Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice
Farrow, Emily G, Yu, Xijie, Summers, Lelia J, Davis, Siobhan I, Fleet, James C, Allen, Matthew R, Robling, Alexander G, Stayrook, Keith R, Jideonwo, Victoria, Magers, Martin J, Garringer, Holly J, Vidal, Ruben, Chan, Rebecca J, Goodwin, Charles B, Hui, Siu L, Peacock, Munro, White, Kenneth E
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2011)
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Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow
Clinkenbeard, Erica L, Hanudel, Mark R, Stayrook, Keith R, Appaiah, Hitesh Nidumanda, Farrow, Emily G, Cass, Taryn A, Summers, Lelia J, Ip, Colin S, Hum, Julia M, Thomas, Joseph C, Ivan, Mircea, Richine, Briana M, Chan, Rebecca J, Clemens, Thomas L, Schipani, Ernestina, Sabbagh, Yves, Xu, Linlin, Srour, Edward F, Alvarez, Marta B, Kacena, Melissa A, Salusky, Isidro B, Ganz, Tomas, Nemeth, Elizabeta, White, Kenneth E
Published in Haematologica (Roma) (01.11.2017)
Published in Haematologica (Roma) (01.11.2017)
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DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex
Zhang, Jun, Chalmers, Michael J, Stayrook, Keith R, Burris, Lorri L, Wang, Yongjun, Busby, Scott A, Pascal, Bruce D, Garcia-Ordonez, Ruben D, Bruning, John B, Istrate, Monica A, Kojetin, Douglas J, Dodge, Jeffrey A, Burris, Thomas P, Griffin, Patrick R
Published in Nature structural & molecular biology (01.05.2011)
Published in Nature structural & molecular biology (01.05.2011)
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HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions
Zheng, Jie, Chang, Mi Ra, Stites, Ryan E., Wang, Yong, Bruning, John B., Pascal, Bruce D., Novick, Scott J., Garcia-Ordonez, Ruben D., Stayrook, Keith R., Chalmers, Michael J., Dodge, Jeffrey A., Griffin, Patrick R.
Published in Nature communications (13.10.2017)
Published in Nature communications (13.10.2017)
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Journal Article
Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality
Shao, Yu, Wichern, Emily, Childress, Paul J, Adaway, Michele, Misra, Jagannath, Klunk, Angela, Burr, David B, Wek, Ronald C, Mosley, Amber L, Liu, Yunlong, Robling, Alexander G, Brustovetsky, Nickolay, Hamilton, James, Jacobs, Kylie, Vashishth, Deepak, Stayrook, Keith R, Allen, Matthew R, Wallace, Joseph M, Bidwell, Joseph P
Published in American journal of physiology: endocrinology and metabolism (01.05.2019)
Published in American journal of physiology: endocrinology and metabolism (01.05.2019)
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Regulation of Adipogenesis by Natural and Synthetic REV-ERB Ligands
Kumar, Naresh, Solt, Laura A, Wang, Yongjun, Rogers, Pamela M, Bhattacharyya, Gargi, Kamenecka, Theodore M, Stayrook, Keith R, Crumbley, Christine, Floyd, Z. Elizabeth, Gimble, Jeffrey M, Griffin, Patrick R, Burris, Thomas P
Published in Endocrinology (Philadelphia) (01.07.2010)
Published in Endocrinology (Philadelphia) (01.07.2010)
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Regulation of Carbohydrate Metabolism by the Farnesoid X Receptor
Stayrook, Keith R, Bramlett, Kelli S, Savkur, Rajesh S, Ficorilli, James, Cook, Todd, Christe, Michael E, Michael, Laura F, Burris, Thomas P
Published in Endocrinology (Philadelphia) (01.03.2005)
Published in Endocrinology (Philadelphia) (01.03.2005)
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Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis
Cao, Guoqing, Liang, Yu, Broderick, Carol L., Oldham, Brian A., Beyer, Thomas P., Schmidt, Robert J., Zhang, Youyan, Stayrook, Keith R., Suen, Chen, Otto, Keith A., Miller, Anne R., Dai, Jiannong, Foxworthy, Patricia, Gao, Hong, Ryan, Timothy P., Jiang, Xian-Cheng, Burris, Thomas P., Eacho, Patrick I., Etgen, Garret J.
Published in The Journal of biological chemistry (10.01.2003)
Published in The Journal of biological chemistry (10.01.2003)
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Journal Article
The Selective Alzheimer's Disease Indicator-1 Gene (Seladin-1/DHCR24) Is a Liver X Receptor Target Gene
Wang, Yongjun, Rogers, Pamela M, Stayrook, Keith R, Su, Chen, Varga, Gabor, Shen, Qi, Nagpal, Sunil, Burris, Thomas P
Published in Molecular pharmacology (01.12.2008)
Published in Molecular pharmacology (01.12.2008)
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The Hypolipidemic Natural Product Guggulsterone Is a Promiscuous Steroid Receptor Ligand
Burris, Thomas P, Montrose, Chahrzad, Houck, Keith A, Osborne, Harold E, Bocchinfuso, Wayne P, Yaden, Benjamin C, Cheng, Christine C, Zink, Richard W, Barr, Robert J, Hepler, Christoper D, Krishnan, Venkatesh, Bullock, Heather A, Burris, Lorri L, Galvin, Rachelle J, Bramlett, Kelli, Stayrook, Keith R
Published in Molecular pharmacology (01.03.2005)
Published in Molecular pharmacology (01.03.2005)
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Journal Article
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ
Burris, Thomas P, Huang, Pengxiang, Rastinejad, Fraydoon, Rogers, Pamela M, Khorasanizadeh, Sepideh, Raghuram, Srilatha, Stayrook, Keith R, McClure, Don B, Nosie, Amanda K, Burris, Lorri L
Published in Nature structural & molecular biology (01.12.2007)
Published in Nature structural & molecular biology (01.12.2007)
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Journal Article
Retinoid X Receptor Is a Nonsilent Major Contributor to Vitamin D Receptor-Mediated Transcriptional Activation
Bettoun, David J, Burris, Thomas P, Houck, Keith A, Buck, Donald W, Stayrook, Keith R, Khalifa, Berket, Lu, Jianfen, Chin, William W, Nagpal, Sunil
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2003)
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Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
Wang, Yongjun, Kumar, Naresh, Solt, Laura A, Richardson, Timothy I, Helvering, Leah M, Crumbley, Christine, Garcia-Ordonez, Ruben D, Stayrook, Keith R, Zhang, Xi, Novick, Scott, Chalmers, Michael J, Griffin, Patrick R, Burris, Thomas P
Published in The Journal of biological chemistry (12.02.2010)
Published in The Journal of biological chemistry (12.02.2010)
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Journal Article
Regulation of Cholesterologenesis by the Oxysterol Receptor, LXRα
Wang, Yongjun, Rogers, Pamela M., Su, Chen, Varga, Gabor, Stayrook, Keith R., Burris, Thomas P.
Published in The Journal of biological chemistry (26.09.2008)
Published in The Journal of biological chemistry (26.09.2008)
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Journal Article
Hydrogen/Deuterium Exchange Reveals Distinct Agonist/Partial Agonist Receptor Dynamics within Vitamin D Receptor/Retinoid X Receptor Heterodimer
Zhang, Jun, Chalmers, Michael J., Stayrook, Keith R., Burris, Lorri L., Garcia-Ordonez, Ruben D., Pascal, Bruce D., Burris, Thomas P., Dodge, Jeffery A., Griffin, Patrick R.
Published in Structure (London) (13.10.2010)
Published in Structure (London) (13.10.2010)
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Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt)
Lugar, Charles W, Clarke, Christian A, Morphy, Richard, Rudyk, Helene, Sapmaz, Selma, Stites, Ryan E, Vaught, Grant M, Furness, Kelly, Broughton, Howard B, Durst, Greg L, Clawson, David K, Stout, Stephanie L, Guo, Sherry Y, Durbin, Jim D, Stayrook, Keith R, Edmondson, Denise D, Kikly, Kristy, New, Nicole E, Bina, Holly A, Chambers, Mark G, Shetler, Pamela, Chang, William Y, Chang, Veavi Ching-Yun, Barr, Rob, Gough, Wendy H, Steele, Jimmy P, Getman, Brian, Patel, Nita, Mathes, Brian M, Richardson, Timothy I
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases
Buijs, Jeroen T., Stayrook, Keith R., Guise, Theresa A.
Published in Cancer microenvironment (01.12.2011)
Published in Cancer microenvironment (01.12.2011)
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Journal Article
Transcriptomic Analysis of Healthy and Atopic Dermatitis Samples Reveals the Role of IL-37 in Human Skin
Zhou, Jiajun, Gemperline, David C, Turner, Matthew J, Oldach, Jonathan, Molignano, Jennifer, Sims, Jonathan T, Stayrook, Keith R
Published in ImmunoHorizons (26.10.2021)
Published in ImmunoHorizons (26.10.2021)
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Journal Article
Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism
Shao, Yu, Hernandez-Buquer, Selene, Childress, Paul, Stayrook, Keith R, Alvarez, Marta B, Davis, Hannah, Plotkin, Lilian I, He, Yongzheng, Condon, Keith W, Burr, David B, Warden, Stuart J, Robling, Alexander G, Yang, Feng-Chun, Wek, Ronald C, Allen, Matthew R, Bidwell, Joseph P
Published in Endocrinology (Philadelphia) (01.09.2017)
Published in Endocrinology (Philadelphia) (01.09.2017)
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Journal Article
HDX reveals unique fragment ligands for the vitamin D receptor
Carson, Matthew W, Zhang, Jun, Chalmers, Michael J, Bocchinfuso, Wayne P, Holifield, Karol D, Masquelin, Thierry, Stites, Ryan E, Stayrook, Keith R, Griffin, Patrick R, Dodge, Jeffery A
Published in Bioorganic & medicinal chemistry letters (01.08.2014)
Published in Bioorganic & medicinal chemistry letters (01.08.2014)
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