in Nature communications (29.03.2024)
Published in Nature communications (29.03.2024)
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Journal Article
SARS-CoV-2 Nsp14 protein associates with IMPDH2 and activates NF-κB signaling
Li, Tai-Wei, Kenney, Adam D, Park, Jun-Gyu, Fiches, Guillaume N, Liu, Helu, Zhou, Dawei, Biswas, Ayan, Zhao, Weiqiang, Que, Jianwen, Santoso, Netty, Martinez-Sobrido, Luis, Yount, Jacob S, Zhu, Jian
Published in Frontiers in immunology (13.09.2022)
Published in Frontiers in immunology (13.09.2022)
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Journal Article
BEX1 is a critical determinant of viral myocarditis
Martens, Colton R, Dorn, Lisa E, Kenney, Adam D, Bansal, Shyam S, Yount, Jacob S, Accornero, Federica
Published in PLoS pathogens (01.02.2022)
Published in PLoS pathogens (01.02.2022)
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Journal Article
Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection
Laliotis, Georgios I, Kenney, Adam D, Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D, Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S, Tsichlis, Philip N
Published in Communications biology (11.10.2021)
Published in Communications biology (11.10.2021)
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Journal Article
Retraction Note: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection
Laliotis, Georgios I., Kenney, Adam D., Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D., Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S., Tsichlis, Philip N.
Published in Communications biology (15.12.2021)
Published in Communications biology (15.12.2021)
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Journal Article
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV‑2
Larue, Ross C, Xing, Enming, Kenney, Adam D, Zhang, Yuexiu, Tuazon, Jasmine A, Li, Jianrong, Yount, Jacob S, Li, Pui-Kai, Sharma, Amit
Published in Bioconjugate chemistry (20.01.2021)
Published in Bioconjugate chemistry (20.01.2021)
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Journal Article
IFITM3 requires an amphipathic helix for antiviral activity
Chesarino, Nicholas M, Compton, Alex A, McMichael, Temet M, Kenney, Adam D, Zhang, Lizhi, Soewarna, Victoria, Davis, Matthew, Schwartz, Olivier, Yount, Jacob S
Published in EMBO reports (01.10.2017)
Published in EMBO reports (01.10.2017)
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Journal Article
The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity
McMichael, Temet M., Zhang, Lizhi, Chemudupati, Mahesh, Hach, Jocelyn C., Kenney, Adam D., Hang, Howard C., Yount, Jacob S.
Published in The Journal of biological chemistry (29.12.2017)
Published in The Journal of biological chemistry (29.12.2017)
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Journal Article
The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection
Yang, Hua, Espada, Constanza E., Phillips, Stacia, Martinez, Nicholas, Kenney, Adam D., Yount, Jacob S., Xiong, Yong, Wu, Li
Published in The Journal of biological chemistry (01.06.2023)
Published in The Journal of biological chemistry (01.06.2023)
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Journal Article
Butyrate Reprograms Expression of Specific Interferon-Stimulated Genes
Chemudupati, Mahesh, Kenney, Adam D, Smith, Anna C, Fillinger, Robert J, Zhang, Lizhi, Zani, Ashley, Liu, Shan-Lu, Anderson, Matthew Z, Sharma, Amit, Yount, Jacob S
Published in Journal of virology (30.07.2020)
Published in Journal of virology (30.07.2020)
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Journal Article
IFITM3 protects the heart during influenza virus infection
Kenney, Adam D., McMichael, Temet M., Imas, Alexander, Chesarino, Nicholas M., Zhang, Lizhi, Dorn, Lisa E., Wu, Qian, Alfaour, Omar, Amari, Foued, Chen, Min, Zani, Ashley, Chemudupati, Mahesh, Accornero, Federica, Coppola, Vincenzo, Rajaram, Murugesan V. S., Yount, Jacob S.
Published in Proceedings of the National Academy of Sciences - PNAS (10.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (10.09.2019)
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Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2
Bednash, Joseph S, Johns, Finny, Farkas, Daniela, Elhance, Ajit, Adair, Jessica, Cress, Kirstin, Yount, Jacob S, Kenney, Adam D, Londino, James D, Mallampalli, Rama K
Published in American journal of respiratory cell and molecular biology (01.05.2023)
Published in American journal of respiratory cell and molecular biology (01.05.2023)
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Journal Article
Recombinant MG53 Protein Protects Mice from Lethal Influenza Virus Infection
Kenney, Adam D, Li, Zhongguang, Bian, Zehua, Zhou, Xinyu, Li, Haichang, Whitson, Bryan A, Tan, Tao, Cai, Chuanxi, Ma, Jianjie, Yount, Jacob S
Published in American journal of respiratory and critical care medicine (15.01.2021)
Published in American journal of respiratory and critical care medicine (15.01.2021)
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