Synthesis and Pharmacological Evaluation of N-(3-(1H-Indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a Potent Antimitotic Agent
Shetty, Rupa S, Lee, Younghee, Liu, Bin, Husain, Arifa, Joseph, Rhoda W, Lu, Yixin, Nelson, David, Mihelcic, John, Chao, Wenchun, Moffett, Kristofer K, Schumacher, Andreas, Flubacher, Dietmar, Stojanovic, Aleksandar, Bukhtiyarova, Marina, Williams, Ken, Lee, Kyoung-Jin, Ochman, Alexander R, Saporito, Michael S, Moore, William R, Flynn, Gary A, Dorsey, Bruce D, Springman, Eric B, Fujimoto, Ted, Kelly, Martha J
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia
Kelly, Martha J, Pietranico-Cole, Sherrie, Larigan, J. Douglas, Haynes, Nancy-Ellen, Reynolds, Charles H, Scott, Nathan, Vermeulen, John, Dvorozniak, Mark, Conde-Knape, Karin, Huang, Kuo-Sen, So, Sung-Sau, Thakkar, Kshitij, Qian, Yimin, Banner, Bruce, Mennona, Frank, Danzi, Sara, Klein, Irwin, Taub, Rebecca, Tilley, Jefferson
Published in Journal of medicinal chemistry (22.05.2014)
Published in Journal of medicinal chemistry (22.05.2014)
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Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist
Taub, Rebecca, Chiang, Edward, Chabot-Blanchet, Malorie, Kelly, Martha J, Reeves, Richard A, Guertin, Marie-Claude, Tardif, Jean-Claude
Published in Atherosclerosis (01.10.2013)
Published in Atherosclerosis (01.10.2013)
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Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes
Michelotti, Enrique L., Moffett, Kristofer K., Nguyen, Duyan, Kelly, Martha J., Shetty, Rupa, Chai, Xiaomei, Northrop, Katrina, Namboodiri, Variketta, Campbell, Brandon, Flynn, Gary A., Fujimoto, Ted, Hollinger, Frank P., Bukhtiyarova, Marina, Springman, Eric B., Karpusas, Michael
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Stereochemistry of vinylallene cycloadditions
Reich, Hans J, Eisenhart, Eric K, Whipple, Wesley L, Kelly, Martha J
Published in Journal of the American Chemical Society (01.09.1988)
Published in Journal of the American Chemical Society (01.09.1988)
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Solid-phase synthesis of 1-substituted 4,5-dihydro-1,2,4-triazin-6-ones
Martı́nez-Teipel, Blanca, Michelotti, Enrique, Kelly, Martha J, Weaver, Damian G, Acholla, Francis, Beshah, Kebede, Teixidó, Jordi
Published in Tetrahedron letters (10.09.2001)
Published in Tetrahedron letters (10.09.2001)
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Silyl ketone chemistry. Preparation and reactions of silyl allenol ethers. Diels-Alder reaction of siloxy vinylallenes leading to sesquiterpenes
Reich, Hans J, Eisenhart, Eric K, Olson, Richard E, Kelly, Martha J
Published in Journal of the American Chemical Society (01.11.1986)
Published in Journal of the American Chemical Society (01.11.1986)
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Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes
Michelotti, Enrique L, Moffett, Kristofer K, Nguyen, Duyan, Kelly, Martha J, Shetty, Rupa, Chai, Xiaomei, Northrop, Katrina, Namboodiri, Variketta, Campbell, Brandon, Flynn, Gary A, Fujimoto, Ted, Hollinger, Frank P, Bukhtiyarova, Marina, Springman, Eric B, Karpusas, Michael
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF
KELLY, Martha J, WANG, Ping, HESTER, II, D. Keith, CHASNOFF, Anna, CHOI, Duk Soon, DUGUID, Robert J, CROW, Edwin L, SHU, Lianhe, DONG, Gang
Year of Publication 09.05.2024
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Year of Publication 09.05.2024
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METHOD OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF
KELLY, Martha J, WANG, Ping, HESTER, II, D. Keith, CHASNOFF, Anna, CHOI, Duk Soon, DUGUID, Robert J, CROW, Edwin L, SHU, Lianhe, DONG, Gang
Year of Publication 18.04.2024
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Year of Publication 18.04.2024
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METHODS OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF
KELLY, Martha J, WANG, Ping, HESTER, II, D. Keith, CHASNOFF, Anna, CHOI, Duk Soon, DUGUID, Robert J, CROW, Edwin L, SHU, Lianhe, DONG, Gang
Year of Publication 06.07.2023
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Year of Publication 06.07.2023
Patent
Methods of synthesizing thyroid hormone analogs and polymorphs thereof
Duguid, Robert J, Kelly, Martha J, Dong, Gang, Crow, Edwin L, Shu, Lianhe, Chasnoff, Anna, Choi, Duk Soon, Wang, Ping, Hester, II, D. Keith
Year of Publication 31.01.2023
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Year of Publication 31.01.2023
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METHODS OF SYNTHESIZING THYROID HORMONE ANALOGS AND POLYMORPHS THEREOF
KELLY, Martha J, WANG, Ping, HESTER, II, D. Keith, CHASNOFF, Anna, CHOI, Duk Soon, DUGUID, Robert J, CROW, Edwin L, SHU, Lianhe, DONG, Gang
Year of Publication 03.06.2021
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Year of Publication 03.06.2021
Patent
Methods of synthesizing thyroid hormone analogs and polymorphs thereof
Duguid, Robert J, Kelly, Martha J, Dong, Gang, Crow, Edwin L, Shu, Lianhe, Chasnoff, Anna, Choi, Duk Soon, Wang, Ping, Hester, II, D. Keith
Year of Publication 19.01.2021
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Year of Publication 19.01.2021
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ChemInform Abstract: Efficient Synthesis of 1,3,5-Trisubstituted Benzenes via Three Pd-Mediated Carbon-Sulfur, Carbon-Nitrogen and Carbon-Carbon Bond Formation Reactions
Liu, Bin, Shetty, Rupa S., Moffett, Kristofer K., Kelly, Martha J.
Published in ChemInform (12.07.2011)
Published in ChemInform (12.07.2011)
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