Development of a microphysiological model of human kidney proximal tubule function
Weber, Elijah J., Chapron, Alenka, Chapron, Brian D., Voellinger, Jenna L., Lidberg, Kevin A., Yeung, Catherine K., Wang, Zhican, Yamaura, Yoshiyuki, Hailey, Dale W., Neumann, Thomas, Shen, Danny D., Thummel, Kenneth E., Muczynski, Kimberly A., Himmelfarb, Jonathan, Kelly, Edward J.
Published in Kidney international (01.09.2016)
Published in Kidney international (01.09.2016)
Get full text
Journal Article
Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
Prasad, Bhagwat, Johnson, Katherine, Billington, Sarah, Lee, Caroline, Chung, Git W, Brown, Colin D A, Kelly, Edward J, Himmelfarb, Jonathan, Unadkat, Jashvant D
Published in Drug metabolism and disposition (01.12.2016)
Published in Drug metabolism and disposition (01.12.2016)
Get full text
Journal Article
Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
Basit, Abdul, Neradugomma, Naveen K, Wolford, Christopher, Fan, Peter W, Murray, Bernard, Takahashi, Ryan H, Khojasteh, S. Cyrus, Smith, Bill J, Heyward, Scott, Totah, Rheem A, Kelly, Edward J, Prasad, Bhagwat
Published in Molecular pharmaceutics (02.11.2020)
Published in Molecular pharmaceutics (02.11.2020)
Get full text
Journal Article
Human Enteroid Monolayers: A Novel, Functionally-Stable Model for Investigating Oral Drug Disposition
Arian, Christopher, O'Mahony, Eimear, MacDonald, James W, Bammler, Theo K, Donowitz, Mark, Kelly, Edward J, Thummel, Kenneth E
Published in Drug metabolism and disposition (09.08.2024)
Published in Drug metabolism and disposition (09.08.2024)
Get full text
Journal Article
A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro
Adler, Melanie, Ramm, Susanne, Hafner, Marc, Muhlich, Jeremy L, Gottwald, Esther Maria, Weber, Elijah, Jaklic, Alenka, Ajay, Amrendra Kumar, Svoboda, Daniel, Auerbach, Scott, Kelly, Edward J, Himmelfarb, Jonathan, Vaidya, Vishal S
Published in Journal of the American Society of Nephrology (01.04.2016)
Published in Journal of the American Society of Nephrology (01.04.2016)
Get full text
Journal Article
The development of an intestinal microphysiological system to model oral drug disposition
Arian, Christopher M, Kelly, Edward J, Thummel, Kenneth E
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
Get more information
Journal Article
CYP4V2 in Bietti's crystalline dystrophy: ocular localization, metabolism of ω-3-polyunsaturated fatty acids, and functional deficit of the p.H331P variant
Nakano, Mariko, Kelly, Edward J, Wiek, Constanze, Hanenberg, Helmut, Rettie, Allan E
Published in Molecular pharmacology (01.10.2012)
Published in Molecular pharmacology (01.10.2012)
Get full text
Journal Article
Endothelial dysfunction is dampened by early administration of fresh frozen plasma in a rodent burn shock model
Kelly, Edward J, Ziedins, Eriks E, Carney, Bonnie C, Moffatt, Lauren T, Shupp, Jeffrey W
Published in The journal of trauma and acute care surgery (01.10.2024)
Published in The journal of trauma and acute care surgery (01.10.2024)
Get more information
Journal Article
Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
Maass, Christian, Sorensen, Nathan B., Himmelfarb, Jonathan, Kelly, Edward J., Stokes, Cynthia L., Cirit, Murat
Published in CPT: pharmacometrics and systems pharmacology (01.05.2019)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2019)
Get full text
Journal Article
Expression and Characterization of CYP4V2 as a Fatty Acid ω-Hydroxylase
NAKANO, Mariko, KELLY, Edward J, RETTIE, Allan E
Published in Drug metabolism and disposition (01.11.2009)
Published in Drug metabolism and disposition (01.11.2009)
Get full text
Journal Article
Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system
Imaoka, Tomoki, Huang, Weize, Shum, Sara, Hailey, Dale W., Chang, Shih-Yu, Chapron, Alenka, Yeung, Catherine K., Himmelfarb, Jonathan, Isoherranen, Nina, Kelly, Edward J.
Published in Scientific reports (01.11.2021)
Published in Scientific reports (01.11.2021)
Get full text
Journal Article
Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling
Sakolish, Courtney, Chen, Zunwei, Dalaijamts, Chimeddulam, Mitra, Kusumica, Liu, Yina, Fulton, Tracy, Wade, Terry L., Kelly, Edward J., Rusyn, Ivan, Chiu, Weihsueh A.
Published in Toxicology in vitro (01.03.2020)
Published in Toxicology in vitro (01.03.2020)
Get full text
Journal Article