Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease
Lu, Hao, Galeano, Maria C Rondón, Ott, Elisabeth, Kaeslin, Geraldine, Kausalya, P Jaya, Kramer, Carina, Ortiz-Brüchle, Nadina, Hilger, Nadescha, Metzis, Vicki, Hiersche, Milan, Tay, Shang Yew, Tunningley, Robert, Vij, Shubha, Courtney, Andrew D, Whittle, Belinda, Wühl, Elke, Vester, Udo, Hartleben, Björn, Neuber, Steffen, Frank, Valeska, Little, Melissa H, Epting, Daniel, Papathanasiou, Peter, Perkins, Andrew C, Wright, Graham D, Hunziker, Walter, Gee, Heon Yung, Otto, Edgar A, Zerres, Klaus, Hildebrandt, Friedhelm, Roy, Sudipto, Wicking, Carol, Bergmann, Carsten
Published in Nature genetics (01.07.2017)
Published in Nature genetics (01.07.2017)
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Journal Article
Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis
Xu, Jianliang, Kausalya, P. Jaya, Van Hul, Noémi, Caldez, Matias J., Xu, Shiyi, Ong, Alicia Ghia Min, Woo, Wan Lu, Mohamed Ali, Safiah, Kaldis, Philipp, Hunziker, Walter
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Journal Article
Early Embryonic Lethality of Mice Lacking ZO-2, but Not ZO-3, Reveals Critical and Nonredundant Roles for Individual Zonula Occludens Proteins in Mammalian Development
Xu, Jianliang, Kausalya, P. Jaya, Phua, Dominic C. Y., Ali, Safiah Mohamed, Hossain, Zakir, Hunziker, Walter
Published in Molecular and Cellular Biology (01.03.2008)
Published in Molecular and Cellular Biology (01.03.2008)
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Journal Article
Claudin‐16 affects transcellular Cl− secretion in MDCK cells
Günzel, Dorothee, Amasheh, Salah, Pfaffenbach, Sandra, Richter, Jan F., Kausalya, P. Jaya, Hunziker, Walter, Fromm, Michael
Published in The Journal of physiology (01.08.2009)
Published in The Journal of physiology (01.08.2009)
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Journal Article
ZO-2/Tjp2 suppresses Yap and Wwtr1/Taz-mediated hepatocyte to cholangiocyte transdifferentiation in the mouse liver
Xu, Jianliang, Kausalya, P. Jaya, Ong, Alicia Ghia Min, Goh, Christine Meng Fan, Mohamed Ali, Safiah, Hunziker, Walter
Published in npj Regenerative medicine (23.09.2022)
Published in npj Regenerative medicine (23.09.2022)
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Journal Article
Convergent and Divergent Ligand Specificity among PDZ Domains of the LAP and Zonula Occludens (ZO) Families
Zhang, Yingnan, Yeh, Sherry, Appleton, Brent A., Held, Heike A., Kausalya, P. Jaya, Phua, Dominic C.Y., Lee Wong, Wai, Lasky, Laurence A., Wiesmann, Christian, Hunziker, Walter, Sidhu, Sachdev S.
Published in The Journal of biological chemistry (04.08.2006)
Published in The Journal of biological chemistry (04.08.2006)
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Journal Article
Single-Molecular-Level Study of Claudin-1-Mediated Adhesion
Lim, Tong Seng, Vedula, Sri Ram Krishna, Kausalya, P. Jaya, Hunziker, Walter, Lim, Chwee Teck
Published in Langmuir (15.01.2008)
Published in Langmuir (15.01.2008)
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Journal Article
Unusual Clinical Presentation and Possible Rescue of a Novel Claudin-16 Mutation
Müller, Dominik, Kausalya, P. Jaya, Bockenhauer, Detlef, Thumfart, Julia, Meij, Iwan C, Dillon, Michael J, Hoff, William van’t, Hunziker, Walter
Published in The journal of clinical endocrinology and metabolism (01.08.2006)
Published in The journal of clinical endocrinology and metabolism (01.08.2006)
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Journal Article
Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function
Günzel, Dorothee, Stuiver, Marchel, Kausalya, P. Jaya, Haisch, Lea, Krug, Susanne M, Rosenthal, Rita, Meij, Iwan C, Hunziker, Walter, Fromm, Michael, Müller, Dominik
Published in Journal of cell science (15.05.2009)
Published in Journal of cell science (15.05.2009)
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Journal Article
Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity
Yao, Fei, Kausalya, Jaya P., Sia, Yee Yen, Teo, Audrey S.M., Lee, Wah Heng, Ong, Alicia G.M., Zhang, Zhenshui, Tan, Joanna H.J., Li, Guoliang, Bertrand, Denis, Liu, Xingliang, Poh, Huay Mei, Guan, Peiyong, Zhu, Feng, Pathiraja, Thushangi Nadeera, Ariyaratne, Pramila N., Rao, Jaideepraj, Woo, Xing Yi, Cai, Shaojiang, Mulawadi, Fabianus H., Poh, Wan Ting, Veeravalli, Lavanya, Chan, Chee Seng, Lim, Seong Soo, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D., Chew, Elaine G.Y., Nagarajan, Niranjan, Jacques, Pierre-Étienne, So, Jimmy B.Y., Ruan, Xiaoan, Yeoh, Khay Guan, Tan, Patrick, Sung, Wing-Kin, Hunziker, Walter, Ruan, Yijun, Hillmer, Axel M.
Published in Cell reports (Cambridge) (14.07.2015)
Published in Cell reports (Cambridge) (14.07.2015)
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Journal Article
Portable Coulter counter with vertical through-holes for high-throughput applications
Chen, Yu, Kim, Seong-Jin, Guo, Jinhong, Kang, Yuejun, Kausalya, Jaya P., Ong, Alicia Ghia Min, Hunziker, Walter, Chung, Jaehoon
Published in Sensors and actuators. B, Chemical (05.07.2015)
Published in Sensors and actuators. B, Chemical (05.07.2015)
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Journal Article
Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16
Kausalya, P Jaya, Amasheh, Salah, Günzel, Dorothee, Wurps, Henrik, Müller, Dominik, Fromm, Michael, Hunziker, Walter
Published in The Journal of clinical investigation (01.04.2006)
Published in The Journal of clinical investigation (01.04.2006)
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Journal Article
ZO-1 Regulates Erk, Smad1/5/8, Smad2, and RhoA Activities to Modulate Self-Renewal and Differentiation of Mouse Embryonic Stem Cells
Xu, Jianliang, Lim, Sophia Beng Hui, Ng, Mei Yong, Ali, Safiah Mohamed, Kausalya, Jaya P., Limviphuvadh, Vachiranee, Maurer-Stroh, Sebastian, Hunziker, Walter
Published in Stem cells (Dayton, Ohio) (01.09.2012)
Published in Stem cells (Dayton, Ohio) (01.09.2012)
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Journal Article
A Novel Claudin 16 Mutation Associated with Childhood Hypercalciuria Abolishes Binding to ZO-1 and Results in Lysosomal Mistargeting
Müller, Dominik, Kausalya, P. Jaya, Claverie-Martin, Felix, Meij, Iwan C., Eggert, Paul, Garcia-Nieto, Victor, Hunziker, Walter
Published in American journal of human genetics (01.12.2003)
Published in American journal of human genetics (01.12.2003)
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Journal Article
Association of ARVCF with zonula occludens (ZO)-1 and ZO-2: binding to PDZ-domain proteins and cell-cell adhesion regulate plasma membrane and nuclear localization of ARVCF
Kausalya, P Jaya, Phua, Dominic C Y, Hunziker, Walter
Published in Molecular biology of the cell (01.12.2004)
Published in Molecular biology of the cell (01.12.2004)
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Journal Article
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: blocking endocytosis restores surface expression of a novel Claudin-16 mutant that lacks the entire C-terminal cytosolic tail
Müller, Dominik, Kausalya, P. Jaya, Meij, Iwan C., Hunziker, Walter
Published in Human molecular genetics (01.04.2006)
Published in Human molecular genetics (01.04.2006)
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Journal Article
Probing effects of pH change on dynamic response of Claudin-2 mediated adhesion using single molecule force spectroscopy
Lim, Tong Seng, Vedula, Sri Ram Krishna, Hui, Shi, Kausalya, P. Jaya, Hunziker, Walter, Lim, Chwee Teck
Published in Experimental cell research (15.08.2008)
Published in Experimental cell research (15.08.2008)
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Journal Article
Molecular force spectroscopy of homophilic nectin-1 interactions
Vedula, Sri Ram Krishna, Lim, Tong Seng, Hui, Shi, Kausalya, P. Jaya, Lane, E. Birgitte, Rajagopal, Gunaretnam, Hunziker, Walter, Lim, Chwee Teck
Published in Biochemical and biophysical research communications (03.11.2007)
Published in Biochemical and biophysical research communications (03.11.2007)
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Journal Article
Methods to analyze subcellular localization and intracellular trafficking of Claudin-16
Kausalya, P Jaya, Hunziker, Walter
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
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Journal Article
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease
Lu, Hao, Rondón Galeano, Maria C, Ott, Elisabeth, Kaeslin, Geraldine, Kausalya, P Jaya, Kramer, Carina, Ortiz-Brüchle, Nadina, Hilger, Nadescha, Metzis, Vicki, Hiersche, Milan, Tay, Shang Yew, Tunningley, Robert, Vij, Shubha, Courtney, Andrew D, Whittle, Belinda, Wühl, Elke, Vester, Udo, Hartleben, Björn, Neuber, Steffen, Frank, Valeska, Little, Melissa H, Epting, Daniel, Papathanasiou, Peter, Perkins, Andrew C, Wright, Graham D, Hunziker, Walter, Gee, Heon Yung, Otto, Edgar A, Zerres, Klaus, Hildebrandt, Friedhelm, Roy, Sudipto, Wicking, Carol, Bergmann, Carsten
Published in Nature genetics (01.07.2017)
Published in Nature genetics (01.07.2017)
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Journal Article