Fine tuning of cell signals by glycosylation
Furukawa, Koichi, Ohkawa, Yuki, Yamauchi, Yoshio, Hamamura, Kazunori, Ohmi, Yuhsuke, Furukawa, Keiko
Published in Journal of biochemistry (Tokyo) (01.06.2012)
Published in Journal of biochemistry (Tokyo) (01.06.2012)
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Journal Article
Binding of a Sialic Acid-recognizing Lectin Siglec-9 Modulates Adhesion Dynamics of Cancer Cells via Calpain-mediated Protein Degradation
Sabit, Ilhamjan, Hashimoto, Noboru, Matsumoto, Yasuyuki, Yamaji, Toshiyuki, Furukawa, Keiko, Furukawa, Koichi
Published in The Journal of biological chemistry (06.12.2013)
Published in The Journal of biological chemistry (06.12.2013)
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Journal Article
Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides
Miyata, Maiko, Kambe, Mariko, Tajima, Orie, Moriya, Setsuko, Sawaki, Hiromichi, Hotta, Hiroshi, Kondo, Yuji, Narimatsu, Hisashi, Miyagi, Taeko, Furukawa, Koichi, Furukawa, Keiko
Published in Cancer science (01.12.2011)
Published in Cancer science (01.12.2011)
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Journal Article
Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis
Nogimori, Kenichi, Hori, Tomoko, Kawaguchi, Koji, Fukui, Takayuki, Mii, Shinji, Nakada, Hiroshi, Matsumoto, Yasuyuki, Yamauchi, Yoshio, Takahashi, Masahide, Furukawa, Keiko, Tetsuya, Okajima, Yokoi, Kohei, Hasegawa, Yoshinori, Furukawa, Koichi
Published in International journal of oncology (01.10.2016)
Published in International journal of oncology (01.10.2016)
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Journal Article
Deficits in cognitive function and hippocampal plasticity in GM2/GD2 synthase knockout mice
Sha, Sha, Zhou, Libin, Yin, Jun, Takamiya, Koga, Furukawa, Keiko, Furukawa, Koichi, Sokabe, Masahiro, Chen, Ling
Published in Hippocampus (01.04.2014)
Published in Hippocampus (01.04.2014)
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Journal Article
The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice
Greenshields, Kay N, Halstead, Susan K, Zitman, Femke M P, Rinaldi, Simon, Brennan, Kathryn M, O'Leary, Colin, Chamberlain, Luke H, Easton, Alistair, Roxburgh, Jennifer, Pediani, John, Furukawa, Koichi, Furukawa, Keiko, Goodyear, Carl S, Plomp, Jaap J, Willison, Hugh J
Published in The Journal of clinical investigation (01.03.2009)
Published in The Journal of clinical investigation (01.03.2009)
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Journal Article
GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft‐localization of gangliosides in a melanoma cell line
Dong, Yu, Ikeda, Kazutaka, Hamamura, Kazunori, Zhang, Qing, Kondo, Yuji, Matsumoto, Yasuyuki, Ohmi, Yuhsuke, Yamauchi, Yoshio, Furukawa, Keiko, Taguchi, Ryo, Furukawa, Koichi
Published in Cancer science (01.09.2010)
Published in Cancer science (01.09.2010)
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Journal Article
Ganglioside GD3 Promotes Cell Growth and Invasion through p130Cas and Paxillin in Malignant Melanoma Cells
Hamamura, Kazunori, Furukawa, Keiko, Hayashi, Takanori, Hattori, Takeshi, Nakano, Junji, Nakashima, Hideyuki, Okuda, Tetsuya, Mizutani, Hideki, Hattori, Hisashi, Ueda, Minoru, Urano, Takeshi, Lloyd, Kenneth O., Furukawa, Koichi, Hakomori, Sen-itiroh
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2005)
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Journal Article
pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen
Matsumoto, Yasuyuki, Zhang, Qing, Akita, Kaoru, Nakada, Hiroshi, Hamamura, Kazunori, Tokuda, Noriyo, Tsuchida, Akiko, Matsubara, Takeshi, Hori, Tomoko, Okajima, Tetsuya, Furukawa, Keiko, Urano, Takeshi, Furukawa, Koichi
Published in Biochemical and biophysical research communications (02.03.2012)
Published in Biochemical and biophysical research communications (02.03.2012)
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Journal Article
Overexpressed GM1 Suppresses Nerve Growth Factor (NGF) Signals by Modulating the Intracellular Localization of NGF Receptors and Membrane Fluidity in PC12 Cells
Nishio, Masashi, Fukumoto, Satoshi, Furukawa, Keiko, Ichimura, Akiko, Miyazaki, Hiroshi, Kusunoki, Susumu, Urano, Takeshi, Furukawa, Koichi
Published in The Journal of biological chemistry (06.08.2004)
Published in The Journal of biological chemistry (06.08.2004)
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Journal Article
Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling
Ohkawa, Yuki, Ohmi, Yuhsuke, Tajima, Orie, Yamauchi, Yoshio, Furukawa, Keiko, Furukawa, Koichi
Published in Biochemical and biophysical research communications (05.08.2011)
Published in Biochemical and biophysical research communications (05.08.2011)
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Journal Article
Interfacial Interactions between Calcined Hydroxyapatite Nanocrystals and Substrates
Okada, Masahiro, Furukawa, Keiko, Serizawa, Takeshi, Yanagisawa, Yoshihiko, Tanaka, Hidekazu, Kawai, Tomoji, Furuzono, Tsutomu
Published in Langmuir (02.06.2009)
Published in Langmuir (02.06.2009)
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Journal Article
Overexpression of caveolin‐1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties
Nakashima, Hideyuki, Hamamura, Kazunori, Houjou, Toshiaki, Taguchi, Ryo, Yamamoto, Noriyuki, Mitsudo, Kenji, Tohnai, Iwai, Ueda, Minoru, Urano, Takeshi, Furukawa, Keiko, Furukawa, Koichi
Published in Cancer science (01.04.2007)
Published in Cancer science (01.04.2007)
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Journal Article
Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells
Hamamura, Kazunori, Tsuji, Momoko, Ohkawa, Yuki, Nakashima, Hideyuki, Miyazaki, Sayaka, Urano, Takeshi, Yamamoto, Noriyuki, Ueda, Minoru, Furukawa, Koichi, Furukawa, Keiko
Published in Biochimica et biophysica acta (01.03.2008)
Published in Biochimica et biophysica acta (01.03.2008)
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Journal Article
Overexpression of GD1a Ganglioside Sensitizes Motor Nerve Terminals to Anti-GD1a Antibody-Mediated Injury in a Model of Acute Motor Axonal Neuropathy
Goodfellow, John A, Bowes, Tyrone, Sheikh, Kazim, Odaka, Masaaki, Halstead, Susan K, Humphreys, Peter D, Wagner, Eric R, Yuki, Nobuhiro, Furukawa, Koichi, Furukawa, Keiko, Plomp, Jaap J, Willison, Hugh J
Published in The Journal of neuroscience (16.02.2005)
Published in The Journal of neuroscience (16.02.2005)
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Journal Article
Metastatic Potential of Mouse Lewis Lung Cancer Cells Is Regulated via Ganglioside GM1 by Modulating the Matrix Metalloprotease-9 Localization in Lipid Rafts
Zhang, Qing, Furukawa, Keiko, Chen, Ho-Hsiang, Sakakibara, Takumi, Urano, Takeshi, Furukawa, Koichi
Published in The Journal of biological chemistry (30.06.2006)
Published in The Journal of biological chemistry (30.06.2006)
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Journal Article
Overexpression of Ganglioside GM1 Results in the Dispersion of Platelet-derived Growth Factor Receptor from Glycolipid-enriched Microdomains and in the Suppression of Cell Growth Signals
Mitsuda, Teruhiko, Furukawa, Keiko, Fukumoto, Satoshi, Miyazaki, Hiroshi, Urano, Takeshi, Furukawa, Koichi
Published in The Journal of biological chemistry (29.03.2002)
Published in The Journal of biological chemistry (29.03.2002)
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Journal Article
b-series Ganglioside Deficiency Exhibits No Definite Changes in the Neurogenesis and the Sensitivity to Fas-mediated Apoptosis but Impairs Regeneration of the Lesioned Hypoglossal Nerve
Okada, Masahiko, Itoh, Michi-ichiro, Haraguchi, Masashi, Okajima, Tetsuya, Inoue, Masahiro, Oishi, Hideto, Matsuda, Yoichi, Iwamoto, Tsutomu, Kawano, Toshihiro, Fukumoto, Satoshi, Miyazaki, Hiroshi, Furukawa, Keiko, Aizawa, Shinichi, Furukawa, Koichi
Published in The Journal of biological chemistry (18.01.2002)
Published in The Journal of biological chemistry (18.01.2002)
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Journal Article
Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3
Ohkawa, Yuki, Miyazaki, Sayaka, Miyata, Maiko, Hamamura, Kazunori, Furukawa, Koichi, Furukawa, Keiko
Published in Biochemical and biophysical research communications (15.08.2008)
Published in Biochemical and biophysical research communications (15.08.2008)
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Journal Article
Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x
Hotta, Hiroshi, Hamamura, Kazunori, Yamashita, Kyoko, Shibuya, Hidenobu, Tokuda, Noriyo, Hashimoto, Noboru, Furukawa, Keiko, Yamamoto, Noriyuki, Hattori, Hisashi, Toyokuni, Shinya, Ueda, Minoru, Furukawa, Koichi
Published in Glycoconjugate journal (01.08.2013)
Published in Glycoconjugate journal (01.08.2013)
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Journal Article