Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing
Xue, Chaoyou, Salunkhe, Sameer J, Tomimatsu, Nozomi, Kawale, Ajinkya S, Kwon, Youngho, Burma, Sandeep, Sung, Patrick, Greene, Eric C
Published in Nature communications (26.04.2022)
Published in Nature communications (26.04.2022)
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DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation
Kwon, Youngho, Rösner, Heike, Zhao, Weixing, Selemenakis, Platon, He, Zhuoling, Kawale, Ajinkya S, Katz, Jeffrey N, Rogers, Cody M, Neal, Francisco E, Badamchi Shabestari, Aida, Petrosius, Valdemaras, Singh, Akhilesh K, Joel, Marina Z, Lu, Lucy, Holloway, Stephen P, Burma, Sandeep, Mukherjee, Bipasha, Hromas, Robert, Mazin, Alexander, Wiese, Claudia, Sørensen, Claus S, Sung, Patrick
Published in Nature communications (26.01.2023)
Published in Nature communications (26.01.2023)
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Journal Article
Persistent 3′-phosphate termini and increased cytotoxicity of radiomimetic DNA double-strand breaks in cells lacking polynucleotide kinase/phosphatase despite presence of an alternative 3′-phosphatase
Chalasani, Sri Lakshmi, Kawale, Ajinkya S., Akopiants, Konstantin, Yu, Yaping, Fanta, Mesfin, Weinfeld, Michael, Povirk, Lawrence F.
Published in DNA repair (01.08.2018)
Published in DNA repair (01.08.2018)
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Journal Article
Tumor cell escape from therapy-induced senescence
Saleh, Tareq, Tyutyunyk-Massey, Liliya, Murray, Graeme F., Alotaibi, Moureq R., Kawale, Ajinkya S., Elsayed, Zeinab, Henderson, Scott C., Yakovlev, Vasily, Elmore, Lynne W., Toor, Amir, Harada, Hisashi, Reed, Jason, Landry, Joseph W., Gewirtz, David A.
Published in Biochemical pharmacology (01.04.2019)
Published in Biochemical pharmacology (01.04.2019)
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Journal Article
Unprocessed genomic uracil as a source of DNA replication stress in cancer cells
Saxena, Sneha, Nabel, Christopher S., Seay, Turner W., Patel, Parasvi S., Kawale, Ajinkya S., Crosby, Caroline R., Tigro, Helene, Oh, Eugene, Vander Heiden, Matthew G., Hata, Aaron N., Suo, Zucai, Zou, Lee
Published in Molecular cell (06.06.2024)
Published in Molecular cell (06.06.2024)
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Journal Article
TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining
Kawale, Ajinkya S, Akopiants, Konstantin, Valerie, Kristoffer, Ruis, Brian, Hendrickson, Eric A, Huang, Shar-yin N, Pommier, Yves, Povirk, Lawrence F
Published in Nucleic acids research (28.09.2018)
Published in Nucleic acids research (28.09.2018)
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Journal Article
APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability
Kawale, Ajinkya S, Ran, Xiaojuan, Patel, Parasvi S, Saxena, Sneha, Lawrence, Michael S, Zou, Lee
Published in Science advances (19.01.2024)
Published in Science advances (19.01.2024)
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Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach
Saleh, Tareq, Tyutyunyk-Massey, Liliya, Murray, Graeme F., Alotaibi, Moureq R., Kawale, Ajinkya S., Elsayed, Zeinab, Henderson, Scott C., Yakovlev, Vasily, Elmore, Lynne W., Toor, Amir, Harada, Hisashi, Reed, Jason, Landry, Joseph W., Gewirtz, David A.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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