Search Results - "Keily, Shazia" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases

Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases

by Jimenez, Juan-Miguel, Boyall, Dean, Brenchley, Guy, Collier, Philip N, Davis, Christopher J, Fraysse, Damien, Keily, Shazia B, Henderson, Jaclyn, Miller, Andrew, Pierard, Francoise, Settimo, Luca, Twin, Heather C, Bolton, Claire M, Curnock, Adam P, Chiu, Peter, Tanner, Adam J, Young, Stephen
Published in Journal of medicinal chemistry (14.03.2013)

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Journal Article

Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors

Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors

by Charrier, Jean-Damien, Miller, Andrew, Kay, David P, Brenchley, Guy, Twin, Heather C, Collier, Philip N, Ramaya, Sharn, Keily, Shazia B, Durrant, Steven J, Knegtel, Ronald M. A, Tanner, Adam J, Brown, Kieron, Curnock, Adam P, Jimenez, Juan-Miguel
Published in Journal of medicinal chemistry (14.04.2011)

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Journal Article

Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis

Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis

by Collier, Philip N, Twin, Heather C, Knegtel, Ronald M. A, Boyall, Dean, Brenchley, Guy, Davis, Christopher J, Keily, Shazia, Mak, Chau, Miller, Andrew, Pierard, Françoise, Settimo, Luca, Bolton, Clare M, Chiu, Peter, Curnock, Adam, Doyle, Elisabeth, Tanner, Adam J, Jimenez, Juan-Miguel
Published in ACS medicinal chemistry letters (08.08.2019)

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Journal Article

[1H-PYRAZOLO[3,4-B]PYRIDINE-4-YL]-PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

[1H-PYRAZOLO[3,4-B]PYRIDINE-4-YL]-PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

by MORTIMORE MICHAEL, KEILY SHAZIA, BOYALL DEAN, JIMENEZ JUAN MIGUEL, MILLER ANDREW, YOUNG STEPHEN, MAK CHAU, SETTIMO LUCA, BRENCHLEY GUY, TWIN HEATHER, DAVIS CHRISTOPHER, COLLIER PHILIP
Year of Publication 25.08.2010

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Patent

Thiophene-carboxamides useful as inhibitors of protein kinases

Thiophene-carboxamides useful as inhibitors of protein kinases

by DURRANT STEVEN, KEILY SHAZIA, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 05.02.2015

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Patent

Gcn2 inhibitors and uses thereof

Gcn2 inhibitors and uses thereof

by PORICHIS, FILIPPOS, KEILY, SHAZIA, MORTIMORE, MIKE, PULLIN, ROBERT, RUTHERFORD, ALISTAIR, DURRANT, STEVEN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, ENO, MEREDITH SUZANNE, DODD, JAMES, EVERITT, SIMON, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, MOCHALKIN, IGOR, BAILEY, ANDREW, NORTH, KIRI, XIAO, YUFANG
Year of Publication 01.10.2023

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Patent

Thiophene-carboxamides useful as inhibitors of protein kinases

Thiophene-carboxamides useful as inhibitors of protein kinases

by DURRANT STEVEN, KEILY SHAZIA, KAY DAVID, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 24.06.2014

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Patent

THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES

THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES

by DURRANT STEVEN, KEILY SHAZIA, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 21.11.2013

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Patent

Azaindazoles useful as inhibitors of kinases

Azaindazoles useful as inhibitors of kinases

by DURRANT STEVEN, KEILY SHAZIA, CAO JINGRONG, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 21.11.2013

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Patent

Thiophene-carboxamides useful as inhibitors of protein kinases

Thiophene-carboxamides useful as inhibitors of protein kinases

by DURRANT STEVEN, KEILY SHAZIA, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 09.07.2013

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Patent

Azaindazoles useful as inhibitors of kinases

Azaindazoles useful as inhibitors of kinases

by DURRANT STEVEN, KEILY SHAZIA, CAO JINGRONG, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 21.05.2013

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Patent

AZAINDAZOLES USEFUL AS INHIBITORS OF KINASES

AZAINDAZOLES USEFUL AS INHIBITORS OF KINASES

by DURRANT STEVEN, KEILY SHAZIA, CAO JINGRONG, CHARRIER JEAN-DAMIEN, BRENCHLEY GUY, KNEGTEL RONALD, RAMAYA SHARN
Year of Publication 28.06.2012

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Patent

Kinase inhibitors

Kinase inhibitors

by MORTIMORE MICHAEL, KEILY SHAZIA, DAVIS CHRIS, BOYALL DEAN, MILLER ANDREW, YOUNG STEPHEN, MAK CHAU, SETTIMO LUCA, BRENCHLEY GUY, JIMENEZ JUAN-MIGUEL, TWIN HEATHER, COLLIER PHILIP
Year of Publication 05.02.2013

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Patent

[1H- PYRAZOLO [3, 4-B]PYRIDINE-4-YL]-PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

[1H- PYRAZOLO [3, 4-B]PYRIDINE-4-YL]-PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

by KEILY, SHAZIA, BRENCHLEY, GUY, MILLER, ANDREW, MORTIMORE, MICHAEL, MAK, CHAU, TWIN, HEATHER, BOYALL, DEAN, JIMENEZ, JUAN-MIGUEL, COLLIER, PHILIP, SETTIMO, LUCA, DAVIS, CHRISTOPHER, YOUNG, STEPHEN
Year of Publication 27.06.2012

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Patent

KINASE INHIBITORS

KINASE INHIBITORS

by MORTIMORE MICHAEL, KEILY SHAZIA, DAVIS CHRIS, BOYALL DEAN, MILLER ANDREW, YOUNG STEPHEN, MAK CHAU, SETTIMO LUCA, BRENCHLEY GUY, JIMENEZ JUAN-MIGUEL, TWIN HEATHER, COLLIER PHILIP
Year of Publication 14.06.2012

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Patent

[1H- PYRAZOLO [3, 4-B] PYRIDINE-4-YL] -PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

[1H- PYRAZOLO [3, 4-B] PYRIDINE-4-YL] -PHENYLE OR -PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

by KEILY, SHAZIA, BRENCHLEY, GUY, MILLER, ANDREW, MORTIMORE, MICHAEL, MAK, CHAU, TWIN, HEATHER, BOYALL, DEAN, JIMENEZ, JUAN-MIGUEL, COLLIER, PHILIP, SETTIMO, LUCA, DAVIS, CHRISTOPHER, YOUNG, STEPHEN
Year of Publication 25.05.2012

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Patent

Kinase inhibitors

Kinase inhibitors

by Jimenez, Juan-Miguel, Mortimore, Michael, Miller, Andrew, Collier, Philip, Young, Stephen, Brenchley, Guy, Davis, Chris, Twin, Heather, Mak, Chau, Boyall, Dean, Keily, Shazia, Settimo, Luca
Year of Publication 08.05.2012

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Patent

Kinase inhibitors

Kinase inhibitors

by MORTIMORE MICHAEL, KEILY SHAZIA, DAVIS CHRIS, BOYALL DEAN, MILLER ANDREW, YOUNG STEPHEN, MAK CHAU, SETTIMO LUCA, BRENCHLEY GUY, JIMENEZ JUAN-MIGUEL, TWIN HEATHER, COLLIER PHILIP
Year of Publication 08.05.2012

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Patent

GCN2 inhibitors and uses thereof

GCN2 inhibitors and uses thereof

by PORICHIS, FILIPPOS, KEILY, SHAZIA, MORTIMORE, MIKE, PULLIN, ROBERT, RUTHERFORD, ALISTAIR, DURRANT, STEVEN, CHARRIER, JEAN-DAMIEN, ETXEBARRIA I JARDI, GORKA, ENO, MEREDITH SUZANNE, DODD, JAMES, EVERITT, SIMON, KNEGTEL, RONALD, TWIN, HEATHER, STORCK, PIERRE-HENRI, FRAYSSE, DAMIEN, MOCHALKIN, IGOR, BAILEY, ANDREW, NORTH, KIRI, XIAO, YUFANG
Year of Publication 01.11.2019

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Patent

[1H- PYRAZOLO [3, 4-B] PYRIDINE-4-YL] -PHENYLE OR PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

[1H- PYRAZOLO [3, 4-B] PYRIDINE-4-YL] -PHENYLE OR PYRIDIN-2-YLE DERIVATIVES AS PROTEIN KINASE C-THETA

by KEILY SHAZIA, MORTIMORE MICHAEL, BOYALL DEAN, MARK CHAU, YOUNG STEPHEN, MILLER ANDREW, SETTIMO LUCA, BRENCHLEY GUY, TWIN HEATHER, JIMENEZ JUAN-MIGUEL, COLLIER PHILIP, DAVID CHRISTOPHER KAMINSKI
Year of Publication 27.07.2011

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Patent