Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
Frega, Monica, Linda, Katrin, Keller, Jason M., Gümüş-Akay, Güvem, Mossink, Britt, van Rhijn, Jon-Ruben, Negwer, Moritz, Klein Gunnewiek, Teun, Foreman, Katharina, Kompier, Nine, Schoenmaker, Chantal, van den Akker, Willem, van der Werf, Ilse, Oudakker, Astrid, Zhou, Huiqing, Kleefstra, Tjitske, Schubert, Dirk, van Bokhoven, Hans, Nadif Kasri, Nael
Published in Nature communications (30.10.2019)
Published in Nature communications (30.10.2019)
Get full text
Journal Article
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks
Mossink, Britt, van Rhijn, Jon-Ruben, Wang, Shan, Linda, Katrin, Vitale, Maria R., Zöller, Johanna E. M., van Hugte, Eline J. H., Bak, Jitske, Verboven, Anouk H. A., Selten, Martijn, Negwer, Moritz, Latour, Brooke L., van der Werf, Ilse, Keller, Jason M., Klein Gunnewiek, Teun M., Schoenmaker, Chantal, Oudakker, Astrid, Anania, Alessia, Jansen, Sophie, Lesch, Klaus-Peter, Frega, Monica, van Bokhoven, Hans, Schubert, Dirk, Nadif Kasri, Nael
Published in Molecular psychiatry (01.01.2022)
Published in Molecular psychiatry (01.01.2022)
Get full text
Journal Article
Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays
Frega, Monica, van Gestel, Sebastianus H C, Linda, Katrin, van der Raadt, Jori, Keller, Jason, Van Rhijn, Jon-Ruben, Schubert, Dirk, Albers, Cornelis A, Nadif Kasri, Nael
Published in Journal of visualized experiments (08.01.2017)
Published in Journal of visualized experiments (08.01.2017)
Get full text
Journal Article
Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype
Frega, Monica, Selten, Martijn, Mossink, Britt, Keller, Jason M., Linda, Katrin, Moerschen, Rebecca, Qu, Jieqiong, Koerner, Pierre, Jansen, Sophie, Oudakker, Astrid, Kleefstra, Tjitske, van Bokhoven, Hans, Zhou, Huiqing, Schubert, Dirk, Nadif Kasri, Nael
Published in Cell reports (Cambridge) (07.01.2020)
Published in Cell reports (Cambridge) (07.01.2020)
Get full text
Journal Article
m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity
Klein Gunnewiek, Teun M., Van Hugte, Eline J.H., Frega, Monica, Guardia, Gemma Solé, Foreman, Katharina, Panneman, Daan, Mossink, Britt, Linda, Katrin, Keller, Jason M., Schubert, Dirk, Cassiman, David, Rodenburg, Richard, Vidal Folch, Noemi, Oglesbee, Devin, Perales-Clemente, Ester, Nelson, Timothy J., Morava, Eva, Nadif Kasri, Nael, Kozicz, Tamas
Published in Cell reports (Cambridge) (21.04.2020)
Published in Cell reports (Cambridge) (21.04.2020)
Get full text
Journal Article
Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition
Arbogast, Thomas, Iacono, Giovanni, Chevalier, Claire, Afinowi, Nurudeen O, Houbaert, Xander, van Eede, Matthijs C, Laliberte, Christine, Birling, Marie-Christine, Linda, Katrin, Meziane, Hamid, Selloum, Mohammed, Sorg, Tania, Nadif Kasri, Nael, Koolen, David A, Stunnenberg, Henk G, Henkelman, R Mark, Kopanitsa, Maksym, Humeau, Yann, De Vries, Bert B A, Herault, Yann
Published in PLoS genetics (13.07.2017)
Published in PLoS genetics (13.07.2017)
Get full text
Journal Article
Biallelic variants in TMEM222 cause a new autosomal recessive neurodevelopmental disorder
Polla, Daniel L., Farazi Fard, Mohammad Ali, Tabatabaei, Zahra, Habibzadeh, Parham, Levchenko, Olga A., Nikuei, Pooneh, Makrythanasis, Periklis, Hussain, Mureed, von Hardenberg, Sandra, Zeinali, Sirous, Fallah, Mohammad-Sadegh, Schuurs-Hoeijmakers, Janneke H.M., Shahzad, Mohsin, Fatima, Fareeha, Fatima, Neelam, Kaat, Laura Donker, Bruggenwirth, Hennie T., Fleming, Leah R., Condie, John, Ploski, Rafal, Pollak, Agnieszka, Pilch, Jacek, Demina, Nina A., Chukhrova, Alena L., Sergeeva, Vasilina S., Venselaar, Hanka, Masri, Amira T., Hamamy, Hanan, Santoni, Federico A., Linda, Katrin, Ahmed, Zubair M., Nadif Kasri, Nael, de Brouwer, Arjan P.M., Bergmann, Anke K., Hethey, Sven, Yavarian, Majid, Ansar, Muhammad, Riazuddin, Saima, Riazuddin, Sheikh, Silawi, Mohammad, Ruggeri, Gaia, Pirozzi, Filomena, Eftekhar, Ebrahim, Taghipour Sheshdeh, Afsaneh, Bahramjahan, Shima, Mirzaa, Ghayda M., Lavrov, Alexander V., Antonarakis, Stylianos E., Faghihi, Mohammad Ali, van Bokhoven, Hans
Published in Genetics in medicine (01.07.2021)
Published in Genetics in medicine (01.07.2021)
Get full text
Journal Article
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders
Linda, Katrin, Lewerissa, Elly I., Verboven, Anouk H. A., Gabriele, Michele, Frega, Monica, Klein Gunnewiek, Teun M., Devilee, Lynn, Ulferts, Edda, Hommersom, Marina, Oudakker, Astrid, Schoenmaker, Chantal, van Bokhoven, Hans, Schubert, Dirk, Testa, Giuseppe, Koolen, David A., de Vries, Bert B.A., Nadif Kasri, Nael
Published in Autophagy (01.02.2022)
Published in Autophagy (01.02.2022)
Get full text
Journal Article
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro
Mossink, Britt, Verboven, Anouk H.A., van Hugte, Eline J.H., Klein Gunnewiek, Teun M., Parodi, Giulia, Linda, Katrin, Schoenmaker, Chantal, Kleefstra, Tjitske, Kozicz, Tamas, van Bokhoven, Hans, Schubert, Dirk, Nadif Kasri, Nael, Frega, Monica
Published in Stem cell reports (14.09.2021)
Published in Stem cell reports (14.09.2021)
Get full text
Journal Article
The Koolen-de Vries syndrome: a phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant
Koolen, David A, Pfundt, Rolph, Linda, Katrin, Beunders, Gea, Veenstra-Knol, Hermine E, Conta, Jessie H, Fortuna, Ana Maria, Gillessen-Kaesbach, Gabriele, Dugan, Sarah, Halbach, Sara, Abdul-Rahman, Omar A, Winesett, Heather M, Chung, Wendy K, Dalton, Marguerite, Dimova, Petia S, Mattina, Teresa, Prescott, Katrina, Zhang, Hui Z, Saal, Howard M, Hehir-Kwa, Jayne Y, Willemsen, Marjolein H, Ockeloen, Charlotte W, Jongmans, Marjolijn C, Van der Aa, Nathalie, Failla, Pinella, Barone, Concetta, Avola, Emanuela, Brooks, Alice S, Kant, Sarina G, Gerkes, Erica H, Firth, Helen V, Õunap, Katrin, Bird, Lynne M, Masser-Frye, Diane, Friedman, Jennifer R, Sokunbi, Modupe A, Dixit, Abhijit, Splitt, Miranda, Kukolich, Mary K, McGaughran, Julie, Coe, Bradley P, Flórez, Jesús, Nadif Kasri, Nael, Brunner, Han G, Thompson, Elizabeth M, Gecz, Jozef, Romano, Corrado, Eichler, Evan E, de Vries, Bert B A
Published in European journal of human genetics : EJHG (01.05.2016)
Published in European journal of human genetics : EJHG (01.05.2016)
Get full text
Journal Article
Added effects of dexamethasone and mesenchymal stem cells on early Natural Killer cell activation
Michelo, Clive M, Fasse, Esther, van Cranenbroek, Bram, Linda, Katrin, van der Meer, Arnold, Abdelrazik, Heba, Joosten, Irma
Published in Transplant immunology (01.07.2016)
Published in Transplant immunology (01.07.2016)
Get full text
Journal Article
Neurons derived from induced pluripotent stem cells on microelectrode arrays: a human model for neurodevelopmental disorders
Frega, Monica, Linda, Katrin, Mossink, Britt, Van Rhijn, Jon-Ruben, Keller, Jason, Van Gestel, Sebastian, Schubert, Dirk, Nadif Kasri, Nael
Published in Frontiers in cellular neuroscience (2018)
Published in Frontiers in cellular neuroscience (2018)
Get full text
Journal Article
Cell-type specific contribution to neuronal network (dys)function in neurodevelopmental disorders
Mossink, Britt, Frega, Monica, Van Rhijn, Jon-Ruben, Linda, Katrin, Schoenmaker, Chantal, Keller, Jason, Janssen, Sophie, Nadif Kasri, Nael, Schubert, Dirk
Published in Frontiers in cellular neuroscience (2018)
Published in Frontiers in cellular neuroscience (2018)
Get full text
Journal Article
Rapid Neuronal Differentiation of Induced Pluripotent Stem Cells for Measuring Network Activity on Micro-electrode Arrays
Frega, Monica, van Gestel, Sebastianus H. C., Linda, Katrin, van der Raadt, Jori, Keller, Jason, Van Rhijn, Jon-Ruben, Schubert, Dirk, Albers, Cornelis A., Nadif Kasri, Nael
Published in Journal of visualized experiments (08.01.2017)
Published in Journal of visualized experiments (08.01.2017)
Get full text
Journal Article