Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
Varma, Vijay R, Oommen, Anup M, Varma, Sudhir, Casanova, Ramon, An, Yang, Andrews, Ryan M, O'Brien, Richard, Pletnikova, Olga, Troncoso, Juan C, Toledo, Jon, Baillie, Rebecca, Arnold, Matthias, Kastenmueller, Gabi, Nho, Kwangsik, Doraiswamy, P Murali, Saykin, Andrew J, Kaddurah-Daouk, Rima, Legido-Quigley, Cristina, Thambisetty, Madhav
Published in PLoS medicine (25.01.2018)
Published in PLoS medicine (25.01.2018)
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Journal Article
Genetics of human metabolism: an update
Kastenmüller, Gabi, Raffler, Johannes, Gieger, Christian, Suhre, Karsten
Published in Human molecular genetics (15.10.2015)
Published in Human molecular genetics (15.10.2015)
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Journal Article
Multi-omics integration in biomedical research – A metabolomics-centric review
Wörheide, Maria A., Krumsiek, Jan, Kastenmüller, Gabi, Arnold, Matthias
Published in Analytica chimica acta (02.01.2021)
Published in Analytica chimica acta (02.01.2021)
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Journal Article
SNiPA: an interactive, genetic variant-centered annotation browser
Arnold, Matthias, Raffler, Johannes, Pfeufer, Arne, Suhre, Karsten, Kastenmüller, Gabi
Published in Bioinformatics (15.04.2015)
Published in Bioinformatics (15.04.2015)
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Journal Article
Biochemical insights from population studies with genetics and metabolomics
Suhre, Karsten, Raffler, Johannes, Kastenmüller, Gabi
Published in Archives of biochemistry and biophysics (01.01.2016)
Published in Archives of biochemistry and biophysics (01.01.2016)
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Journal Article
Integration of ‘omics’ data in aging research: from biomarkers to systems biology
Zierer, Jonas, Menni, Cristina, Kastenmüller, Gabi, Spector, Tim D.
Published in Aging cell (01.12.2015)
Published in Aging cell (01.12.2015)
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Journal Article
Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension
Chouvarine, Philippe, Giera, Martin, Kastenmüller, Gabi, Artati, Anna, Adamski, Jerzy, Bertram, Harald, Hansmann, Georg
Published in Heart (British Cardiac Society) (01.09.2020)
Published in Heart (British Cardiac Society) (01.09.2020)
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Journal Article
The fecal metabolome as a functional readout of the gut microbiome
Zierer, Jonas, Jackson, Matthew A., Kastenmüller, Gabi, Mangino, Massimo, Long, Tao, Telenti, Amalio, Mohney, Robert P., Small, Kerrin S., Bell, Jordana T., Steves, Claire J., Valdes, Ana M., Spector, Tim D., Menni, Cristina
Published in Nature genetics (01.06.2018)
Published in Nature genetics (01.06.2018)
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Journal Article
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity
Pietzner, Maik, Stewart, Isobel D., Raffler, Johannes, Khaw, Kay-Tee, Michelotti, Gregory A., Kastenmüller, Gabi, Wareham, Nicholas J., Langenberg, Claudia
Published in Nature medicine (01.03.2021)
Published in Nature medicine (01.03.2021)
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Journal Article
Mapping the proteo-genomic convergence of human diseases
Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Cortes, Adrian, Koprulu, Mine, Wörheide, Maria A, Oerton, Erin, Cook, James, Stewart, Isobel D, Kerrison, Nicola D, Luan, Jian'an, Raffler, Johannes, Arnold, Matthias, Arlt, Wiebke, O'Rahilly, Stephen, Kastenmüller, Gabi, Gamazon, Eric R, Hingorani, Aroon D, Scott, Robert A, Wareham, Nicholas J, Langenberg, Claudia
Published in Science (American Association for the Advancement of Science) (12.11.2021)
Published in Science (American Association for the Advancement of Science) (12.11.2021)
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Journal Article
Plasma proteomic associations with genetics and health in the UK Biobank
Sun, Benjamin B., Chiou, Joshua, Traylor, Matthew, Benner, Christian, Hsu, Yi-Hsiang, Richardson, Tom G., Surendran, Praveen, Mahajan, Anubha, Robins, Chloe, Vasquez-Grinnell, Steven G., Hou, Liping, Kvikstad, Erika M., Burren, Oliver S., Davitte, Jonathan, Ferber, Kyle L., Gillies, Christopher E., Hedman, Åsa K., Hu, Sile, Lin, Tinchi, Mikkilineni, Rajesh, Pendergrass, Rion K., Pickering, Corran, Prins, Bram, Baird, Denis, Chen, Chia-Yen, Ward, Lucas D., Deaton, Aimee M., Welsh, Samantha, Willis, Carissa M., Lehner, Nick, Arnold, Matthias, Wörheide, Maria A., Suhre, Karsten, Kastenmüller, Gabi, Sethi, Anurag, Cule, Madeleine, Raj, Anil, Burkitt-Gray, Lucy, Melamud, Eugene, Black, Mary Helen, Fauman, Eric B., Howson, Joanna M. M., Kang, Hyun Min, McCarthy, Mark I., Nioi, Paul, Petrovski, Slavé, Scott, Robert A., Smith, Erin N., Szalma, Sándor, Waterworth, Dawn M., Mitnaul, Lyndon J., Szustakowski, Joseph D., Gibson, Bradford W., Miller, Melissa R., Whelan, Christopher D.
Published in Nature (London) (12.10.2023)
Published in Nature (London) (12.10.2023)
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Journal Article
Taurine deficiency as a driver of aging
Singh, Parminder, Gollapalli, Kishore, Mangiola, Stefano, Schranner, Daniela, Yusuf, Mohd Aslam, Chamoli, Manish, Shi, Sting L, Lopes Bastos, Bruno, Nair, Tripti, Riermeier, Annett, Vayndorf, Elena M, Wu, Judy Z, Nilakhe, Aishwarya, Nguyen, Christina Q, Muir, Michael, Kiflezghi, Michael G, Foulger, Anna, Junker, Alex, Devine, Jack, Sharan, Kunal, Chinta, Shankar J, Rajput, Swati, Rane, Anand, Baumert, Philipp, Schönfelder, Martin, Iavarone, Francescopaolo, di Lorenzo, Giorgia, Kumari, Swati, Gupta, Alka, Sarkar, Rajesh, Khyriem, Costerwell, Chawla, Amanpreet S, Sharma, Ankur, Sarper, Nazan, Chattopadhyay, Naibedya, Biswal, Bichitra K, Settembre, Carmine, Nagarajan, Perumal, Targoff, Kimara L, Picard, Martin, Gupta, Sarika, Velagapudi, Vidya, Papenfuss, Anthony T, Kaya, Alaattin, Ferreira, Miguel Godinho, Kennedy, Brian K, Andersen, Julie K, Lithgow, Gordon J, Ali, Abdullah Mahmood, Mukhopadhyay, Arnab, Palotie, Aarno, Kastenmüller, Gabi, Kaeberlein, Matt, Wackerhage, Henning, Pal, Bhupinder, Yadav, Vijay K
Published in Science (American Association for the Advancement of Science) (09.06.2023)
Published in Science (American Association for the Advancement of Science) (09.06.2023)
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Journal Article
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
MahmoudianDehkordi, Siamak, Arnold, Matthias, Nho, Kwangsik, Ahmad, Shahzad, Jia, Wei, Xie, Guoxiang, Louie, Gregory, Kueider-Paisley, Alexandra, Moseley, M. Arthur, Thompson, J. Will, St John Williams, Lisa, Tenenbaum, Jessica D., Blach, Colette, Baillie, Rebecca, Han, Xianlin, Bhattacharyya, Sudeepa, Toledo, Jon B., Schafferer, Simon, Klein, Sebastian, Koal, Therese, Risacher, Shannon L., Kling, Mitchel Allan, Motsinger-Reif, Alison, Rotroff, Daniel M., Jack, John, Hankemeier, Thomas, Bennett, David A., De Jager, Philip L., Trojanowski, John Q., Shaw, Leslie M., Weiner, Michael W., Doraiswamy, P. Murali, van Duijn, Cornelia M., Saykin, Andrew J., Kastenmüller, Gabi, Kaddurah-Daouk, Rima
Published in Alzheimer's & dementia (01.01.2019)
Published in Alzheimer's & dementia (01.01.2019)
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Journal Article
Genetic diagnosis of Mendelian disorders via RNA sequencing
Kremer, Laura S., Bader, Daniel M., Mertes, Christian, Kopajtich, Robert, Pichler, Garwin, Iuso, Arcangela, Haack, Tobias B., Graf, Elisabeth, Schwarzmayr, Thomas, Terrile, Caterina, Koňaříková, Eliška, Repp, Birgit, Kastenmüller, Gabi, Adamski, Jerzy, Lichtner, Peter, Leonhardt, Christoph, Funalot, Benoit, Donati, Alice, Tiranti, Valeria, Lombes, Anne, Jardel, Claude, Gläser, Dieter, Taylor, Robert W., Ghezzi, Daniele, Mayr, Johannes A., Rötig, Agnes, Freisinger, Peter, Distelmaier, Felix, Strom, Tim M., Meitinger, Thomas, Gagneur, Julien, Prokisch, Holger
Published in Nature communications (12.06.2017)
Published in Nature communications (12.06.2017)
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Journal Article
An atlas of genetic influences on human blood metabolites
Shin, So-Youn, Fauman, Eric B, Petersen, Ann-Kristin, Krumsiek, Jan, Santos, Rita, Huang, Jie, Arnold, Matthias, Erte, Idil, Forgetta, Vincenzo, Yang, Tsun-Po, Walter, Klaudia, Menni, Cristina, Chen, Lu, Vasquez, Louella, Valdes, Ana M, Hyde, Craig L, Wang, Vicky, Ziemek, Daniel, Roberts, Phoebe, Xi, Li, Grundberg, Elin, Waldenberger, Melanie, Richards, J Brent, Mohney, Robert P, Milburn, Michael V, John, Sally L, Trimmer, Jeff, Theis, Fabian J, Overington, John P, Suhre, Karsten, Brosnan, M Julia, Gieger, Christian, Kastenmüller, Gabi, Spector, Tim D, Soranzo, Nicole
Published in Nature genetics (01.06.2014)
Published in Nature genetics (01.06.2014)
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Journal Article
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
Deelen, Joris, Kettunen, Johannes, Fischer, Krista, van der Spek, Ashley, Trompet, Stella, Kastenmüller, Gabi, Boyd, Andy, Zierer, Jonas, van den Akker, Erik B., Ala-Korpela, Mika, Amin, Najaf, Demirkan, Ayse, Ghanbari, Mohsen, van Heemst, Diana, Ikram, M. Arfan, van Klinken, Jan Bert, Mooijaart, Simon P., Peters, Annette, Salomaa, Veikko, Sattar, Naveed, Spector, Tim D., Tiemeier, Henning, Verhoeven, Aswin, Waldenberger, Melanie, Würtz, Peter, Davey Smith, George, Metspalu, Andres, Perola, Markus, Menni, Cristina, Geleijnse, Johanna M., Drenos, Fotios, Beekman, Marian, Jukema, J. Wouter, van Duijn, Cornelia M., Slagboom, P. Eline
Published in Nature communications (20.08.2019)
Published in Nature communications (20.08.2019)
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Journal Article
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals
Amin, Najaf, Liu, Jun, Bonnechere, Bruno, MahmoudianDehkordi, Siamak, Arnold, Matthias, Batra, Richa, Chiou, Yu-Jie, Fernandes, Marco, Ikram, M Arfan, Kraaij, Robert, Krumsiek, Jan, Newby, Danielle, Nho, Kwangsik, Radjabzadeh, Djawad, Saykin, Andrew J, Shi, Liu, Sproviero, William, Winchester, Laura, Yang, Yang, Nevado-Holgado, Alejo J, Kastenmüller, Gabi, Kaddurah-Daouk, Rima, van Duijn, Cornelia M
Published in JAMA psychiatry (Chicago, Ill.) (01.06.2023)
Published in JAMA psychiatry (Chicago, Ill.) (01.06.2023)
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Journal Article
Metabolomics enables precision medicine: “A White Paper, Community Perspective”
Beger, Richard D., Dunn, Warwick, Schmidt, Michael A., Gross, Steven S., Kirwan, Jennifer A., Cascante, Marta, Brennan, Lorraine, Wishart, David S., Oresic, Matej, Hankemeier, Thomas, Broadhurst, David I., Lane, Andrew N., Suhre, Karsten, Kastenmüller, Gabi, Sumner, Susan J., Thiele, Ines, Fiehn, Oliver, Kaddurah-Daouk, Rima
Published in Metabolomics (2016)
Published in Metabolomics (2016)
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Journal Article
Metabolite Concentration Changes in Humans After a Bout of Exercise: a Systematic Review of Exercise Metabolomics Studies
Schranner, Daniela, Kastenmüller, Gabi, Schönfelder, Martin, Römisch-Margl, Werner, Wackerhage, Henning
Published in Sports medicine - open (10.02.2020)
Published in Sports medicine - open (10.02.2020)
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Journal Article
A cross-platform approach identifies genetic regulators of human metabolism and health
Lotta, Luca A., Pietzner, Maik, Stewart, Isobel D., Wittemans, Laura B. L., Li, Chen, Bonelli, Roberto, Raffler, Johannes, Biggs, Emma K., Oliver-Williams, Clare, Auyeung, Victoria P. W., Luan, Jian’an, Wheeler, Eleanor, Paige, Ellie, Surendran, Praveen, Michelotti, Gregory A., Scott, Robert A., Burgess, Stephen, Zuber, Verena, Sanderson, Eleanor, Koulman, Albert, Imamura, Fumiaki, Forouhi, Nita G., Khaw, Kay-Tee, Griffin, Julian L., Wood, Angela M., Kastenmüller, Gabi, Danesh, John, Butterworth, Adam S., Gribble, Fiona M., Reimann, Frank, Bahlo, Melanie, Fauman, Eric, Wareham, Nicholas J., Langenberg, Claudia
Published in Nature genetics (01.01.2021)
Published in Nature genetics (01.01.2021)
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