Necroptosis is a novel mechanism of radiation-induced cell death in anaplastic thyroid and adrenocortical cancers
Nehs, Matthew A., MD, Lin, Chi-Iou, PhD, Kozono, David E., MD, PhD, Whang, Edward E., MD, Cho, Nancy L., MD, Zhu, Kaya, BS, Moalem, Jacob, MD, Moore, Francis D., MD, Ruan, Daniel T., MD
Published in Surgery (01.12.2011)
Published in Surgery (01.12.2011)
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Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression
Kozono, David, Jie Li, Masayuki Nitta, Oltea Sampetrean, David Gonda, Deepa S. Kushwaha, Dmitry Merzon, Valya Ramakrishnan, Shan Zhu, Kaya Zhu, Hiroko Matsui, Olivier Harismendy, Wei Hua, Ying Mao, Chang-Hyuk Kwon, Hideyuki Saya, Ichiro Nakano, Donald P. Pizzo, Scott R. VandenBerg, Clark C. Chen
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2015)
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Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer
Cron, Kyle R, Zhu, Kaya, Kushwaha, Deepa S, Hsieh, Grace, Merzon, Dmitry, Rameseder, Jonathan, Chen, Clark C, D'Andrea, Alan D, Kozono, David
Published in PloS one (05.09.2013)
Published in PloS one (05.09.2013)
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Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity
Ayrapetov, Marina K, Xu, Chang, Sun, Yingli, Zhu, Kaya, Parmar, Kalindi, D'Andrea, Alan D, Price, Brendan D
Published in PloS one (07.10.2011)
Published in PloS one (07.10.2011)
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USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1
Kushwaha, Deepa, O'Leary, Colin, Cron, Kyle R, Deraska, Peter, Zhu, Kaya, D'Andrea, Alan D, Kozono, David
Published in Cancer biology & therapy (04.03.2015)
Published in Cancer biology & therapy (04.03.2015)
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Abstract 1583: Proteasome inhibition as a strategy for non-small cell lung carcinoma via inhibition of DNA double strand break repair
Cron, Kyle R., Zhu, Kaya, Kushwaha, Deepa, Hsieh, Grace, Merzon, Dmitry, Monahan, Jack, Chen, Clark C., D'Andrea, Alan, Kozono, David
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 979: Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression
Li, Jie, Kozono, David, Nitta, Masayuki, Sampetrean, Oltea, Gonda, David, Kushwaha, Deepa S., Merzon, Dmitry, Ramakrishnan, Valya, Zhu, Shan, Zhu, Kaya, Matsui, Hiroko, Harismendy, Olivier, Hua, Wei, Mao, Ying, Kwon, Chang-Hyuk, Saya, Hideyuki, Carter, Bob S., Pizzo, Donald P., VandenBerg, Scott R., Chen, Clark C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death
Guinan, Eva C, Barbon, Christine M, Kalish, Leslie A, Parmar, Kalindi, Kutok, Jeff, Mancuso, Christy J, Stoler-Barak, Liat, Suter, Eugénie E, Russell, Janice D, Palmer, Christine D, Gallington, Leighanne C, Voskertchian, Annie, Vergilio, Jo-Anne, Cole, Geoffrey, Zhu, Kaya, D'Andrea, Alan, Soiffer, Robert, Weiss, Jerrold P, Levy, Ofer
Published in Science translational medicine (23.11.2011)
Published in Science translational medicine (23.11.2011)
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Abstract PR02: Dynamic epigenetic regulation of glioblastoma tumorigenicity through a LSD1-MYC-OLIG2 axis
Chen, Clark, Kozono, David, Li, Jie, Nitta, Masayuki, Sampetrean, Oltea, Ng, Kimberly, Gonda, David, Kushwaha, Deepa S., Merzon, Dmitry, Ramakrishnan, Valya, Zhu, Shan, Zhu, Kaya, Matsui, Hiroko, Harismendy, Olivier, Hua, Wei, Mao, Ying, Kwon, Chang-Hyuk, Ligon, Keith L., Saya, Hideyuki, Carter, Bob S., Pizzo, Donald P., VandenBerg, Scott R., Furnari, Frank, Cavenee, Webster
Published in Molecular cancer research (01.10.2015)
Published in Molecular cancer research (01.10.2015)
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Journal Article
Activation of Hif1[alpha] by the Prolylhydroxylase Inhibitor Dimethyoxalyglycine Decreases Radiosensitivity
Ayrapetov, Marina K, Xu, Chang, Sun, Yingli, Zhu, Kaya, Parmar, Kalindi, D'Andrea, Alan D, Price, Brendan D
Published in PloS one (07.10.2011)
Published in PloS one (07.10.2011)
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Abstract 1448: Whole genome RNAi screen identifies proteasome inhibition as a strategy for NSCLC radiosensitization
Zhu, Kaya, Kushwaha, Deepa, Cron, Kyle, Hsieh, Grace, Merzon, Dmitry, Evans, Daniel, Ng, Kimberly, Chen, Clark C., D'Andrea, Alan D., Kozono, David
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 5218: A c-Myc driven threshold model of tumor initiating in glioblastoma
Kozono, David, Nitta, Masayuki, Sampetrean, Oltea, Ng, Kimberly, Merzon, Dmitry, Kushwaha, Deepa, Zhu, Kaya, Ligon, Keith, Zhu, Shan, Saya, Hediyuki, Chen, Clark C.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 3301: c-Myc modulates the dynamic transition between tumor initiating states in glioblastoma
Kozono, David, Nitta, Masayuki, Ng, Kimberly, Zinn, Pascal O., Kushwaha, Deepa, Koay, Debbie, Merzon, Dmitry, Zhu, Kaya, Zhu, Shan, Ligon, Keith, Chen, Clark
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway
Mueller, Lars, Milsom, Michael D., Brumme, Kristina, Harris, Chad, Parmar, Kalindi, Zhu, Kaya, Wendy, London, Strait, Kelly, D'Andrea, Alan D., Daley, George Q., Williams, David A.
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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EPIG-02DYNAMIC EPIGENETIC MODULATION OF GLIOBLASTOMA TUMORIGENICITY BY INHIBITION OF LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1)
Kozono, David, Li, Jie, Sampetrean, Oltea, Gonda, David, Kushwaha, Deepa, Merzon, Dmitry, Nitta, Masayuki, Ramakrishnan, Valya, Zhu, Shan, Zhu, Kaya, Matsui, Hiroko, Harismendy, Olivier, Hua, Wei, Mao, Ying, Kwon, Chang-Hyuk, Saya, HIdeyuki, Nakano, Ichiro, Pizzo, Donald, Vandenberg, Scott, Chen, Clark
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
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Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models
Parmar, Kalindi, Kim, Jung Min, Shimamura, Akiko, Stuckert, Anna, DeLoach, Mary K, Zhu, Kaya, Mauch, Peter M., Kutok, Jeffery, Aster, Jon, Akashi, Koichi, Gilliland, D. Gary, D'Andrea, Alan D.
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer: e73710
Cron, Kyle R, Zhu, Kaya, Kushwaha, Deepa S, Hsieh, Grace, Merzon, Dmitry, Rameseder, Jonathan, Chen, Clark C, D'Andrea, Alan D, Kozono, David
Published in PloS one (01.09.2013)
Published in PloS one (01.09.2013)
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