RAIN study: a protocol for a randomised controlled trial evaluating efficacy, safety and cost-effectiveness of intravenous-to-oral antibiotic switch therapy in neonates with a probable bacterial infection
Keij, Fleur M, Kornelisse, René F, Hartwig, Nico G, Mauff, Katya, Poley, Marten J, Allegaert, Karel, Reiss, Irwin K M, Tramper-Stranders, Gerdien A
Published in BMJ open (01.07.2019)
Published in BMJ open (01.07.2019)
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Journal Article
Stratified Management for Bacterial Infections in Late Preterm and Term Neonates: Current Strategies and Future Opportunities Toward Precision Medicine
Keij, Fleur M, Achten, Niek B, Tramper-Stranders, Gerdien A, Allegaert, Karel, van Rossum, Annemarie M C, Reiss, Irwin K M, Kornelisse, René F
Published in Frontiers in pediatrics (01.04.2021)
Published in Frontiers in pediatrics (01.04.2021)
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Journal Article
Zebrafish larvae as experimental model to expedite the search for new biomarkers and treatments for neonatal sepsis
Keij, Fleur M., Koch, Bjørn E. V., Lozano Vigario, Fernando, Simons, Sinno H. P., van Hasselt, Johan G. C., Taal, H. Rob, Knibbe, C. A. J., Spaink, Herman P., Reiss, Irwin K. M., Krekels, Elke H. J.
Published in Journal of clinical and translational science (2021)
Published in Journal of clinical and translational science (2021)
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Journal Article
Challenges in developing a consensus definition of neonatal sepsis
McGovern, Matthew, Giannoni, Eric, Kuester, Helmut, Turner, Mark A., van den Hoogen, Agnes, Bliss, Joseph M., Koenig, Joyce M., Keij, Fleur M., Mazela, Jan, Finnegan, Rebecca, Degtyareva, Marina, Simons, Sinno H. P., de Boode, Willem P., Strunk, Tobias, Reiss, Irwin K. M., Wynn, James L., Molloy, Eleanor J.
Published in Pediatric research (01.07.2020)
Published in Pediatric research (01.07.2020)
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Journal Article
Neonatal sepsis: need for consensus definition, collaboration and core outcomes
Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyareva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J., Reiss, Irwin K. M.
Published in Pediatric research (01.07.2020)
Published in Pediatric research (01.07.2020)
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Journal Article
Neonatal sepsis definitions from randomised clinical trials
Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O’Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B., Strunk, Tobias, de Boode, Willem P., Polin, Richard, Wynn, James L., Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J., Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph, Koenig, Joyce M., Turner, Mark A., Gale, Christopher, Molloy, Eleanor J.
Published in Pediatric research (01.04.2023)
Published in Pediatric research (01.04.2023)
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Journal Article
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial
de Groot, Pieter F., Nikolic, Tatjana, Imangaliyev, Sultan, Bekkering, Siroon, Duinkerken, Gaby, Keij, Fleur M., Herrema, Hilde, Winkelmeijer, Maaike, Kroon, Jeffrey, Levin, Evgeni, Hutten, Barbara, Kemper, Elles M., Simsek, Suat, Levels, Johannes H. M., van Hoorn, Flora A., Bindraban, Renuka, Berkvens, Alicia, Dallinga-Thie, Geesje M., Davids, Mark, Holleman, Frits, Hoekstra, Joost B. L., Stroes, Erik S. G., Netea, Mihai, van Raalte, Daniël H., Roep, Bart O., Nieuwdorp, Max
Published in Diabetologia (01.03.2020)
Published in Diabetologia (01.03.2020)
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Journal Article
A Pooled Population Pharmacokinetic Study of Oral and Intravenous Administration of Clavulanic Acid in Neonates and Infants: Targeting Effective Beta-Lactamase Inhibition
Schouwenburg, Stef, Keij, Fleur M, Tramper-Stranders, Gerdien A, Kornelisse, René F, Reiss, Irwin K M, de Cock, Pieter A J G, Dhont, Evelyn, Watt, Kevin M, Muller, Anouk E, Flint, Robert B, Koch, Birgit C P, Allegaert, Karel, Preijers, Tim
Published in Clinical pharmacology and therapeutics (28.08.2024)
Published in Clinical pharmacology and therapeutics (28.08.2024)
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Journal Article
Pharmacokinetics of Clavulanic Acid in the Pediatric Population: A Systematic Literature Review
Keij, Fleur M., Tramper-Stranders, Gerdien A., Koch, Birgit C. P., Reiss, Irwin K. M., Muller, Anouk E., Kornelisse, René F., Allegaert, Karel
Published in Clinical pharmacokinetics (01.05.2022)
Published in Clinical pharmacokinetics (01.05.2022)
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Journal Article
Oral and Intravenous Amoxicillin Dosing Recommendations in Neonates: A Pooled Population Pharmacokinetic Study
Keij, Fleur M, Schouwenburg, Stef, Kornelisse, René F, Preijers, Tim, Mir, Fatima, Degraeuwe, Pieter, Stolk, Leo M, van Driel, Arianne, Kenter, Sandra, van der Sluijs, Jacqueline, Heidema, Jojanneke, den Butter, Paul C P, Reiss, Irwin K M, Allegaert, Karel, Tramper-Stranders, Gerdien A, Koch, Birgit C P, Flint, Robert B
Published in Clinical infectious diseases (30.11.2023)
Published in Clinical infectious diseases (30.11.2023)
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Journal Article
Correction: Neonatal sepsis definitions from randomised clinical trials
Hayes, Rían, Hartnett, Jack, Semova, Gergana, Murray, Cian, Murphy, Katherine, Carroll, Leah, Plapp, Helena, Hession, Louise, O'Toole, Jonathan, McCollum, Danielle, Roche, Edna, Jenkins, Elinor, Mockler, David, Hurley, Tim, McGovern, Matthew, Allen, John, Meehan, Judith, Plötz, Frans B, Strunk, Tobias, de Boode, Willem P, Polin, Richard, Wynn, James L, Degtyareva, Marina, Küster, Helmut, Janota, Jan, Giannoni, Eric, Schlapbach, Luregn J, Keij, Fleur M, Reiss, Irwin K M, Bliss, Joseph, Koenig, Joyce M, Turner, Mark A, Gale, Christopher, Molloy, Eleanor J
Published in Pediatric research (29.07.2024)
Published in Pediatric research (29.07.2024)
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Journal Article
Relapsing/remitting type 1 diabetes
van Megen, Kayleigh M., Spindler, Matthew P., Keij, Fleur M., Bosch, Ineke, Sprangers, Fleur, van Royen-Kerkhof, Annet, Nikolic, Tatjana, Roep, Bart O.
Published in Diabetologia (01.11.2017)
Published in Diabetologia (01.11.2017)
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Journal Article
Correction: Neonatal sepsis: need for consensus definition, collaboration and core outcomes
Molloy, Eleanor J., Wynn, James L., Bliss, Joseph, Koenig, Joyce M., Keij, Fleur M., McGovern, Matt, Kuester, Helmut, Turner, Mark A., Giannoni, Eric, Mazela, Jan, Degtyareva, Marina, Strunk, Tobias, Simons, Sinno H. P., Janota, Jan, Plotz, Franz B., van den Hoogen, Ages, de Boode, Willem, Schlapbach, Luregn J., Reiss, Irwin K. M.
Published in Pediatric research (01.07.2021)
Published in Pediatric research (01.07.2021)
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Journal Article
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial
Keij, Fleur M, Kornelisse, René F, Hartwig, Nico G, van der Sluijs-Bens, Jacqueline, van Beek, Ron H T, van Driel, Arianne, van Rooij, Linda G M, van Dalen-Vink, Ilka, Driessen, Gertjan J A, Kenter, Sandra, von Lindern, Jeannette S, Eijkemans, Marianne, Stam-Stigter, Gerda M, Qi, Hongchao, van den Berg, Maartje M, Baartmans, Martin G A, van der Meer-Kappelle, Laura H, Meijssen, Clemens B, Norbruis, Obbe F, Heidema, Jojanneke, van Rossem, Maaike C, den Butter, Paul C P, Allegaert, Karel, Reiss, Irwin K M, Tramper-Stranders, Gerdien A
Published in The lancet child & adolescent health (01.11.2022)
Published in The lancet child & adolescent health (01.11.2022)
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Journal Article
Neonatal sepsis: a systematic review of core outcomes from randomised clinical trials
Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M., Polin, Richard, Koenig, Joyce M., Turner, Mark A., Gale, Christopher, Molloy, Eleanor J.
Published in Pediatric research (01.03.2022)
Published in Pediatric research (01.03.2022)
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Journal Article