The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo
Gu, Shuo, Jin, Lan, Zhang, Yue, Huang, Yong, Zhang, Feijie, Valdmanis, Paul N., Kay, Mark A.
Published in Cell (09.11.2012)
Published in Cell (09.11.2012)
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Journal Article
Drugging RNAi
Haussecker, Dirk, Kay, Mark A
Published in Science (American Association for the Advancement of Science) (06.03.2015)
Published in Science (American Association for the Advancement of Science) (06.03.2015)
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Journal Article
Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
Lisowski, Leszek, Dane, Allison P., Chu, Kirk, Zhang, Yue, Cunningham, Sharon C., Wilson, Elizabeth M., Nygaard, Sean, Grompe, Markus, Alexander, Ian E., Kay, Mark A.
Published in Nature (London) (20.02.2014)
Published in Nature (London) (20.02.2014)
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Journal Article
Human tRNA-derived small RNAs in the global regulation of RNA silencing
Haussecker, Dirk, Huang, Yong, Lau, Ashley, Parameswaran, Poornima, Fire, Andrew Z, Kay, Mark A
Published in RNA (Cambridge) (01.04.2010)
Published in RNA (Cambridge) (01.04.2010)
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Journal Article
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective
Sabatino, Denise E., Bushman, Frederic D., Chandler, Randy J., Crystal, Ronald G., Davidson, Beverly L., Dolmetsch, Ricardo, Eggan, Kevin C., Gao, Guangping, Gil-Farina, Irene, Kay, Mark A., McCarty, Douglas M., Montini, Eugenio, Ndu, Adora, Yuan, Jing
Published in Molecular therapy (03.08.2022)
Published in Molecular therapy (03.08.2022)
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Journal Article
Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs
Zhang, Feijie, Kay, Mark A, Sarnow, Peter, Gu, Shuo, Jin, Lan
Published in Nature structural & molecular biology (01.02.2009)
Published in Nature structural & molecular biology (01.02.2009)
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Journal Article
Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain
Gu, Shuo, Jin, Lan, Huang, Yong, Zhang, Feijie, Kay, Mark A.
Published in Current biology (21.08.2012)
Published in Current biology (21.08.2012)
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Journal Article
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
Malato, Yann, Naqvi, Syed, Schürmann, Nina, Ng, Raymond, Wang, Bruce, Zape, Joan, Kay, Mark A, Grimm, Dirk, Willenbring, Holger
Published in The Journal of clinical investigation (01.12.2011)
Published in The Journal of clinical investigation (01.12.2011)
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Journal Article
Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing
Wang, Yongming, PhD, Liang, Ping, MD, PhD, Lan, Feng, PhD, Wu, Haodi, PhD, Lisowski, Leszek, PhD, Gu, Mingxia, MD, PhD, Hu, Shijun, PhD, Kay, Mark A., MD, PhD, Urnov, Fyodor D., PhD, Shinnawi, Rami, PhD, Gold, Joseph D., PhD, Gepstein, Lior, MD, PhD, Wu, Joseph C., MD, PhD
Published in Journal of the American College of Cardiology (05.08.2014)
Published in Journal of the American College of Cardiology (05.08.2014)
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Journal Article
A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo
Chu, Jun, Oh, Younghee, Sens, Alex, Ataie, Niloufar, Dana, Hod, Macklin, John J, Laviv, Tal, Welf, Erik S, Dean, Kevin M, Zhang, Feijie, Kim, Benjamin B, Tang, Clement Tran, Hu, Michelle, Baird, Michelle A, Davidson, Michael W, Kay, Mark A, Fiolka, Reto, Yasuda, Ryohei, Kim, Douglas S, Ng, Ho-Leung, Lin, Michael Z
Published in Nature biotechnology (01.07.2016)
Published in Nature biotechnology (01.07.2016)
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Journal Article
RNA structure probing reveals the structural basis of Dicer binding and cleavage
Luo, Qing-Jun, Zhang, Jinsong, Li, Pan, Wang, Qing, Zhang, Yue, Roy-Chaudhuri, Biswajoy, Xu, Jianpeng, Kay, Mark A., Zhang, Qiangfeng Cliff
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice
Kim, Hak Kyun, Xu, Jianpeng, Chu, Kirk, Park, Hyesuk, Jang, Hagoon, Li, Pan, Valdmanis, Paul N., Zhang, Qiangfeng Cliff, Kay, Mark A.
Published in Cell reports (Cambridge) (17.12.2019)
Published in Cell reports (Cambridge) (17.12.2019)
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Journal Article
The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner
Gonzalez-Sandoval, Adriana, Pekrun, Katja, Tsuji, Shinnosuke, Zhang, Feijie, Hung, King L., Chang, Howard Y., Kay, Mark A.
Published in Nature communications (28.04.2023)
Published in Nature communications (28.04.2023)
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Journal Article
miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
Valdmanis, Paul N., Kim, Hak Kyun, Chu, Kirk, Zhang, Feijie, Xu, Jianpeng, Munding, Elizabeth M., Shen, Jia, Kay, Mark A.
Published in Nature communications (14.12.2018)
Published in Nature communications (14.12.2018)
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Journal Article
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
Grimm, Dirk, Streetz, Konrad L, Marion, Patricia, Storm, Theresa A, Salazar, Felix, Davis, Corrine R, Pandey, Kusum, Kay, Mark A, Jopling, Catherine L
Published in Nature (25.05.2006)
Published in Nature (25.05.2006)
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Journal Article
In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses
GRIMM, Dirk, LEE, Joyce S, WANG, Lora, DESAI, Tushar, AKACHE, Bassel, STORM, Theresa A, KAY, Mark A
Published in Journal of Virology (01.06.2008)
Published in Journal of Virology (01.06.2008)
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Journal Article
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase
Falcon, Alaric, Doege, Holger, Fluitt, Amy, Tsang, Bernice, Watson, Nicki, Kay, Mark A, Stahl, Andreas
Published in American journal of physiology: endocrinology and metabolism (01.09.2010)
Published in American journal of physiology: endocrinology and metabolism (01.09.2010)
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Journal Article
Robust expansion of human hepatocytes in Fah −/− / Rag2 −/− / Il2rg −/− mice
Grompe, Markus, Azuma, Hisaya, Paulk, Nicole, Ranade, Aarati, Dorrell, Craig, Al-Dhalimy, Muhsen, Ellis, Ewa, Strom, Stephen, Kay, Mark A, Finegold, Milton
Published in Nature biotechnology (01.08.2007)
Published in Nature biotechnology (01.08.2007)
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