Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
Bhumireddy, Archana, Bandaru, N.V.M. Rao, Raghurami Reddy, B., Gore, Suraj T., Mukherjee, Subhendu, Balasubramanian, Wesley Roy, Sumanth Kumar, V., Alapati, Krishna Satya, Venkata Gowri Chandra Sekhar, Kondapalli, Nellore, Kavitha, Abbineni, Chandrasekhar, Samajdar, Susanta
Published in Bioorganic & medicinal chemistry letters (01.01.2022)
Published in Bioorganic & medicinal chemistry letters (01.01.2022)
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Journal Article
Synergistic inhibition of melanoma xenografts by Brequinar sodium and Doxorubicin
Dorasamy, Mathura Subangari, AB, Aravind, Nellore, Kavitha, Wong, Pooi-Fong
Published in Biomedicine & pharmacotherapy (01.02.2019)
Published in Biomedicine & pharmacotherapy (01.02.2019)
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Journal Article
Anticancer activity of Neptunia oleracea methanolic extracts
Bhumireddy, Archana, Nellore, Kavitha, Alapati, Krishna Satya
Published in Natural product research (01.02.2022)
Published in Natural product research (01.02.2022)
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Journal Article
Abstract 1713: Novel, potent and orally bioavailable small molecule CD73 inhibitors for cancer immunotherapy
Venkateshappa, Chandregowda, Narayanan, Kishore, Kothandaraman, Prasath, Priyadarshani, Garima, Nair, Rashmi, Goyal, Megha, Ahuja, Vijay Kamal, Dadhania, Sagar, Aravind, AB, Samiulla, DS, Daginakkatte, Girish, Antony, Thomas, Nellore, Kavitha, Panigrahi, Sunil, Chikkanna, Dinesh, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
COMPOUNDS AND COMPOSITIONS FOR TREATING HEMATOLOGICAL DISORDERS
SUSANTA SAMAJDAR, KAVITHA NELLORE, VENKATESHWAR RAO GUMMADI, WESLEY ROY BALASUBRAMANIAN, GIRISH DAGINAKATTE
Year of Publication 18.10.2023
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Year of Publication 18.10.2023
Patent
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase
McDonald, Gabrielle, Chubukov, Victor, Coco, John, Truskowski, Kevin, Narayanaswamy, Rohini, Choe, Sung, Steadman, Mya, Artin, Erin, Padyana, Anil K, Jin, Lei, Ronseaux, Sebastien, Locuson, Charles, Fan, Zi-Peng, Erdmann, Tabea, Mann, Alan, Hayes, Sebastian, Fletcher, Mark, Nellore, Kavitha, Rao, Siva Sanjeeva, Subramanya, Hosahalli, Reddy, K Satish, Panigrahi, Sunil K, Antony, Thomas, Gopinath, Sreevalsam, Sui, Zhihua, Nagaraja, Nelamangala, Dang, Lenny, Lenz, Georg, Hurov, Jonathan, Biller, Scott A, Murtie, Josh, Marks, Kevin M, Ulanet, Danielle B
Published in Molecular cancer therapeutics (01.12.2020)
Published in Molecular cancer therapeutics (01.12.2020)
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Journal Article
Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies
Gummadi, Venkateshwar Rao, Boruah, Anima, Ainan, Bharathi Raja, Vare, Brahma Reddy, Manda, Srinivas, Gondle, Hari Prakash, Kumar, Shiva Nagendra, Mukherjee, Subhendu, Gore, Suraj T, Krishnamurthy, Narasimha Rao, Marappan, Sivapriya, Nayak, Shilpa S, Nellore, Kavitha, Balasubramanian, Wesley Roy, Bhumireddy, Archana, Giri, Sanjeev, Gopinath, Sreevalsam, Samiulla, Dodheri S, Daginakatte, Girish, Basavaraju, Aravind, Chelur, Shekar, Eswarappa, Rajesh, Belliappa, Charamanna, Subramanya, Hosahalli S, Booher, Robert N, Ramachandra, Murali, Samajdar, Susanta
Published in ACS medicinal chemistry letters (10.12.2020)
Published in ACS medicinal chemistry letters (10.12.2020)
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Journal Article
Abstract 1143: Evaluation of AU-18069, a novel small molecule CBP/p300 bromodomain inhibitor for the treatment of cancers
Abbineni, Chandrasekhar, Thiyagarajan, Saravanan, Senaiar, Ramesh S, Mukherjee, Subhendu, Jaleel, Mahaboobi, Marappan, Sivapriya, N R, Raghavendra, Renukappa, Girish Aggunda, B, Aravind A, R, Naveen Kumar, Reddy, Venkata Siva, Babu, Asha, Srinivas, Akhila, Yadlapalli, Prasad, Gore, Suraj T, Hemasankar, Pathange, Dey, Mamon, S, Samiulla D, Naik, Chandranath D, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Myllymäki, Mikko, Wohlfahrt, Gerd, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1144: Orally bioavailable SMARCA2 degraders with exceptional selectivity and potency
Abbineni, Chandrasekhar, Satyam, Leena Khare, Kuila, Bilash, Ettam, Ashok, Rawoof, Khaji Abdul, MR, Sreevidya, Dukare, Sandeep Vitthal, Gore, Suraj T., Nankar, Rakesh P., Ahuja, Vijay Kamal, KB, Charamanna, Goyal, Megha, Aithal, Kiran, DS, Samiulla, Mukherjee, Subhendu, Antony, Thomas, Giri, Sanjeev, Chelur, Shekar, Nellore, Kavitha, Daginakatte, Girish, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1266: Discovery and preclinical evaluation of a novel covalent inhibitor of FABP5 for cancer therapy
Chikkanna, Dinesh, Satyam, Leena Khare, Pnaigrahi, Sunil Kumar, Khairnar, Vinayak, Pothuganti, Manoj, Kaza, Lakshmi Narayan, Kalidindi, Narasimha Raju, Nataraj, Vijaya Shankar, Gatta, Aditya Kiran, Krishnamurthy, Narasimha Rao, Patil, Sandeep, Samiulla, DS, Aithal, Kiran, Ahuja, Vijay Kamal, Tiwari, Nirbhay Kumar, Charamannna, KB, Pise, Pravin, Anthony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Chelur, Shekar, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Hematologic Malignancies Exhibit Selective Vulnerability to Inhibition of De Novo Pyrimidine Biosynthesis By AG-636, a Novel Inhibitor of Dihydroorotate Dehydrogenase in Phase 1 Clinical Trials
Ulanet, Danielle, Chubukov, Victor, Coco, John, McDonald, Gabrielle, Steadman, Mya, Narayanaswamy, Rohini, Ronseaux, Sebastien, Choe, Sung, Erdmann, Tabea, Truskowski, Kevin, Nellore, Kavitha, Rao, Siva Sanjeeva, Subramanya, Hosahalli, Lenz, Georg, Cooper, Michael, Murtie, Josh, Marks, Kevin
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Abstract 4030: Generation of profound anti-tumor immunity by AUR-109, a spectrum-selective tyrosine kinase inhibitor, either as a single agent or in combination with immune checkpoint inhibitors
Daginakatte, Girish, Thiyagarajan, Saravanan, Aithal, Kiran, Dey, Mamon, Reghu, Reshma, Mandal, Monalisha, Nellore, Kavitha, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH
Abdullah, Iskandar, Chee, Chin Fei, Lee, Yean-Kee, Thunuguntla, Siva Sanjeeva Rao, Satish Reddy, K., Nellore, Kavitha, Antony, Thomas, Verma, Jitender, Mun, Kong Wai, Othman, Shatrah, Subramanya, Hosahalli, Rahman, Noorsaadah Abd
Published in Bioorganic & medicinal chemistry (01.08.2015)
Published in Bioorganic & medicinal chemistry (01.08.2015)
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Journal Article
Abstract 4086: Preclinical evaluation of pharmacokinetics, pharmacodynamics and efficacy of the dual CD73-A2AR Inhibitors
Chikkanna, Dinesh, Narayanan, Kishore, Panigrahi, Sunil, Priyadarshini, Garima, Goyal, Megha, Mani, Jiju, Samiulla, DS, dadhania, Sagar, Aravind, AB, Daginakatte, Girish, Anthony, Thomas, Nellore, Kavitha, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1754: First in class orally bioavailable BETBRD degraders
Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Mukherjee, Subhendu, Marappan, Sivapriya, Tiwari, Nirbhay Kumar, Samiulla, DS, Aravind, AB, Kumar, Naveen R, Bansal, Indu, Reddy, Raghurami B, Bandaru, NVM Rao, Srinivas, Akhila, Maben, Janith Mary, Tgore, Suraj, Kumar, Avainash, Nankar, Rakesh P., Naik, Chandranath D., Antony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Daginakatte, Girish, Chelur, Shekar, Törmäkangas, Olli, Wohlfahrt, Gerd, Björkman, Mari, Mattila, Elina, Ravanti, Laura, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors
Jaleel, Mahaboobi, Senaiar, Ramesh S., Abbineni, Chandrasekhar, Renukappa, Girish A., Mukherjee, Subhendu, Marappan, Sivapriya, Samiulla, DS, Aravind, AB, Kumar, Naveen R., Reddy, Venkata Siva N., Babu, Asha, Srinivas, Akhila P., Yadlapalli, Prasad, Tgore, Suraj, NR, Raghavendra, Naik, Chandranath D., Giri, Sanjeev, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Ravanti, laura, Myllymäki, Mikko, Wohlfahrt, Gerd, Mattila, Elina, Karlsson, Stefan, Björkman, Mari, Riikonen, Reetta, Ikonen, Tarja, Leimu, Laura, Mälmström, Chira, Korjamo, Timo, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 3852: Combination efficacy and safety profile of an orally bioavailable small molecule agent targeting CD47/SIRPα axis
Daginakatte, Girish, Pottayil, Sasikumar, Chennakrishna, Gundala, Balasubramanian, Wesley Roy, Naremaddepalli, Sudarshan, Bhumireddy, Archana, Patil, Sandeep, Nellore, Kavitha, Chand, Priyabrata, Aithal, Kiran, Dhudashiya, Amit, DS, Samiulla, Eswarappa, Rajesh, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 6537: A novel CCR4 antagonist induces potent anti-tumor response through inhibition of Treg migration into the tumor microenvironment
Nair, Rashmi, Abbineni, Chandrasekhar, Talluri, Krishna Chaitanya, Dhudashiya, Amit A, AB, Aravind, R, Naveen Kumar, R, Ramya, Balasubramanyam, D, Obanna, Pathur, Madhaiyan, Rabin, Samiulla, DS, Daginakatte, Girish, Narayanan, Kishore, Nellore, Kavitha, Chelur, Shekar, Samajdar, Susanta, Ramachandra, Murali
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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