H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan, Tergaonkar, Vinay, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published in Nature communications (29.01.2021)
Published in Nature communications (29.01.2021)
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Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination
Wang, Jia, Ho, Wan Yun, Lim, Kenneth, Feng, Jia, Tucker-Kellogg, Greg, Nave, Klaus-Armin, Ling, Shuo-Chien
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (13.11.2018)
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Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction
Peng, Audrey Yi Tyan, Agrawal, Ira, Ho, Wan Yun, Yen, Yi-Chun, Pinter, Ashley J., Liu, Jerry, Phua, Qi Xuan Cheryl, Koh, Katrianne Bethia, Chang, Jer-Cherng, Sanford, Emma, Man, Jodie Hon Kiu, Wong, Peiyan, Gutmann, David H., Tucker-Kellogg, Greg, Ling, Shuo-Chien
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
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Journal Article
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination
Ho, Wan Yun, Chang, Jer-Cherng, Lim, Kenneth, Cazenave-Gassiot, Amaury, Nguyen, Aivi T, Foo, Juat Chin, Muralidharan, Sneha, Viera-Ortiz, Ashley, Ong, Sarah J M, Hor, Jin Hui, Agrawal, Ira, Hoon, Shawn, Arogundade, Olubankole Aladesuyi, Rodriguez, Maria J, Lim, Su Min, Kim, Seung Hyun, Ravits, John, Ng, Shi-Yan, Wenk, Markus R, Lee, Edward B, Tucker-Kellogg, Greg, Ling, Shuo-Chien
Published in The Journal of cell biology (06.09.2021)
Published in The Journal of cell biology (06.09.2021)
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
CARPTEN, John D, FABER, Andrew L, UHLIK, Mark, LIN, Aimin, JIAN DU, QIAN, Yue-Wei, ZECKNER, Douglas J, TUCKER-KELLOGG, Greg, TOUCHMAN, Jeffrey, PATEL, Ketan, MOUSSES, Spyro, BITTNER, Michael, HORN, Candice, SCHEVITZ, Richard, LAI, Mei-Huei T, BLANCHARD, Kerry L, THOMAS, James E, DONOHO, Gregory P, BRIGGS, Stephen L, ROBBINS, Christiane M, HOSTETTER, Galen, BOGUSLAWSKI, Sophie, MOSES, Tracy Y, SAVAGE, Stephanie
Published in Nature (26.07.2007)
Published in Nature (26.07.2007)
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Deep learning for de-convolution of Smad2 versus Smad3 binding sites
Ng, Jeremy W.K, Ong, Esther H.Q, Tucker-Kellogg, Lisa, Tucker-Kellogg, Greg
Published in BMC genomics (20.07.2022)
Published in BMC genomics (20.07.2022)
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A deeply conserved, noncanonical miRNA hosted by ribosomal DNA
Chak, Li-Ling, Mohammed, Jaaved, Lai, Eric C, Tucker-Kellogg, Greg, Okamura, Katsutomo
Published in RNA (Cambridge) (01.03.2015)
Published in RNA (Cambridge) (01.03.2015)
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Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development
Zhou, Li, Lim, Mandy Yu Theng, Kaur, Prameet, Saj, Abil, Bortolamiol-Becet, Diane, Gopal, Vikneswaran, Tolwinski, Nicholas, Tucker-Kellogg, Greg, Okamura, Katsutomo
Published in eLife (19.07.2018)
Published in eLife (19.07.2018)
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TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells
Chang, Kae-Jiun, Agrawal, Ira, Vainshtein, Anna, Ho, Wan Yun, Xin, Wendy, Tucker-Kellogg, Greg, Susuki, Keiichiro, Peles, Elior, Ling, Shuo-Chien, Chan, Jonah R
Published in eLife (10.03.2021)
Published in eLife (10.03.2021)
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Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma
Jeon, Ah-Jung, Teo, Yue-Yang, Sekar, Karthik, Chong, Shay Lee, Wu, Lingyan, Chew, Sin-Chi, Chen, Jianbin, Kendarsari, Raden Indah, Lai, Hannah, Ling, Wen Huan, Kaya, Neslihan Arife, Lim, Jia Qi, Ramasamy, Adaikalavan, Oguz, Gokce, Chung, Alexander Yaw-Fui, Chan, Chung Yip, Cheow, Peng-Chung, Kam, Juinn Huar, Madhavan, Krishnakumar, Kow, Alfred, Ganpathi, Iyer Shridhar, Lim, Tony Kiat Hon, Leow, Wei-Qiang, Loong, Shihleone, Loh, Tracy Jiezhen, Wan, Wei Keat, Soon, Gwyneth Shook Ting, Pang, Yin Huei, Yoong, Boon Koon, Ong, Diana Bee-Lan, Lim, Jasmine, de Villa, Vanessa H, Cruz, Rouchelle D Dela, Chanwat, Rawisak, Thammasiri, Jidapa, Bonney, Glenn K, Goh, Brian K P, Tucker-Kellogg, Greg, Foo, Roger Sik Yin, Chow, Pierce K H
Published in BMC cancer (03.02.2023)
Published in BMC cancer (03.02.2023)
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Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits
Ho, Wan Yun, Agrawal, Ira, Tyan, Sheue-Houy, Sanford, Emma, Chang, Wei-Tang, Lim, Kenneth, Ong, Jolynn, Tan, Bernice Siu Yan, Moe, Aung Aung Kywe, Yu, Regina, Wong, Peiyan, Tucker-Kellogg, Greg, Koo, Edward, Chuang, Kai-Hsiang, Ling, Shuo-Chien
Published in Acta neuropathologica communications (06.01.2021)
Published in Acta neuropathologica communications (06.01.2021)
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The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site
Lim, Mandy Yu Theng, Ng, Alvin Wei Tian, Chou, Yuting, Lim, Teck Por, Simcox, Amanda, Tucker-Kellogg, Greg, Okamura, Katsutomo
Published in Cell reports (Cambridge) (24.05.2016)
Published in Cell reports (Cambridge) (24.05.2016)
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Inferring pathway activity toward precise disease classification
Lee, Eunjung, Chuang, Han-Yu, Kim, Jong-Won, Ideker, Trey, Lee, Doheon
Published in PLoS computational biology (01.11.2008)
Published in PLoS computational biology (01.11.2008)
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TIP60-miR-22 axis as a prognostic marker of breast cancer progression
Pandey, Amit Kumar, Zhang, Yanzhou, Zhang, Siting, Li, Ying, Tucker-Kellogg, Greg, Yang, Henry, Jha, Sudhakar
Published in Oncotarget (01.12.2015)
Published in Oncotarget (01.12.2015)
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Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth
Zhang, Ying, Chen, Kaijing, Tang, Seng Chuan, Cai, Yichao, Nambu, Akiko, See, Yi Xiang, Fu, Chaoyu, Raju, Anandhkumar, Lebeau, Benjamin, Ling, Zixun, Chan, Jia Jia, Tay, Yvonne, Mutwil, Marek, Lakshmanan, Manikandan, Tucker-Kellogg, Greg, Chng, Wee Joo, Tenen, Daniel G, Osato, Motomi, Tergaonkar, Vinay, Fullwood, Melissa Jane
Published in Nature structural & molecular biology (20.09.2024)
Published in Nature structural & molecular biology (20.09.2024)
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