Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen
Published in Nature medicine (01.06.2019)
Published in Nature medicine (01.06.2019)
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Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial
van Ramshorst, Mette S, van der Voort, Anna, van Werkhoven, Erik D, Mandjes, Ingrid A, Kemper, Inge, Dezentjé, Vincent O, Oving, Irma M, Honkoop, Aafke H, Tick, Lidwine W, van de Wouw, Agnes J, Mandigers, Caroline M, van Warmerdam, Laurence J, Wesseling, Jelle, Vrancken Peeters, Marie-Jeanne T, Linn, Sabine C, Sonke, Gabe S
Published in The lancet oncology (01.12.2018)
Published in The lancet oncology (01.12.2018)
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Three-Year Follow-up of Neoadjuvant Chemotherapy With or Without Anthracyclines in the Presence of Dual ERBB2 Blockade in Patients With ERBB2-Positive Breast Cancer: A Secondary Analysis of the TRAIN-2 Randomized, Phase 3 Trial
van der Voort, Anna, van Ramshorst, Mette S, van Werkhoven, Erik D, Mandjes, Ingrid A, Kemper, Inge, Vulink, Annelie J, Oving, Irma M, Honkoop, Aafke H, Tick, Lidwine W, van de Wouw, Agnes J, Mandigers, Caroline M, van Warmerdam, Laurence J, Wesseling, Jelle, Vrancken Peeters, Marie-Jeanne T, Linn, Sabine C, Sonke, Gabe S
Published in JAMA oncology (01.07.2021)
Published in JAMA oncology (01.07.2021)
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MRI-guided optimisation of neoadjuvant chemotherapy duration in stage II–III HER2-positive breast cancer (TRAIN-3): a multicentre, single-arm, phase 2 study
van der Voort, Anna, Louis, Fleur M, van Ramshorst, Mette S, Kessels, Rob, Mandjes, Ingrid A, Kemper, Inge, Agterof, Mariette J, van der Steeg, Wim A, Heijns, Joan B, van Bekkum, Marlies L, Siemerink, Ester J, Kuijer, Philomeen M, Scholten, Astrid, Wesseling, Jelle, Vrancken Peeters, Marie-Jeanne T F D, Mann, Ritse M, Sonke, Gabe S, van Leeuwen-Stok, E., van Leeuwen, L., de Graaf, H., van Riel, J.M.G.H., Houtsma, D., Vrijaldenhoven, S., van der Velden, A.W.G., Peerdeman, A.L., van den Brink - Schimmel, R.J., Drooger, J.C., Imholz, A.L.Th, Dercksen, M.W., Oulad Hadj, J., Bakker, S.D., van der Wouw, A.J., Kerver, E.D., Bouma, G., van Schaik, C., de Boer, M., Mandigers, C.M.P.W., Koornstra, R.H.T., Smals, A., Rietbroek, R.C., van der Padt - Pruijsten, A., den Boer, M.O., Bos, H., Schiphorst, P.P.J.B.M., Vriens, B.E.P.J., van Rossum, Q.C., Tol, J., Hoogwerf - Kluft, D., Kruijtzer - Schimmel, C.M.F., Oosterkamp, H.M., Baas, I.O., Dietvorst, A.H.P., Davidis - van Schoonhoven, M., van Dijk, M.A.
Published in The lancet oncology (01.05.2024)
Published in The lancet oncology (01.05.2024)
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Three-year follow-up of neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2-blockade for HER2-positive breast cancer (TRAIN-2): A randomized phase III trial
van der Voort, Anna, van Ramshorst, Mette S., van Werkhoven, Erik D., Mandjes, Ingrid A., Kemper, Inge, Vulink, Annelie J., Oving, Irma M., Honkoop, Aafke H., Tick, Lidwine W., van de Wouw, Agnes J., Mandigers, Caroline M., van Warmerdam, Laurence J. C., Wesseling, Jelle, Vrancken Peeters, Marie-Jeanne T.F.D, Linn, Sabine C., Sonke, Gabe S.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study
van Ramshorst, Mette S, van Werkhoven, Erik, Honkoop, Aafke H, Dezentjé, Vincent O, Oving, Irma M, Mandjes, Ingrid A, Kemper, Inge, Smorenburg, Carolien H, Stouthard, Jacqueline M, Linn, Sabine C, Sonke, Gabe S
Published in Breast (Edinburgh) (01.10.2016)
Published in Breast (Edinburgh) (01.10.2016)
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Adaptive phase II randomized trial of nivolumab after induction treatment in triple negative breast cancer (TONIC trial): Final response data stage I and first translational data
Kok, Marleen, Voorwerk, Leonie, Horlings, Hugo, Sikorska, Karolina, van der Vijver, Koen, Slagter, Maarten, Warren, Sarah, Ong, SuFey, Wiersma, Terry, Russell, Nicola, Lalezari, Ferry, de Maaker, Michiel, Kemper, Inge, Mandjes, Ingrid A., Chalabi, Myriam, Sonke, Gabe S., Salgado, Roberto, Linn, Sabine C., Schumacher, Ton, Blank, Christian U.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Abstract P3-06-01: Unleashing NK- and CD8 T cells by combining monalizumab (anti-NKG2A) and trastuzumab for metastatic HER2+ breast cancer: first results MIMOSA trial
Geurts, Veerle, Voorwerk, Leonie, Sikorska, Karolina, Salgado, Roberto, van de Vijver, Koen, van Dongen, Marloes, Kemper, Inge, Mandjes, Ingrid A., Heuver-mes, Martine, Haanen, John, Sonke, Gabe S., Horlings, Hugo, Kok, Marleen
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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A phase III trial of neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2-blockade for HER2+ breast cancer: The TRAIN-2 study (BOOG 2012-03)
Van Ramshorst, Mette S., van Werkhoven, Erik, Mandjes, Ingrid A., Kemper, Inge, Dezentjé, Vincent O., Oving, Irma M., Honkoop, Aafke H., Tick, Lidwine W, Van de Wouw, Agnes W, Mandigers, Caroline M, Wesseling, Jelle, Vrancken Peeters, Marie-Jeanne, Linn, Sabine C., Sonke, Gabe S.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Abstract PD18-06: Image-guided optimization of neoadjuvant chemotherapy duration in stage II and III HER2-positive breast cancer: radiologic and pathologic complete response (pCR) rates in the multicenter phase 2 TRAIN-3 study (BOOG 2018-01)
van der Voort, Anna, van Ramshorst, Mette S., Kessels, Rob, Mandjes, Ingrid A., Kemper, Inge, Agterof, Mariëtte J., van der Steeg, Wim A., Heijns, Joan B., van Bekkum, Marlies L., Siemerink, Ester J., Kuijer, Philomeen M., Scholten, Astrid, Wesseling, Jelle, Peeters, Marie-Jeanne T.F.D. Vrancken, Mann, Ritse M., Sonke, Gabe S.
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen
Published in Nature medicine (01.07.2019)
Published in Nature medicine (01.07.2019)
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PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial
Voorwerk, Leonie, Isaeva, Olga I, Horlings, Hugo M, Balduzzi, Sara, Chelushkin, Maksim, Bakker, Noor A M, Champanhet, Elisa, Garner, Hannah, Sikorska, Karolina, Loo, Claudette E, Kemper, Inge, Mandjes, Ingrid A M, de Maaker, Michiel, van Geel, Jasper J L, Boers, Jorianne, de Boer, Maaike, Salgado, Roberto, van Dongen, Marloes G J, Sonke, Gabe S, de Visser, Karin E, Schumacher, Ton N, Blank, Christian U, Wessels, Lodewyk F A, Jager, Agnes, Tjan-Heijnen, Vivianne C G, Schröder, Carolien P, Linn, Sabine C, Kok, Marleen
Published in Nature cancer (01.04.2023)
Published in Nature cancer (01.04.2023)
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