The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation
Hirschler-Laszkiewicz, Iwona, Chen, Shu-Jen, Bao, Lei, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Keefer, Kerry, Madesh, Muniswamy, Cheung, Joseph Y, Miller, Barbara A
Published in American Journal of Physiology: Cell Physiology (01.10.2018)
Published in American Journal of Physiology: Cell Physiology (01.10.2018)
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Journal Article
The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
Bao, Lei, Festa, Fernanda, Freet, Christopher S, Lee, John P, Hirschler-Laszkiewicz, Iwona M, Chen, Shu-Jen, Keefer, Kerry A, Wang, Hong-Gang, Patterson, Andrew D, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (01.10.2019)
Published in Scientific reports (01.10.2019)
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The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression
Bao, Lei, Festa, Fernanda, Hirschler-Laszkiewicz, Iwona, Keefer, Kerry, Wang, Hong-Gang, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (29.11.2022)
Published in Scientific reports (29.11.2022)
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Journal Article
The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1
Hirschler-Laszkiewicz, Iwona, Festa, Fernanda, Huang, Suming, Moldovan, George-Lucian, Nicolae, Claudia, Dhoonmoon, Ashna, Bao, Lei, Keefer, Kerry, Chen, Shu-Jen, Wang, Hong-Gang, Cheung, Joseph Y, Miller, Barbara A
Published in Scientific reports (15.04.2022)
Published in Scientific reports (15.04.2022)
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The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury
Miller, Barbara A, Wang, JuFang, Hirschler-Laszkiewicz, Iwona, Gao, Erhe, Song, Jianliang, Zhang, Xue-Qian, Koch, Walter J, Madesh, Muniswamy, Mallilankaraman, Karthik, Gu, Tongda, Chen, Shu-jen, Keefer, Kerry, Conrad, Kathleen, Feldman, Arthur M, Cheung, Joseph Y
Published in American journal of physiology. Heart and circulatory physiology (01.04.2013)
Published in American journal of physiology. Heart and circulatory physiology (01.04.2013)
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The Transient Receptor Potential (TRP) Channel TRPC3 TRP Domain and AMP-activated Protein Kinase Binding Site Are Required for TRPC3 Activation by Erythropoietin
Hirschler-Laszkiewicz, Iwona, Tong, Qin, Waybill, Kathleen, Conrad, Kathleen, Keefer, Kerry, Zhang, Wenyi, Chen, Shu-jen, Cheung, Joseph Y., Miller, Barbara A.
Published in The Journal of biological chemistry (02.09.2011)
Published in The Journal of biological chemistry (02.09.2011)
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Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion-sensitive and promotion-resistant genetic backgrounds
Feith, David J., Shantz, Lisa M., Shoop, Paula L., Keefer, Kerry A., Prakashagowda, Chethana, Pegg, Anthony E.
Published in Molecular carcinogenesis (01.06.2007)
Published in Molecular carcinogenesis (01.06.2007)
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Hyaluronan induces scarless repair in mouse limb organ culture
Iocono, Joseph A, Ehrlich, H.Paul, Keefer, Kerry A, Krummel, Thomas M
Published in Journal of pediatric surgery (01.04.1998)
Published in Journal of pediatric surgery (01.04.1998)
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Journal Article
Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics
Bao, Lei, Chen, Shu-jen, Conrad, Kathleen, Keefer, Kerry, Abraham, Thomas, Lee, John P., Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Wang, Hong-Gang, Dovat, Sinisa, Gans, Brian, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Published in The Journal of biological chemistry (18.11.2016)
Published in The Journal of biological chemistry (18.11.2016)
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A Splice Variant of the Human Ion Channel TRPM2 Modulates Neuroblastoma Tumor Growth through Hypoxia-inducible Factor (HIF)-1/2α
Chen, Shu-jen, Hoffman, Nicholas E., Shanmughapriya, Santhanam, Bao, Lei, Keefer, Kerry, Conrad, Kathleen, Merali, Salim, Takahashi, Yoshinori, Abraham, Thomas, Hirschler-Laszkiewicz, Iwona, Wang, JuFang, Zhang, Xue-Qian, Song, Jianliang, Barrero, Carlos, Shi, Yuguang, Kawasawa, Yuka Imamura, Bayerl, Michael, Sun, Tianyu, Barbour, Mustafa, Wang, Hong-Gang, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Published in The Journal of biological chemistry (26.12.2014)
Published in The Journal of biological chemistry (26.12.2014)
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Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy
Chen, Shu-Jen, Bao, Lei, Keefer, Kerry, Shanmughapriya, Santhanam, Chen, Longgui, Lee, John, Wang, JuFang, Zhang, Xue-Qian, Hirschler-Laszkiewicz, Iwona, Merali, Salim, Merali, Carmen, Imamura, Yuka, Dovat, Sinisa, Madesh, Muniswamy, Cheung, Joseph Y, Wang, Hong-Gang, Miller, Barbara A
Published in Cell death & disease (20.04.2020)
Published in Cell death & disease (20.04.2020)
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Vanadate ingestion increases the gain in wound breaking strength and leads to better organized collagen fibers in rats during healing
Ehrlich, H P, Keefer, K A, Maish, 3rd, G O, Myers, R L, Mackay, D R
Published in Plastic and reconstructive surgery (1963) (01.02.2001)
Published in Plastic and reconstructive surgery (1963) (01.02.2001)
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Abstract 1458: TRPM2 modulates neuroblastoma cell survival through Pyk2, CREB and MCU activation
Hirschler-Laszkiewicz, Iwona Malgorzata, Chen, Shu-jen, Bao, Lei, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Keefer, Kerry, Madesh, Muniswamy, Cheung, Joseph Y., Miller, Barbara A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 1324: TRPM2 promotes leukemia proliferation and survival through modulation of ROS and autophagy
Chen, Shu-Jen, Bao, Lei, Keefer, Kerry, Chen, Longgui, Wang, JuFang, Zhang, Xue-Qian, Shanmughapriya, Santhanam, Hirschler-Laszkiewicz, Iwona, Madesh, Muniswamy, Cheung, Joseph Y., Wang, Hong-Gang, Miller, Barbara A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
A simple method to assess the relative amount of collagen deposition in wounded fetal mouse limbs
Houghton, P E, Keefer, K A, Diegelmann, R F, Krummel, T M
Published in Wound repair and regeneration (01.10.1996)
Published in Wound repair and regeneration (01.10.1996)
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Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis
Hirschler-Laszkiewicz, Iwona, Zhang, Wenyi, Keefer, Kerry, Conrad, Kathleen, Tong, Qin, Chen, Shu-jen, Bronson, Sarah, Cheung, Joseph Y, Miller, Barbara A
Published in Experimental hematology (2012)
Published in Experimental hematology (2012)
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Journal Article
Vanadate and the Absence of Myofibroblasts in Wound Contraction
Ehrlich, H. Paul, Keefer, Kerry A, Myers, Roland L, Passaniti, Anthony
Published in Archives of surgery (Chicago. 1960) (01.05.1999)
Published in Archives of surgery (Chicago. 1960) (01.05.1999)
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Journal Article
TRPM2 Channels Protect Hearts from Ischemia-Reperfusion Injury
Cheung, Joseph Y., Wang, JuFang, Gao, Erhe, Song, Jianliang, Zhang, Xue-Qian, Muniswamy, Madesh, Mallilankaraman, Karthik, Chen, Shu-jen, Hirschler-Laszkiewicz, Iwona, Conrad, Kathleen, Keefer, Kerry, Feldman, Arthur M., Miller, Barbara A.
Published in Biophysical journal (29.01.2013)
Published in Biophysical journal (29.01.2013)
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