Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8+ T Cell-Mediated Immunity in Colorectal Cancer
Bhattacharya, Nupur, Yuan, Robert, Prestwood, Tyler R., Penny, Hweixian Leong, DiMaio, Michael A., Reticker-Flynn, Nathan E., Krois, Charles R., Kenkel, Justin A., Pham, Tho D., Carmi, Yaron, Tolentino, Lorna, Choi, Okmi, Hulett, Reyna, Wang, Jinshan, Winer, Daniel A., Napoli, Joseph L., Engleman, Edgar G.
Published in Immunity (Cambridge, Mass.) (20.09.2016)
Published in Immunity (Cambridge, Mass.) (20.09.2016)
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
Reticker-Flynn, Nathan E., Zhang, Weiruo, Belk, Julia A., Basto, Pamela A., Escalante, Nichole K., Pilarowski, Genay O.W., Bejnood, Alborz, Martins, Maria M., Kenkel, Justin A., Linde, Ian L., Bagchi, Sreya, Yuan, Robert, Chang, Serena, Spitzer, Matthew H., Carmi, Yaron, Cheng, Jiahan, Tolentino, Lorna L., Choi, Okmi, Wu, Nancy, Kong, Christina S., Gentles, Andrew J., Sunwoo, John B., Satpathy, Ansuman T., Plevritis, Sylvia K., Engleman, Edgar G.
Published in Cell (26.05.2022)
Published in Cell (26.05.2022)
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Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions
Filatenkov, Alexander, Baker, Jeanette, Mueller, Antonia M S, Kenkel, Justin, Ahn, G-One, Dutt, Suparna, Zhang, Nigel, Kohrt, Holbrook, Jensen, Kent, Dejbakhsh-Jones, Sussan, Shizuru, Judith A, Negrin, Robert N, Engleman, Edgar G, Strober, Samuel
Published in Clinical cancer research (15.08.2015)
Published in Clinical cancer research (15.08.2015)
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Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity
Carmi, Yaron, Spitzer, Matthew H., Linde, Ian L., Burt, Bryan M., Prestwood, Tyler R., Perlman, Nicola, Davidson, Matthew G., Kenkel, Justin A., Segal, Ehud, Pusapati, Ganesh V., Bhattacharya, Nupur, Engleman, Edgar G.
Published in Nature (London) (07.05.2015)
Published in Nature (London) (07.05.2015)
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B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
Winer, Daniel A, Winer, Shawn, Shen, Lei, Wadia, Persis P, Yantha, Jason, Paltser, Geoffrey, Tsui, Hubert, Wu, Ping, Davidson, Matthew G, Alonso, Michael N, Leong, Hwei X, Glassford, Alec, Caimol, Maria, Kenkel, Justin A, Tedder, Thomas F, McLaughlin, Tracey, Miklos, David B, Dosch, H-Michael, Engleman, Edgar G
Published in Nature medicine (01.05.2011)
Published in Nature medicine (01.05.2011)
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An Immunosuppressive Dendritic Cell Subset Accumulates at Secondary Sites and Promotes Metastasis in Pancreatic Cancer
Kenkel, Justin A, Tseng, William W, Davidson, Matthew G, Tolentino, Lorna L, Choi, Okmi, Bhattacharya, Nupur, Seeley, E Scott, Winer, Daniel A, Reticker-Flynn, Nathan E, Engleman, Edgar G
Published in Cancer research (Chicago, Ill.) (01.08.2017)
Published in Cancer research (Chicago, Ill.) (01.08.2017)
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A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence
Mamedov, Murad R., Scholzen, Anja, Nair, Ramesh V., Cumnock, Katherine, Kenkel, Justin A., Oliveira, Jose Henrique M., Trujillo, Damian L., Saligrama, Naresha, Zhang, Yue, Rubelt, Florian, Schneider, David S., Chien, Yueh-hsiu, Sauerwein, Robert W., Davis, Mark M.
Published in Immunity (Cambridge, Mass.) (20.02.2018)
Published in Immunity (Cambridge, Mass.) (20.02.2018)
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N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
Zhou, Matthew N., Delaveris, Corleone S., Kramer, Jessica R., Kenkel, Justin A., Engleman, Edgar G., Bertozzi, Carolyn R.
Published in Angewandte Chemie International Edition (12.03.2018)
Published in Angewandte Chemie International Edition (12.03.2018)
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Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma
Penny, Hweixian Leong, Sieow, Je Lin, Gun, Sin Yee, Lau, Mai Chan, Lee, Bernett, Tan, Jasmine, Phua, Cindy, Toh, Florida, Nga, Yvonne, Yeap, Wei Hseun, Janela, Baptiste, Kumar, Dilip, Chen, Hao, Yeong, Joe, Kenkel, Justin A, Pang, Angela, Lim, Diana, Toh, Han Chong, Hon, Tony Lim Kiat, Johnson, Christopher I, Khameneh, Hanif Javanmard, Mortellaro, Alessandra, Engleman, Edgar G, Rotzschke, Olaf, Ginhoux, Florent, Abastado, Jean-Pierre, Chen, Jinmiao, Wong, Siew Cheng
Published in International journal of molecular sciences (14.06.2021)
Published in International journal of molecular sciences (14.06.2021)
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Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer
Yuan, Robert, Bhattacharya, Nupur, Kenkel, Justin A, Shen, Jeanne, DiMaio, Michael A, Bagchi, Sreya, Prestwood, Tyler R, Habtezion, Aida, Engleman, Edgar G
Published in Frontiers in oncology (13.11.2020)
Published in Frontiers in oncology (13.11.2020)
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Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity
Ackerman, Shelley E, Pearson, Cecelia I, Gregorio, Joshua D, Gonzalez, Joseph C, Kenkel, Justin A, Hartmann, Felix J, Luo, Angela, Ho, Po Y, LeBlanc, Heidi, Blum, Lisa K, Kimmey, Samuel C, Luo, Andrew, Nguyen, Murray L, Paik, Jason C, Sheu, Lauren Y, Ackerman, Benjamin, Lee, Arthur, Li, Hai, Melrose, Jennifer, Laura, Richard P, Ramani, Vishnu C, Henning, Karla A, Jackson, David Y, Safina, Brian S, Yonehiro, Grant, Devens, Bruce H, Carmi, Yaron, Chapin, Steven J, Bendall, Sean C, Kowanetz, Marcin, Dornan, David, Engleman, Edgar G, Alonso, Michael N
Published in Nature cancer (01.01.2021)
Published in Nature cancer (01.01.2021)
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Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance
Revelo, Xavier S., Ghazarian, Magar, Chng, Melissa Hui Yen, Luck, Helen, Kim, Justin H., Zeng, Kejing, Shi, Sally Y., Tsai, Sue, Lei, Helena, Kenkel, Justin, Liu, Chih Long, Tangsombatvisit, Stephanie, Tsui, Hubert, Sima, Corneliu, Xiao, Changting, Shen, Lei, Li, Xiaoying, Jin, Tianru, Lewis, Gary F., Woo, Minna, Utz, Paul J., Glogauer, Michael, Engleman, Edgar, Winer, Shawn, Winer, Daniel A.
Published in Cell reports (Cambridge) (19.07.2016)
Published in Cell reports (Cambridge) (19.07.2016)
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Development of an Orthotopic Model of Invasive Pancreatic Cancer in an Immunocompetent Murine Host
TSENG, William W, WINER, Daniel, KENKEL, Justin A, CHOI, Okmi, SHAIN, Alan H, POLLACK, Jonathan R, FRENCH, Randy, LOWY, Andrew M, ENGLEMAN, Edgar G
Published in Clinical cancer research (15.07.2010)
Published in Clinical cancer research (15.07.2010)
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Th17 cells induce Th1-polarizing monocyte-derived dendritic cells
Davidson, Matthew G, Alonso, Michael N, Yuan, Robert, Axtell, Robert C, Kenkel, Justin A, Suhoski, Megan M, González, Joseph C, Steinman, Lawrence, Engleman, Edgar G
Published in The Journal of immunology (1950) (01.08.2013)
Published in The Journal of immunology (1950) (01.08.2013)
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In vivo T cell activation induces the formation of CD209(+) PDL-2(+) dendritic cells
Davidson, Matthew G, Alonso, Michael N, Kenkel, Justin A, Suhoski, Megan M, González, Joseph C, Yuan, Robert, Engleman, Edgar G
Published in PloS one (02.10.2013)
Published in PloS one (02.10.2013)
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720 A phase 1/2 study of BDC-3042, a novel Dectin-2 agonistic antibody, in patients with advanced cancers
Giordano, Antonio, Dumbrava, Ecaterina, Parikh, Aparna R, Kenkel, Justin, Cai, Danlin, Demady, Damon, Xu, Lu, Alonso, Michael N, Ackerman, Shelley E, Perez, Edith A, Wilks, Sharon
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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605 Systemically administered HER2-targeted ISACs provoke a rapid, local response that engages the innate and adaptive arms of the immune system to eradicate tumors in preclinical models
LeBlanc, Heidi, Pearson, Cecelia, Kenkel, Justin, Blum, LIsa, Ho, Po, Luo, Angela, Laura, Richard, Zhou, Matthew, Gregorio, Joshua, Luo, Andrew, Ackerman, Shelley, Safina, Brian, Dornan, David, Alonso, Michael, Kowanetz, Marcin
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
Zhou, Matthew N., Delaveris, Corleone S., Kramer, Jessica R., Kenkel, Justin A., Engleman, Edgar G., Bertozzi, Carolyn R.
Published in Angewandte Chemie (12.03.2018)
Published in Angewandte Chemie (12.03.2018)
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Journal Article
Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice
Penny, Hweixian Leong, Prestwood, Tyler R, Bhattacharya, Nupur, Sun, Fionna, Kenkel, Justin A, Davidson, Matthew G, Shen, Lei, Zuniga, Luis A, Seeley, E Scott, Pai, Reetesh, Choi, Okmi, Tolentino, Lorna, Wang, Jinshan, Napoli, Joseph L, Engleman, Edgar G
Published in Cancer immunology research (01.11.2016)
Published in Cancer immunology research (01.11.2016)
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A phase 1/2 study of BDC-3042, a novel dectin-2 agonistic antibody, in patients with advanced cancers
Salkeni, Mohamad Adham, Vandross, Andrae L., Dumbrava, Ecaterina Elena, Giordano, Antonio, Chen, Christopher, Kenkel, Justin, Cai, Danlin, Xu, Lu, Alonso, Michael N., Ackerman, Shelley, Yu, Tai, Colburn, Dawn E., Perez, Edith A., Wilks, Sharon
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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