Cardiac differentiation of human pluripotent stem cells in scalable suspension culture
Kempf, Henning, Kropp, Christina, Olmer, Ruth, Martin, Ulrich, Zweigerdt, Robert
Published in Nature protocols (01.09.2015)
Published in Nature protocols (01.09.2015)
Get full text
Journal Article
Large-scale production of human pluripotent stem cell derived cardiomyocytes
Kempf, Henning, Andree, Birgit, Zweigerdt, Robert
Published in Advanced drug delivery reviews (15.01.2016)
Published in Advanced drug delivery reviews (15.01.2016)
Get full text
Journal Article
Human heart-forming organoids recapitulate early heart and foregut development
Drakhlis, Lika, Biswanath, Santoshi, Farr, Clara-Milena, Lupanow, Victoria, Teske, Jana, Ritzenhoff, Katharina, Franke, Annika, Manstein, Felix, Bolesani, Emiliano, Kempf, Henning, Liebscher, Simone, Schenke-Layland, Katja, Hegermann, Jan, Nolte, Lena, Meyer, Heiko, de la Roche, Jeanne, Thiemann, Stefan, Wahl-Schott, Christian, Martin, Ulrich, Zweigerdt, Robert
Published in Nature biotechnology (01.06.2021)
Published in Nature biotechnology (01.06.2021)
Get full text
Journal Article
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections
Ackermann, Mania, Kempf, Henning, Hetzel, Miriam, Hesse, Christina, Hashtchin, Anna Rafiei, Brinkert, Kerstin, Schott, Juliane Wilhelmine, Haake, Kathrin, Kühnel, Mark Philipp, Glage, Silke, Figueiredo, Constanca, Jonigk, Danny, Sewald, Katherina, Schambach, Axel, Wronski, Sabine, Moritz, Thomas, Martin, Ulrich, Zweigerdt, Robert, Munder, Antje, Lachmann, Nico
Published in Nature communications (30.11.2018)
Published in Nature communications (30.11.2018)
Get full text
Journal Article
Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors
Ackermann, Mania, Rafiei Hashtchin, Anna, Manstein, Felix, Carvalho Oliveira, Marco, Kempf, Henning, Zweigerdt, Robert, Lachmann, Nico
Published in Nature protocols (01.02.2022)
Published in Nature protocols (01.02.2022)
Get full text
Journal Article
Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single‐Use Stirred Tank Bioreactors
Kropp, Christina, Kempf, Henning, Halloin, Caroline, Robles-Diaz, Diana, Franke, Annika, Scheper, Thomas, Kinast, Katharina, Knorpp, Thomas, Joos, Thomas O., Haverich, Axel, Martin, Ulrich, Zweigerdt, Robert, Olmer, Ruth
Published in Stem cells translational medicine (01.10.2016)
Published in Stem cells translational medicine (01.10.2016)
Get full text
Journal Article
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
Kempf, Henning, Olmer, Ruth, Haase, Alexandra, Franke, Annika, Bolesani, Emiliano, Schwanke, Kristin, Robles-Diaz, Diana, Coffee, Michelle, Göhring, Gudrun, Dräger, Gerald, Pötz, Oliver, Joos, Thomas, Martinez-Hackert, Erik, Haverich, Axel, Buettner, Falk F. R., Martin, Ulrich, Zweigerdt, Robert
Published in Nature communications (09.12.2016)
Published in Nature communications (09.12.2016)
Get full text
Journal Article
The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells
Dahlmann, Julia, Kensah, George, Kempf, Henning, Skvorc, David, Gawol, Anke, Elliott, David A, Dräger, Gerald, Zweigerdt, Robert, Martin, Ulrich, Gruh, Ina
Published in Biomaterials (01.03.2013)
Published in Biomaterials (01.03.2013)
Get full text
Journal Article
Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels
de la Roche, Jeanne, Angsutararux, Paweorn, Kempf, Henning, Janan, Montira, Bolesani, Emiliano, Thiemann, Stefan, Wojciechowski, Daniel, Coffee, Michelle, Franke, Annika, Schwanke, Kristin, Leffler, Andreas, Luanpitpong, Sudjit, Issaragrisil, Surapol, Fischer, Martin, Zweigerdt, Robert
Published in Scientific reports (01.08.2019)
Published in Scientific reports (01.08.2019)
Get full text
Journal Article
Differentiation of Human Pluripotent Stem Cells into Functional Endothelial Cells in Scalable Suspension Culture
Olmer, Ruth, Engels, Lena, Usman, Abdulai, Menke, Sandra, Malik, Muhammad Nasir Hayat, Pessler, Frank, Göhring, Gudrun, Bornhorst, Dorothee, Bolten, Svenja, Abdelilah-Seyfried, Salim, Scheper, Thomas, Kempf, Henning, Zweigerdt, Robert, Martin, Ulrich
Published in Stem cell reports (08.05.2018)
Published in Stem cell reports (08.05.2018)
Get full text
Journal Article
Controlling Expansion and Cardiomyogenic Differentiation of Human Pluripotent Stem Cells in Scalable Suspension Culture
Kempf, Henning, Olmer, Ruth, Kropp, Christina, Rückert, Michael, Jara-Avaca, Monica, Robles-Diaz, Diana, Franke, Annika, Elliott, David A., Wojciechowski, Daniel, Fischer, Martin, Roa Lara, Angelica, Kensah, George, Gruh, Ina, Haverich, Axel, Martin, Ulrich, Zweigerdt, Robert
Published in Stem cell reports (09.12.2014)
Published in Stem cell reports (09.12.2014)
Get full text
Journal Article
A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification
Ackermann, Mania, Haake, Kathrin, Kempf, Henning, Kaschutnig, Paul, Weiss, Anna-Carina, Nguyen, Ariane H H, Abeln, Markus, Merkert, Sylvia, Kühnel, Mark Phillip, Hartmann, Dorothee, Jonigk, Danny, Thum, Thomas, Kispert, Andreas, Milsom, Michael D, Lachmann, Nico
Published in Haematologica (Roma) (01.05.2021)
Published in Haematologica (Roma) (01.05.2021)
Get full text
Journal Article
Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis
Jaeger, Benedikt, Schupp, Jonas Christian, Plappert, Linda, Terwolbeck, Oliver, Artysh, Nataliia, Kayser, Gian, Engelhard, Peggy, Adams, Taylor Sterling, Zweigerdt, Robert, Kempf, Henning, Lienenklaus, Stefan, Garrels, Wiebke, Nazarenko, Irina, Jonigk, Danny, Wygrecka, Malgorzata, Klatt, Denise, Schambach, Axel, Kaminski, Naftali, Prasse, Antje
Published in Nature communications (26.09.2022)
Published in Nature communications (26.09.2022)
Get full text
Journal Article
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
Halloin, Caroline, Schwanke, Kristin, Löbel, Wiebke, Franke, Annika, Szepes, Monika, Biswanath, Santoshi, Wunderlich, Stephanie, Merkert, Sylvia, Weber, Natalie, Osten, Felix, de la Roche, Jeanne, Polten, Felix, Christoph Wollert, Kai, Kraft, Theresia, Fischer, Martin, Martin, Ulrich, Gruh, Ina, Kempf, Henning, Zweigerdt, Robert
Published in Stem cell reports (13.08.2019)
Published in Stem cell reports (13.08.2019)
Get full text
Journal Article
Expansion of functional personalized cells with specific transgene combinations
Lipps, Christoph, Klein, Franziska, Wahlicht, Tom, Seiffert, Virginia, Butueva, Milada, Zauers, Jeannette, Truschel, Theresa, Luckner, Martin, Köster, Mario, MacLeod, Roderick, Pezoldt, Jörn, Hühn, Jochen, Yuan, Qinggong, Müller, Peter Paul, Kempf, Henning, Zweigerdt, Robert, Dittrich-Breiholz, Oliver, Pufe, Thomas, Beckmann, Rainer, Drescher, Wolf, Riancho, Jose, Sañudo, Carolina, Korff, Thomas, Opalka, Bertram, Rebmann, Vera, Göthert, Joachim R., Alves, Paula M., Ott, Michael, Schucht, Roland, Hauser, Hansjörg, Wirth, Dagmar, May, Tobias
Published in Nature communications (08.03.2018)
Published in Nature communications (08.03.2018)
Get full text
Journal Article
Publisher Correction: Human heart-forming organoids recapitulate early heart and foregut development
Drakhlis, Lika, Biswanath, Santoshi, Farr, Clara-Milena, Lupanow, Victoria, Teske, Jana, Ritzenhoff, Katharina, Franke, Annika, Manstein, Felix, Bolesani, Emiliano, Kempf, Henning, Liebscher, Simone, Schenke-Layland, Katja, Hegermann, Jan, Nolte, Lena, Meyer, Heiko, de la Roche, Jeanne, Thiemann, Stefan, Wahl-Schott, Christian, Martin, Ulrich, Zweigerdt, Robert
Published in Nature biotechnology (01.06.2021)
Published in Nature biotechnology (01.06.2021)
Get full text
Journal Article
Paracrine mechanisms in early differentiation of human pluripotent stem cells: Insights from a mathematical model
Gaspari, Erika, Franke, Annika, Robles-Diaz, Diana, Zweigerdt, Robert, Roeder, Ingo, Zerjatke, Thomas, Kempf, Henning
Published in Stem cell research (01.10.2018)
Published in Stem cell research (01.10.2018)
Get full text
Journal Article
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice
Mucci, Adele, Lopez-Rodriguez, Elena, Hetzel, Miriam, Liu, Serena, Suzuki, Takuji, Happle, Christine, Ackermann, Mania, Kempf, Henning, Hillje, Roman, Kunkiel, Jessica, Janosz, Ewa, Brennig, Sebastian, Glage, Silke, Bankstahl, Jens P., Dettmer, Sabine, Rodt, Thomas, Gohring, Gudrun, Trapnell, Bruce, Hansen, Gesine, Trapnell, Cole, Knudsen, Lars, Lachmann, Nico, Moritz, Thomas
Published in Stem cell reports (11.09.2018)
Published in Stem cell reports (11.09.2018)
Get full text
Journal Article
Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: considerations on process development
Massai, Diana, Bolesani, Emiliano, Diaz, Diana Robles, Kropp, Christina, Kempf, Henning, Halloin, Caroline, Martin, Ulrich, Braniste, Tudor, Isu, Giuseppe, Harms, Vanessa, Morbiducci, Umberto, Dräger, Gerald, Zweigerdt, Robert
Published in Scientific reports (21.06.2017)
Published in Scientific reports (21.06.2017)
Get full text
Journal Article
A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device
Christoffersson, Jonas, Meier, Florian, Kempf, Henning, Schwanke, Kristin, Coffee, Michelle, Beilmann, Mario, Zweigerdt, Robert, Mandenius, Carl-Fredrik
Published in Bioengineering (Basel) (04.05.2018)
Published in Bioengineering (Basel) (04.05.2018)
Get full text
Journal Article