Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
Masson, Norma, Keeley, Thomas P, Giuntoli, Beatrice, White, Mark D, Puerta, Mikel Lavilla, Perata, Pierdomenico, Hopkinson, Richard J, Flashman, Emily, Licausi, Francesco, Ratcliffe, Peter J
Published in Science (American Association for the Advancement of Science) (05.07.2019)
Published in Science (American Association for the Advancement of Science) (05.07.2019)
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N-terminal cysteine acetylation and oxidation patterns may define protein stability
Heathcote, Karen C., Keeley, Thomas P., Myllykoski, Matti, Lundekvam, Malin, McTiernan, Nina, Akter, Salma, Masson, Norma, Ratcliffe, Peter J., Arnesen, Thomas, Flashman, Emily
Published in Nature communications (25.06.2024)
Published in Nature communications (25.06.2024)
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Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells
Wing, Peter A.C., Keeley, Thomas P., Zhuang, Xiaodong, Lee, Jeffrey Y., Prange-Barczynska, Maria, Tsukuda, Senko, Morgan, Sophie B., Harding, Adam C., Argles, Isobel L.A., Kurlekar, Samvid, Noerenberg, Marko, Thompson, Craig P., Huang, Kuan-Ying A., Balfe, Peter, Watashi, Koichi, Castello, Alfredo, Hinks, Timothy S.C., James, William, Ratcliffe, Peter J., Davis, Ilan, Hodson, Emma J., Bishop, Tammie, McKeating, Jane A.
Published in Cell reports (Cambridge) (20.04.2021)
Published in Cell reports (Cambridge) (20.04.2021)
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Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation
Warpsinski, Gabriela, Smith, Matthew J., Srivastava, Salil, Keeley, Thomas P., Siow, Richard C.M., Fraser, Paul A., Mann, Giovanni E.
Published in Redox biology (01.10.2020)
Published in Redox biology (01.10.2020)
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Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels
Sevimli, Gulsah, Smith, Matthew J., Caglar, Tuba Akgul, Bilir, Şükriye, Secilmis, Melike, Altun, Hamza Y., Yigit, Esra N., Yang, Fan, Keeley, Thomas P., Malli, Roland, Öztürk, Gürkan, Mann, Giovanni E., Eroglu, Emrah
Published in Redox biology (01.07.2022)
Published in Redox biology (01.07.2022)
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Corrigendum to “Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels” [Redox Biol. 53 (2022) 102319]
Sevimli, Gulsah, Smith, Matthew J., Caglar, Tuba Akgul, Bilir, Şükriye, Secilmis, Melike, Altun, Hamza Y., Yigit, Esra N., Yang, Fan, Keeley, Thomas P., Malli, Roland, Öztürk, Gürkan, Mann, Giovanni E., Eroglu, Emrah
Published in Redox biology (01.08.2022)
Published in Redox biology (01.08.2022)
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Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cells
Tian, Ya-Min, Holdship, Philip, To, Trang Quynh, Ratcliffe, Peter J., Keeley, Thomas P.
Published in The Journal of biological chemistry (01.09.2023)
Published in The Journal of biological chemistry (01.09.2023)
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Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels
Chapple, Sarah J., Keeley, Thomas P., Mastronicola, Daniela, Arno, Matthew, Vizcay-Barrena, Gema, Fleck, Roland, Siow, Richard C.M., Mann, Giovanni E.
Published in Free radical biology & medicine (01.03.2016)
Published in Free radical biology & medicine (01.03.2016)
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Hif-2α programs oxygen chemosensitivity in chromaffin cells
Prange-Barczynska, Maria, Jones, Holly A, Sugimoto, Yoichiro, Cheng, Xiaotong, Lima, Joanna Dcc, Ratnayaka, Indrika, Douglas, Gillian, Buckler, Keith J, Ratcliffe, Peter J, Keeley, Thomas P, Bishop, Tammie
Published in The Journal of clinical investigation (06.08.2024)
Published in The Journal of clinical investigation (06.08.2024)
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Reduced SERCA activity underlies dysregulation of Ca 2+ homeostasis under atmospheric O 2 levels
Keeley, Thomas P, Siow, Richard C M, Jacob, Ron, Mann, Giovanni E
Published in The FASEB journal (01.05.2018)
Published in The FASEB journal (01.05.2018)
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A PP2A-mediated feedback mechanism controls Ca 2+ -dependent NO synthesis under physiological oxygen
Keeley, Thomas P, Siow, Richard C M, Jacob, Ron, Mann, Giovanni E
Published in The FASEB journal (01.12.2017)
Published in The FASEB journal (01.12.2017)
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Hif-2[alpha] programs oxygen chemosensitivity in chromaffin cells
Prange-Barczynska, Maria, Jones, Holly A, Sugimoto, Yoichiro, Cheng, Xiaotong, Lima, Joanna D.C.C, Ratnayaka, Indrika, Douglas, Gillian, Buckler, Keith J, Ratcliffe, Peter J, Keeley, Thomas P, Bishop, Tammie
Published in The Journal of clinical investigation (15.09.2024)
Published in The Journal of clinical investigation (15.09.2024)
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P-288 - Nrf2 redox signalling in brain endothelial cells adapted to physiological O2: an in vitro model for ischaemia-reperfusion injury in stroke
Warpsinski, Gabriela, Srivastava, Salil, Keeley, Thomas P., Fraser, Paul, Mann, Giovanni E.
Published in Free radical biology & medicine (20.05.2018)
Published in Free radical biology & medicine (20.05.2018)
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Journal Article
L-13 - Redox regulation under physiological oxygen levels
Keeley, Thomas P., Chapple, Sarah J., Siow, Richard C.M., Jacob, Ron, Mann, Giovanni E.
Published in Free radical biology & medicine (20.05.2018)
Published in Free radical biology & medicine (20.05.2018)
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Journal Article
Nrf2 redox signalling in brain endothelial cells adapted to physiological O 2 : an in vitro model for ischaemia-reperfusion injury in stroke
Warpsinski, Gabriela, Srivastava, Salil, Keeley, Thomas P., Fraser, Paul, Mann, Giovanni E.
Published in Free radical biology & medicine (01.05.2018)
Published in Free radical biology & medicine (01.05.2018)
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Journal Article
Redox regulation under physiological oxygen levels
Keeley, Thomas P., Chapple, Sarah J., Siow, Richard C.M., Jacob, Ron, Mann, Giovanni E.
Published in Free radical biology & medicine (01.05.2018)
Published in Free radical biology & medicine (01.05.2018)
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