Presenilin-1 mutations and Alzheimer’s disease
Kelleher, Raymond J., Shen, Jie
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2017)
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Journal Article
Presenilin-1 Knockin Mice Reveal Loss-of-Function Mechanism for Familial Alzheimer’s Disease
Xia, Dan, Watanabe, Hirotaka, Wu, Bei, Lee, Sang Hun, Li, Yan, Tsvetkov, Evgeny, Bolshakov, Vadim Y., Shen, Jie, Kelleher, Raymond J.
Published in Neuron (Cambridge, Mass.) (04.03.2015)
Published in Neuron (Cambridge, Mass.) (04.03.2015)
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Journal Article
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
Tong, Youren, Yamaguchi, Hiroo, Giaime, Emilie, Boyle, Scott, Kopan, Raphael, Kelleher, Raymond J. III, Shen, Jie
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2010)
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Journal Article
Developing a Gene Therapy for the Treatment of Autosomal Dominant Alzheimer's Disease
Moore, Benjamin, Sharma, Apurwa, Goulet, Martin, Suter, Tracey, Pelletier, Carolyn, Hu, Ruoxi, Schaeffer, Eric, Kelleher, 3rd, Raymond J
Published in Human gene therapy (01.10.2023)
Published in Human gene therapy (01.10.2023)
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Journal Article
A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders
Carrette, Lieselot L. G., Wang, Chen-Yu, Wei, Chunyao, Press, William, Ma, Weiyuan, Kelleher, Raymond J., Lee, Jeannie T.
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (23.01.2018)
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Journal Article
High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism
Kelleher, 3rd, Raymond J, Geigenmüller, Ute, Hovhannisyan, Hayk, Trautman, Edwin, Pinard, Robert, Rathmell, Barbara, Carpenter, Randall, Margulies, David
Published in PloS one (27.04.2012)
Published in PloS one (27.04.2012)
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Journal Article
A clustered plasticity model of long-term memory engrams
Tonegawa, Susumu, Govindarajan, Arvind, Kelleher, Raymond J
Published in Nature reviews. Neuroscience (01.07.2006)
Published in Nature reviews. Neuroscience (01.07.2006)
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Journal Article
Translational Regulatory Mechanisms in Persistent Forms of Synaptic Plasticity
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Book Review
Journal Article
Humanized mouse model of ovarian cancer recapitulates patient solid tumor progression, ascites formation, and metastasis
Bankert, Richard B, Balu-Iyer, Sathy V, Odunsi, Kunle, Shultz, Leonard D, Kelleher, Jr, Raymond J, Barnas, Jennifer L, Simpson-Abelson, Michelle, Parsons, Robert, Yokota, Sandra J
Published in PloS one (15.09.2011)
Published in PloS one (15.09.2011)
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Journal Article
Translational Control by MAPK Signaling in Long-Term Synaptic Plasticity and Memory
Kelleher, Raymond J, Govindarajan, Arvind, Jung, Hae-Yoon, Kang, Hyejin, Tonegawa, Susumu
Published in Cell (06.02.2004)
Published in Cell (06.02.2004)
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Journal Article
A Presenilin-1 Mutation Identified in Familial Alzheimer Disease with Cotton Wool Plaques Causes a Nearly Complete Loss of γ-Secretase Activity
Heilig, Elizabeth A., Xia, Weiming, Shen, Jie, Kelleher, Raymond J.
Published in The Journal of biological chemistry (16.07.2010)
Published in The Journal of biological chemistry (16.07.2010)
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Journal Article
Sialic Acid-Dependent Inhibition of T Cells by Exosomal Ganglioside GD3 in Ovarian Tumor Microenvironments
Shenoy, Gautam N, Loyall, Jenni, Berenson, Charles S, Kelleher, Jr, Raymond J, Iyer, Vandana, Balu-Iyer, Sathy V, Odunsi, Kunle, Bankert, Richard B
Published in The Journal of immunology (1950) (15.12.2018)
Published in The Journal of immunology (1950) (15.12.2018)
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Journal Article
Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments
Bhatta, Maulasri, Shenoy, Gautam N, Loyall, Jenni L, Gray, Brian D, Bapardekar, Meghana, Conway, Alexis, Minderman, Hans, Kelleher Jr, Raymond J, Carreno, Beatriz M, Linette, Gerald, Shultz, Leonard D, Odunsi, Kunle, Balu-Iyer, Sathy V, Pak, Koon Yan, Bankert, Richard B
Published in Journal for immunotherapy of cancer (01.10.2021)
Published in Journal for immunotherapy of cancer (01.10.2021)
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Journal Article
Exosomes Represent an Immune Suppressive T Cell Checkpoint in Human Chronic Inflammatory Microenvironments
Shenoy, Gautam N, Bhatta, Maulasri, Loyall, Jenni L, Kelleher Jr, Raymond J, Bernstein, Joel M, Bankert, Richard B
Published in Immunological investigations (02.10.2020)
Published in Immunological investigations (02.10.2020)
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Journal Article
Tissue- and cell-type-specific molecular and functional signatures of 16p11.2 reciprocal genomic disorder across mouse brain and human neuronal models
Tai, Derek J.C., Razaz, Parisa, Erdin, Serkan, Gao, Dadi, Wang, Jennifer, Nuttle, Xander, de Esch, Celine E., Collins, Ryan L., Currall, Benjamin B., O’Keefe, Kathryn, Burt, Nicholas D., Yadav, Rachita, Wang, Lily, Mohajeri, Kiana, Aneichyk, Tatsiana, Ragavendran, Ashok, Stortchevoi, Alexei, Morini, Elisabetta, Ma, Weiyuan, Lucente, Diane, Hastie, Alex, Kelleher, Raymond J., Perlis, Roy H., Talkowski, Michael E., Gusella, James F.
Published in American journal of human genetics (06.10.2022)
Published in American journal of human genetics (06.10.2022)
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Journal Article
Characterization of Human Lung Tumor-Associated Fibroblasts and Their Ability to Modulate the Activation of Tumor-Associated T Cells
Nazareth, Michael R, Broderick, Lori, Simpson-Abelson, Michelle R, Kelleher, Raymond J., Jr, Yokota, Sandra J, Bankert, Richard B
Published in Journal of Immunology (01.05.2007)
Published in Journal of Immunology (01.05.2007)
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