Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice
Mistry, Akshitkumar M, Thompson, Christopher H, Miller, Alison R, Vanoye, Carlos G, George,, Alfred L, Kearney, Jennifer A
Published in Neurobiology of disease (01.05.2014)
Published in Neurobiology of disease (01.05.2014)
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Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome
Calhoun, Jeffrey D., Hawkins, Nicole A., Zachwieja, Nicole J., Kearney, Jennifer A.
Published in Epilepsia (Copenhagen) (01.08.2017)
Published in Epilepsia (Copenhagen) (01.08.2017)
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SCN3A‐Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation
Zaman, Tariq, Helbig, Katherine L., Clatot, Jérôme, Thompson, Christopher H., Kang, Seok Kyu, Stouffs, Katrien, Jansen, Anna E., Verstraete, Lieve, Jacquinet, Adeline, Parrini, Elena, Guerrini, Renzo, Fujiwara, Yuh, Miyatake, Satoko, Ben‐Zeev, Bruria, Bassan, Haim, Reish, Orit, Marom, Daphna, Hauser, Natalie, Vu, Thuy‐Anh, Ackermann, Sally, Spencer, Careni E., Lippa, Natalie, Srinivasan, Shraddha, Charzewska, Agnieszka, Hoffman‐Zacharska, Dorota, Fitzpatrick, David, Harrison, Victoria, Vasudevan, Pradeep, Joss, Shelagh, Pilz, Daniela T., Fawcett, Katherine A., Helbig, Ingo, Matsumoto, Naomichi, Kearney, Jennifer A., Fry, Andrew E., Goldberg, Ethan M.
Published in Annals of neurology (01.08.2020)
Published in Annals of neurology (01.08.2020)
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Journal Article
De novo KCNB1 mutations in epileptic encephalopathy
Torkamani, Ali, Bersell, Kevin, Jorge, Benjamin S., Bjork Jr, Robert L., Friedman, Jennifer R., Bloss, Cinnamon S., Cohen, Julie, Gupta, Siddharth, Naidu, Sakkubai, Vanoye, Carlos G., George Jr, Alfred L., Kearney, Jennifer A.
Published in Annals of neurology (01.10.2014)
Published in Annals of neurology (01.10.2014)
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Journal Article
Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome
Anderson, Lyndsey L., Hawkins, Nicole A., Thompson, Christopher H., Kearney, Jennifer A., George, Alfred L.
Published in Scientific reports (10.05.2017)
Published in Scientific reports (10.05.2017)
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Spectrum of KV2.1 Dysfunction in KCNB1‐Associated Neurodevelopmental Disorders
Kang, Seok Kyu, Vanoye, Carlos G., Misra, Sunita N., Echevarria, Dennis M., Calhoun, Jeffrey D., O'Connor, John B., Fabre, Katarina L., McKnight, Dianalee, Demmer, Laurie, Goldenberg, Paula, Grote, Lauren E., Thiffault, Isabelle, Saunders, Carol, Strauss, Kevin A., Torkamani, Ali, der Smagt, Jasper, Gassen, Koen, Carson, Robert P., Diaz, Jullianne, Leon, Eyby, Jacher, Joseph E., Hannibal, Mark C., Litwin, Jessica, Friedman, Neil R., Schreiber, Allison, Lynch, Bryan, Poduri, Annapurna, Marsh, Eric D., Goldberg, Ethan M., Millichap, John J., George, Alfred L., Kearney, Jennifer A.
Published in Annals of neurology (01.12.2019)
Published in Annals of neurology (01.12.2019)
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SCN3A deficiency associated with increased seizure susceptibility
Lamar, Tyra, Vanoye, Carlos G, Calhoun, Jeffrey, Wong, Jennifer C, Dutton, Stacey B.B, Jorge, Benjamin S, Velinov, Milen, Escayg, Andrew, Kearney, Jennifer A
Published in Neurobiology of disease (01.06.2017)
Published in Neurobiology of disease (01.06.2017)
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Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant
Hawkins, Nicole A., Misra, Sunita N, Jurado, Manuel, Kang, Seok Kyu, Vierra, Nicholas C., Nguyen, Kimberly, Wren, Lisa, George, Alfred L., Trimmer, James S., Kearney, Jennifer A.
Published in Neurobiology of disease (01.01.2021)
Published in Neurobiology of disease (01.01.2021)
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Journal Article
Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome
Anderson, Lyndsey L, Bahceci, Dilara A, Hawkins, Nicole A, Everett-Morgan, Declan, Banister, Samuel D, Kearney, Jennifer A, Arnold, Jonathon C
Published in PloS one (01.01.2023)
Published in PloS one (01.01.2023)
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Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent KCNB1-p.R306C voltage-sensor variant
Kang, Seok Kyu, Hawkins, Nicole A., Thompson, Christopher H., Baker, Erin M., Echevarria-Cooper, Dennis M., Barse, Levi, Thenstedt, Tyler, Dixon, Conor J., Speakes, Nathan, George, Alfred L., Kearney, Jennifer A.
Published in Neurobiology of disease (01.05.2024)
Published in Neurobiology of disease (01.05.2024)
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Novel SCN3A variants associated with focal epilepsy in children
Vanoye, Carlos G, Gurnett, Christina A, Holland, Katherine D, George, Alfred L, Kearney, Jennifer A
Published in Neurobiology of disease (01.02.2014)
Published in Neurobiology of disease (01.02.2014)
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Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Forrest, Marc P., Dos Santos, Marc, Piguel, Nicolas H., Wang, Yi-Zhi, Hawkins, Nicole A., Bagchi, Vikram A., Dionisio, Leonardo E., Yoon, Sehyoun, Simkin, Dina, Martin-de-Saavedra, Maria Dolores, Gao, Ruoqi, Horan, Katherine E., George, Alfred L., LeDoux, Mark S., Kearney, Jennifer A., Savas, Jeffrey N., Penzes, Peter
Published in Nature communications (17.02.2023)
Published in Nature communications (17.02.2023)
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The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a+/− Mouse Model of Dravet Syndrome
Satpute Janve, Vaishali, Anderson, Lyndsey L., Bahceci, Dilara, Hawkins, Nicole A., Kearney, Jennifer A., Arnold, Jonathon C.
Published in Frontiers in pharmacology (17.05.2021)
Published in Frontiers in pharmacology (17.05.2021)
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