Approaching infinite affinity through engineering of peptide–protein interaction
Keeble, Anthony H., Turkki, Paula, Stokes, Samuel, Anuar, Irsyad N. A. Khairil, Rahikainen, Rolle, Hytönen, Vesa P., Howarth, Mark
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2019)
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Journal Article
SpyMask enables combinatorial assembly of bispecific binders
Driscoll, Claudia L, Keeble, Anthony H, Howarth, Mark R
Published in Nature communications (16.03.2024)
Published in Nature communications (16.03.2024)
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Journal Article
DogCatcher allows loop-friendly protein-protein ligation
Keeble, Anthony H., Yadav, Vikash K., Ferla, Matteo P., Bauer, Claudia C., Chuntharpursat-Bon, Eulashini, Huang, Jin, Bon, Robin S., Howarth, Mark
Published in Cell chemical biology (17.02.2022)
Published in Cell chemical biology (17.02.2022)
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Journal Article
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
Davies, Anna M., Allan, Elizabeth G., Keeble, Anthony H., Delgado, Jean, Cossins, Benjamin P., Mitropoulou, Alkistis N., Pang, Marie O.Y., Ceska, Tom, Beavil, Andrew J., Craggs, Graham, Westwood, Marta, Henry, Alistair J., McDonnell, James M., Sutton, Brian J.
Published in The Journal of biological chemistry (16.06.2017)
Published in The Journal of biological chemistry (16.06.2017)
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Journal Article
Paths reunited: Initiation of the classical and lectin pathways of complement activation
Wallis, Russell, Mitchell, Daniel A, Schmid, Ralf, Schwaeble, Wilhelm J, Keeble, Anthony H
Published in Immunobiology (1979) (01.01.2010)
Published in Immunobiology (1979) (01.01.2010)
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Journal Article
Structural Basis of Mannan-Binding Lectin Recognition by Its Associated Serine Protease MASP-1: Implications for Complement Activation
Gingras, Alexandre R., Girija, Umakhanth Venkatraman, Keeble, Anthony H., Panchal, Roshni, Mitchell, Daniel A., Moody, Peter C.E., Wallis, Russell
Published in Structure (London) (09.11.2011)
Published in Structure (London) (09.11.2011)
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Journal Article
Cytokinergic IgE Action in Mast Cell Activation
Bax, Heather J, Keeble, Anthony H, Gould, Hannah J
Published in Frontiers in immunology (01.01.2012)
Published in Frontiers in immunology (01.01.2012)
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Journal Article
Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E
Yuan, Daopeng, Keeble, Anthony H., Hibbert, Richard G., Fabiane, Stella, Gould, Hannah J., McDonnell, James M., Beavil, Andrew J., Sutton, Brian J., Dhaliwal, Balvinder
Published in The Journal of biological chemistry (26.07.2013)
Published in The Journal of biological chemistry (26.07.2013)
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Journal Article
Analogous Interactions in Initiating Complexes of the Classical and Lectin Pathways of Complement
Phillips, Anna E, Toth, Julia, Dodds, Alister W, Girija, Umakhanth Venkatraman, Furze, Christopher M, Pala, Eleni, Sim, Robert B, Reid, Kenneth B. M, Schwaeble, Wilhelm J, Schmid, Ralf, Keeble, Anthony H, Wallis, Russell
Published in The Journal of immunology (1950) (15.06.2009)
Published in The Journal of immunology (1950) (15.06.2009)
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Journal Article
Design and Evolution of Enhanced Peptide–Peptide Ligation for Modular Transglutaminase Assembly
Keeble, Anthony H., Wood, Dominic P., Howarth, Mark
Published in Bioconjugate chemistry (21.06.2023)
Published in Bioconjugate chemistry (21.06.2023)
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Journal Article
Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin
Rhodes, David A, Chen, Hung-Chang, Price, Amanda J, Keeble, Anthony H, Davey, Martin S, James, Leo C, Eberl, Matthias, Trowsdale, John
Published in The Journal of immunology (1950) (01.03.2015)
Published in The Journal of immunology (1950) (01.03.2015)
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Journal Article
Activation of Human gamma delta T Cells by Cytosolic Interactions of BTN3A1 with Soluble Phosphoantigens and the Cytoskeletal Adaptor Periplakin
Rhodes, David A, Chen, Hung-Chang, Price, Amanda J, Keeble, Anthony H, Davey, Martin S, James, Leo C, Eberl, Matthias, Trowsdale, John
Published in The Journal of immunology (1950) (01.03.2015)
Published in The Journal of immunology (1950) (01.03.2015)
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Journal Article
Highly Discriminating Protein–Protein Interaction Specificities in the Context of a Conserved Binding Energy Hotspot
Li, Wei, Keeble, Anthony H., Giffard, Catriona, James, Richard, Moore, Geoffery R., Kleanthous, Colin
Published in Journal of molecular biology (26.03.2004)
Published in Journal of molecular biology (26.03.2004)
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