Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Arceo, Rommel, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.
Published in Cell reports (Cambridge) (28.01.2020)
Published in Cell reports (Cambridge) (28.01.2020)
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Journal Article
Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy
Tom, Irene, Pham, Victoria C., Katschke, Kenneth J., Li, Wei, Liang, Wei-Ching, Gutierrez, Johnny, Young, Andrew Ah, Figueroa, Isabel, Eshghi, Shadi Toghi, Lee, ChingWei V., Kanodia, Jitendra, Snipas, Scott J., Salvesen, Guy S., Lai, Phillip, Honigberg, Lee, van Lookeren Campagne, Menno, Kirchhofer, Daniel, Baruch, Amos, Lill, Jennie R.
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2020)
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Journal Article
IL-33 amplifies an innate immune response in the degenerating retina
Xi, Hongkang, Katschke, Jr, Kenneth J, Li, Yun, Truong, Tom, Lee, Wyne P, Diehl, Lauri, Rangell, Linda, Tao, Jianhua, Arceo, Rommel, Eastham-Anderson, Jeffrey, Hackney, Jason A, Iglesias, Antonio, Cote-Sierra, Javier, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Published in The Journal of experimental medicine (08.02.2016)
Published in The Journal of experimental medicine (08.02.2016)
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Journal Article
Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration
Orozco, Luz D., Chen, Hsu-Hsin, Cox, Christian, Katschke, Kenneth J., Rommel Arceo, Espiritu, Carmina, Caplazi, Patrick, Nghiem, Sarajane Saturnio, Chen, Ying-Jiun, Modrusan, Zora, Dressen, Amy, Goldstein, Leonard D., Clarke, Christine, Bhangale, Tushar, Yaspan, Brian, Jeanne, Marion, Townsend, Michael J., van Lookeren Campagne, Menno, Hackney, Jason A.
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Journal Article
Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy
Katschke, Jr, Kenneth J, Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P, McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Published in Scientific reports (09.05.2018)
Published in Scientific reports (09.05.2018)
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Journal Article
CRIg mediates early Kupffer cell responses to adenovirus
He, Jeannie Q., Katschke, Kenneth J., Gribling, Peter, Suto, Eric, Lee, Wyne P., Diehl, Lauri, Eastham‐Anderson, Jeffrey, Ponakala, Anusha, Komuves, Laszlo, Egen, Jackson G., Lookeren Campagne, Menno
Published in Journal of leukocyte biology (01.02.2013)
Published in Journal of leukocyte biology (01.02.2013)
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Journal Article
Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily
Wang, Xiaoxu, Van Lookeren Campagne, Menno, Katschke, Jr, Kenneth J, Gullipalli, Damodar, Miwa, Takashi, Ueda, Yoshiyasu, Wang, Yuan, Palmer, Matthew, Xing, Guolan, Song, Wen-Chao
Published in Journal of the American Society of Nephrology (01.08.2018)
Published in Journal of the American Society of Nephrology (01.08.2018)
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Journal Article
Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
Katschke, Kenneth J., Stawicki, Scott, Yin, Jianping, Steffek, Micah, Xi, Hongkang, Sturgeon, Lizette, Hass, Philip E., Loyet, Kelly M., DeForge, Laura, Wu, Yan, van Lookeren Campagne, Menno, Wiesmann, Christian
Published in The Journal of biological chemistry (17.04.2009)
Published in The Journal of biological chemistry (17.04.2009)
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Journal Article
Complement Receptor of the Ig Superfamily Enhances Complement-Mediated Phagocytosis in a Subpopulation of Tissue Resident Macrophages
Gorgani, Nick N, He, Jeannie Q, Katschke, Kenneth J., Jr, Helmy, Karim Y, Xi, Hongkang, Steffek, Micah, Hass, Philip E, van Lookeren Campagne, Menno
Published in The Journal of immunology (1950) (01.12.2008)
Published in The Journal of immunology (1950) (01.12.2008)
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Journal Article
Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite
Katschke, Kenneth J., Wu, Ping, Ganesan, Rajkumar, Kelley, Robert F., Mathieu, Mary A., Hass, Philip E., Murray, Jeremy, Kirchhofer, Daniel, Wiesmann, Christian, van Lookeren Campagne, Menno
Published in The Journal of biological chemistry (13.04.2012)
Published in The Journal of biological chemistry (13.04.2012)
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Journal Article
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1
Xi, Hongkang, Katschke, Jr, Kenneth J, Helmy, Karim Y, Wark, Paige A, Kljavin, Noelyn, Clark, Hilary, Eastham-Anderson, Jeffrey, Shek, Theresa, Roose-Girma, Merone, Ghilardi, Nico, van Lookeren Campagne, Menno
Published in The Journal of experimental medicine (18.01.2010)
Published in The Journal of experimental medicine (18.01.2010)
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Journal Article
Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration
Loyet, Kelly M, Deforge, Laura E, Katschke, Jr, Kenneth J, Diehl, Lauri, Graham, Robert R, Pao, Lily, Sturgeon, Lizette, Lewin-Koh, Sock-Cheng, Hollyfield, Joe G, van Lookeren Campagne, Menno
Published in Investigative ophthalmology & visual science (25.09.2012)
Published in Investigative ophthalmology & visual science (25.09.2012)
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Journal Article
Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy
Katschke, Jr, Kenneth J, Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P, McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Published in Scientific reports (24.08.2018)
Published in Scientific reports (24.08.2018)
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Journal Article
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
Katschke, Jr, Kenneth J, Helmy, Karim Y, Steffek, Micah, Xi, Hongkang, Yin, Jianping, Lee, Wyne P, Gribling, Peter, Barck, Kai H, Carano, Richard A D, Taylor, Robin E, Rangell, Linda, Diehl, Lauri, Hass, Philip E, Wiesmann, Christian, van Lookeren Campagne, Menno
Published in The Journal of experimental medicine (11.06.2007)
Published in The Journal of experimental medicine (11.06.2007)
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Journal Article
IL-4 Adenoviral Gene Therapy Reduces Inflammation, Proinflammatory Cytokines, Vascularization, and Bony Destruction in Rat Adjuvant-Induced Arthritis
Woods, James M, Katschke, Kenneth J., Jr, Volin, Michael V, Ruth, Jeffrey H, Woodruff, Drew C, Amin, M. Asif, Connors, Matthew A, Kurata, Hirokazu, Arai, Ken-Ichi, Haines, G. Kenneth, III, Kumar, Pawan, Koch, Alisa E
Published in The Journal of immunology (1950) (15.01.2001)
Published in The Journal of immunology (1950) (15.01.2001)
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Journal Article
A Novel Function for a Glucose Analog of Blood Group H Antigen as a Mediator of Leukocyte-Endothelial Adhesion via Intracellular Adhesion Molecule 1
Zhu, Kui, Amin, M. Asif, Kim, Michael J., Katschke, Kenneth J., Park, Christy C., Koch, Alisa E.
Published in The Journal of biological chemistry (13.06.2003)
Published in The Journal of biological chemistry (13.06.2003)
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Journal Article
Structure of C3b in complex with CRIg gives insights into regulation of complement activation
Fairbrother, Wayne J, Katschke, Kenneth J, Yin, JianPing, DeForge, Laura, McCallum, Scott A, Helmy, Karim Y, Wiesmann, Christian, Embuscado, Lizette, Hass, Philip E, van Lookeren Campagne, Menno, Steffek, Micah
Published in Nature (09.11.2006)
Published in Nature (09.11.2006)
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Journal Article
The trimeric serine protease HtrA1 forms a cage-like inhibition complex with an anti-HtrA1 antibody
Ciferri, Claudio, Lipari, Michael T, Liang, Wei-Ching, Estevez, Alberto, Hang, Julie, Stawicki, Scott, Wu, Yan, Moran, Paul, Elliott, Mike, Eigenbrot, Charles, Katschke, Kenneth J, van Lookeren Campagne, Menno, Kirchhofer, Daniel
Published in Biochemical journal (01.12.2015)
Published in Biochemical journal (01.12.2015)
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Journal Article
Interleukin-13 gene therapy reduces inflammation, vascularization, and bony destruction in rat adjuvant-induced arthritis
Woods, James M, Amin, M Asif, Katschke, Jr, Kenneth J, Volin, Michael V, Ruth, Jeffrey H, Connors, Matthew A, Woodruff, Drew C, Kurata, Hirokazu, Arai, Ken-Ichi, Haines, 3rd, G Kenneth, Kumar, Pawan, Koch, Alisa E
Published in Human gene therapy (10.02.2002)
Published in Human gene therapy (10.02.2002)
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Journal Article
Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis
Katschke, Kenneth J., Rottman, James B., Ruth, Jeffrey H., Qin, Shixin, Wu, Lijun, LaRosa, Gregory, Ponath, Paul, Park, Christy C., Pope, Richard M., Koch, Alisa E.
Published in Arthritis and rheumatism (01.05.2001)
Published in Arthritis and rheumatism (01.05.2001)
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Journal Article