Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia
Andreeff, Michael, Kelly, Kevin R, Yee, Karen, Assouline, Sarit, Strair, Roger, Popplewell, Leslie, Bowen, David, Martinelli, Giovanni, Drummond, Mark W, Vyas, Paresh, Kirschbaum, Mark, Iyer, Swaminathan Padmanabhan, Ruvolo, Vivian, González, Graciela M Nogueras, Huang, Xuelin, Chen, Gong, Graves, Bradford, Blotner, Steven, Bridge, Peter, Jukofsky, Lori, Middleton, Steve, Reckner, Monica, Rueger, Ruediger, Zhi, Jianguo, Nichols, Gwen, Kojima, Kensuke
Published in Clinical cancer research (15.02.2016)
Published in Clinical cancer research (15.02.2016)
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CUDC-907 in relapsed/refractory diffuse large B-cell lymphoma, including patients with MYC-alterations: results from an expanded phase I trial
Oki, Yasuhiro, Kelly, Kevin R, Flinn, Ian, Patel, Manish R, Gharavi, Robert, Ma, Anna, Parker, Jefferson, Hafeez, Amir, Tuck, David, Younes, Anas
Published in Haematologica (Roma) (01.11.2017)
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Safety, tolerability, and preliminary activity of CUDC-907, a first-in-class, oral, dual inhibitor of HDAC and PI3K, in patients with relapsed or refractory lymphoma or multiple myeloma: an open-label, dose-escalation, phase 1 trial
Younes, Anas, Dr, Berdeja, Jesus G, MD, Patel, Manish R, MD, Flinn, Ian, MD, Gerecitano, John F, MD, Neelapu, Sattva S, MD, Kelly, Kevin R, MD, Copeland, Amanda R, MSN, Akins, Amy, BSN, Clancy, Myles S, MBA, Gong, Lucy, PharmD, Wang, Jing, PhD, Ma, Anna, MS, Viner, Jaye L, MD, Oki, Yasuhiro, MD
Published in The lancet oncology (01.05.2016)
Published in The lancet oncology (01.05.2016)
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Clinical use of proteasome inhibitors in the treatment of multiple myeloma
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Mechanisms of mTOR inhibitor resistance in cancer therapy
Carew, Jennifer S., Kelly, Kevin R., Nawrocki, Steffan T.
Published in Targeted oncology (01.03.2011)
Published in Targeted oncology (01.03.2011)
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Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma
Kelly, Kevin R, Friedberg, Jonathan W, Park, Steven I, McDonagh, Kevin, Hayslip, John, Persky, Daniel, Ruan, Jia, Puvvada, Soham, Rosen, Peter, Iyer, Swaminathan Padmanabhan, Stefanovic, Alexandra, Bernstein, Steven H, Weitman, Steven, Karnad, Anand, Monohan, Gregory, VanderWalde, Ari, Mena, Raul, Schmelz, Monika, Spier, Catherine, Groshen, Susan, Venkatakrishnan, Karthik, Zhou, Xiaofei, Sheldon-Waniga, Emily, Leonard, E Jane, Mahadevan, Daruka
Published in Clinical cancer research (15.12.2018)
Published in Clinical cancer research (15.12.2018)
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The NEDD8-activating enzyme inhibitor MLN4924 disrupts nucleotide metabolism and augments the efficacy of cytarabine
Nawrocki, Steffan T, Kelly, Kevin R, Smith, Peter G, Keaton, Mignon, Carraway, Hetty, Sekeres, Mikkael A, Maciejewski, Jaroslaw P, Carew, Jennifer S
Published in Clinical cancer research (15.01.2015)
Published in Clinical cancer research (15.01.2015)
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DeepDecon accurately estimates cancer cell fractions in bulk RNA-seq data
Huang, Jiawei, Du, Yuxuan, Stucky, Andres, Kelly, Kevin R., Zhong, Jiang F., Sun, Fengzhu
Published in Patterns (New York, N.Y.) (10.05.2024)
Published in Patterns (New York, N.Y.) (10.05.2024)
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Vorinostat Enhances the Activity of Temsirolimus in Renal Cell Carcinoma Through Suppression of Survivin Levels
MAHALINGAM, Devalingam, MEDINA, Ernest C, CAREW, Jennifer S, GILES, Francis J, NAWROCKI, Steffan T, ESQUIVEL, Juan A, ESPITIA, Claudia M, SMITH, Sabrina, OBERHEU, Kelli, SWORDS, Ronan, KELLY, Kevin R, MITA, Monica M, MITA, Alain C
Published in Clinical cancer research (01.01.2010)
Published in Clinical cancer research (01.01.2010)
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Targeting aurora kinases in cancer treatment
Kelly, Kevin R, Ecsedy, Jeffrey, Mahalingam, Devalingam, Nawrocki, Steffan T, Padmanabhan, Swaminathan, Giles, Francis J, Carew, Jennifer S
Published in Current drug targets (01.12.2011)
Published in Current drug targets (01.12.2011)
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A Phase IB multicentre dose‐determination study of BHQ880 in combination with anti‐myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal‐related events
Iyer, Swaminathan P., Beck, Joseph Taddeus, Stewart, A. Keith, Shah, Jatin, Kelly, Kevin R., Isaacs, Randi, Bilic, Sanela, Sen, Suman, Munshi, Nikhil C.
Published in British journal of haematology (01.11.2014)
Published in British journal of haematology (01.11.2014)
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Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial
Daver, Naval G., Dail, Monique, Garcia, Jacqueline S., Jonas, Brian A., Yee, Karen W. L., Kelly, Kevin R., Vey, Norbert, Assouline, Sarit, Roboz, Gail J., Paolini, Stefania, Pollyea, Daniel A., Tafuri, Agostino, Brandwein, Joseph M., Pigneux, Arnaud, Powell, Bayard L., Fenaux, Pierre, Olin, Rebecca L., Visani, Giuseppe, Martinelli, Giovanni, Onishi, Maika, Wang, Jue, Huang, Weize, Green, Cherie, Ott, Marion G., Hong, Wan-Jen, Konopleva, Marina Y., Andreeff, Michael
Published in Blood (16.03.2023)
Published in Blood (16.03.2023)
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A Phase I Study to Assess the Safety and Pharmacokinetics of Single-agent Lorvotuzumab Mertansine (IMGN901) in Patients with Relapsed and/or Refractory CD–56-positive Multiple Myeloma
Ailawadhi, Sikander, Kelly, Kevin R., Vescio, Robert A., Jagannath, Sundar, Wolf, Jeffrey, Gharibo, Mecide, Sher, Taimur, Bojanini, Leyla, Kirby, Maurice, Chanan-Khan, Asher
Published in Clinical lymphoma, myeloma and leukemia (01.01.2019)
Published in Clinical lymphoma, myeloma and leukemia (01.01.2019)
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The novel autophagy inhibitor ROC-325 augments the antileukemic activity of azacitidine
Nawrocki, Steffan T., Han, Yingchun, Visconte, Valeria, Przychodzen, Bartlomiej, Espitia, Claudia M., Phillips, James, Anwer, Faiz, Advani, Anjali, Carraway, Hetty E., Kelly, Kevin R., Sekeres, Mikkael A., Maciejewski, Jaroslaw P., Carew, Jennifer S.
Published in Leukemia (01.12.2019)
Published in Leukemia (01.12.2019)
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Efficacy and safety of bosutinib in previously treated patients with chronic myeloid leukemia: final results from the BYOND trial
Gambacorti-Passerini, Carlo, Brümmendorf, Tim H., Abruzzese, Elisabetta, Kelly, Kevin R., Oehler, Vivian G., García-Gutiérrez, Valentín, Hjorth-Hansen, Henrik, Ernst, Thomas, Leip, Eric, Purcell, Simon, Luscan, Gerald, Viqueira, Andrea, Giles, Francis J., Hochhaus, Andreas
Published in Leukemia (01.10.2024)
Published in Leukemia (01.10.2024)
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Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
Swords, Ronan T., Kelly, Kevin R., Smith, Peter G., Garnsey, James J., Mahalingam, Devalingam, Medina, Ernest, Oberheu, Kelli, Padmanabhan, Swaminathan, O'Dwyer, Michael, Nawrocki, Steffan T., Giles, Francis J., Carew, Jennifer S.
Published in Blood (06.05.2010)
Published in Blood (06.05.2010)
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Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial
Nawrocki, Steffan T, Olea, Julian, Villa Celi, Claudia, Dadrastoussi, Homa, Wu, Kaijin, Tsao-Wei, Denice, Colombo, Anthony, Coffey, Matt, Fernandez Hernandez, Eduardo, Chen, Xuelian, Nuovo, Gerard J, Carew, Jennifer S, Mohrbacher, Ann F, Fields, Paul, Kuhn, Peter, Siddiqi, Imran, Merchant, Akil, Kelly, Kevin R
Published in Clinical cancer research (15.12.2023)
Published in Clinical cancer research (15.12.2023)
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Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study
Yee, Karen, Papayannidis, Cristina, Vey, Norbert, Dickinson, Michael J., Kelly, Kevin R., Assouline, Sarit, Kasner, Margaret, Seiter, Karen, Drummond, Mark W., Yoon, Sung-Soo, Lee, Je-Hwan, Blotner, Steven, Jukofsky, Lori, Pierceall, William E., Zhi, Jianguo, Simon, Silke, Higgins, Brian, Nichols, Gwen, Monnet, Annabelle, Muehlbauer, Susanne, Ott, Marion, Chen, Lin-Chi, Martinelli, Giovanni
Published in Leukemia research (01.01.2021)
Published in Leukemia research (01.01.2021)
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