The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism
Kauppi, Björn, Jakob, Clarissa, Färnegårdh, Mathias, Yang, Jie, Ahola, Harri, Alarcon, Maria, Calles, Karin, Engström, Owe, Harlan, John, Muchmore, Steven, Ramqvist, Anna-Karin, Thorell, Susanne, Ohman, Lars, Greer, Jonathan, Gustafsson, Jan-Ake, Carlstedt-Duke, Jan, Carlquist, Mats
Published in The Journal of biological chemistry (20.06.2003)
Published in The Journal of biological chemistry (20.06.2003)
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Journal Article
Structure of an aromatic-ring-hydroxylating dioxygenase – naphthalene 1,2-dioxygenase
Kauppi, Björn, Lee, Kyoung, Carredano, Enrique, Parales, Rebecca E, Gibson, David T, Eklund, Hans, Ramaswamy, S
Published in Structure (London) (15.05.1998)
Published in Structure (London) (15.05.1998)
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Journal Article
The antagonistic crystal structure of the glucocorticoid receptor, ligand-binding domain
Kauppi, B., Jakob, C., Farnegardh, M., Ahola, H., Alarcon, M., Calles, K., Engstrom, O., Harlan, J., Ramkvist, A.-K., Thorell, S., Young, J., Ohman, L., Greer, J., Gustafsson, J.-A., Carlstedt-Duke, J., Carlquist, M.
Published in Acta crystallographica. Section A, Foundations of crystallography (06.08.2002)
Published in Acta crystallographica. Section A, Foundations of crystallography (06.08.2002)
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Journal Article
Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding
Carredano, E, Karlsson, A, Kauppi, B, Choudhury, D, Parales, R E, Parales, J V, Lee, K, Gibson, D T, Eklund, H, Ramaswamy, S
Published in Journal of molecular biology (18.02.2000)
Published in Journal of molecular biology (18.02.2000)
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Journal Article
Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes
von Geldern, Thomas W, Tu, Noah, Kym, Philip R, Link, James T, Jae, Hwan-Soo, Lai, Chunqiu, Apelqvist, Theresa, Rhonnstad, Patrik, Hagberg, Lars, Koehler, Konrad, Grynfarb, Marlena, Goos-Nilsson, Annika, Sandberg, Johnny, Österlund, Marie, Barkhem, Tomas, Höglund, Marie, Wang, Jiahong, Fung, Steven, Wilcox, Denise, Nguyen, Phong, Jakob, Clarissa, Hutchins, Charles, Färnegårdh, Mathias, Kauppi, Björn, Öhman, Lars, Jacobson, Peer B
Published in Journal of medicinal chemistry (12.08.2004)
Published in Journal of medicinal chemistry (12.08.2004)
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Journal Article
The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2
Kauppi, B, Nielsen, B B, Ramaswamy, S, Larsen, I K, Thelander, M, Thelander, L, Eklund, H
Published in Journal of molecular biology (11.10.1996)
Published in Journal of molecular biology (11.10.1996)
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Journal Article
Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes
von Geldern, Thomas W, Tu, Noah, Kym, Philip R, Link, James T, Jae, Hwan-Soo, Lai, Chunqiu, Apelqvist, Theresa, Rhonnstad, Patrik, Hagberg, Lars, Koehler, Konrad, Grynfarb, Marlena, Goos-Nilsson, Annika, Sandberg, Johnny, Österlund, Marie, Barkhem, Tomas, Höglund, Marie, Wang, Jiahong, Fung, Steven, Wilcox, Denise, Nguyen, Phong, Jakob, Clarissa, Hutchins, Charles, Färnegårdh, Mathias, Kauppi, Björn, Öhman, Lars, Jacobson, Peer B
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
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Journal Article
Purification and Crystallization of the Oxygenase Component of Naphthalene Dioxygenase in Native and Selenomethionine-Derivatized Forms
Lee, Kyoung, Kauppi, Björn, Parales, Rebecca E., Gibson, David T., Ramaswamy, S.
Published in Biochemical and biophysical research communications (18.12.1997)
Published in Biochemical and biophysical research communications (18.12.1997)
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Journal Article
The irreversible inactivation of ribonucleotide reductase from Escherichia coli by superoxide radicals
Gaudu, Philippe, Nivière, Vincent, Pétillot, Yves, Kauppi, Björn, Fontecave, Marc
Published in FEBS letters (03.06.1996)
Published in FEBS letters (03.06.1996)
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Journal Article
Reactivity of the tyrosyl radical of Escherichia coli ribonucleotide reductase -- control by the protein
Gerez, C, Elleingand, E, Kauppi, B, Eklund, H, Fontecave, M
Published in European journal of biochemistry (15.10.1997)
Published in European journal of biochemistry (15.10.1997)
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