Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors
Kasteel, E. E. J., Darney, K., Kramer, N. I., Dorne, J. L. C. M., Lautz, L. S.
Published in Archives of toxicology (01.08.2020)
Published in Archives of toxicology (01.08.2020)
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Journal Article
Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics
Kasteel, Emma E. J., Nijmeijer, Sandra M., Darney, Keyvin, Lautz, Leonie S., Dorne, Jean Lou C. M., Kramer, Nynke I., Westerink, Remco H. S.
Published in Archives of toxicology (01.12.2020)
Published in Archives of toxicology (01.12.2020)
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Journal Article
Application of in vitro data in physiologically-based kinetic models for quantitative in vitro-in vivo extrapolation: A case-study for baclofen
Kasteel, Emma E.J., Lautz, Leonie S., Culot, Maxime, Kramer, Nynke I., Zwartsen, Anne
Published in Toxicology in vitro (01.10.2021)
Published in Toxicology in vitro (01.10.2021)
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Journal Article
Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment
Darney, K., Kasteel, E.E.J., Buratti, F.M., Turco, L., Vichi, S., Béchaux, C., Roudot, A.C., Kramer, N.I., Testai, E., Dorne, J.L.C.M., Di Consiglio, E., Lautz, L.S.
Published in Environment international (01.05.2020)
Published in Environment international (01.05.2020)
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Journal Article
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?
Tukker, Anke M, de Groot, Martje W G D M, Wijnolts, Fiona M J, Kasteel, Emma E J, Hondebrink, Laura, Westerink, Remco H S
Published in ALTEX, alternatives to animal experimentation (2016)
Published in ALTEX, alternatives to animal experimentation (2016)
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Journal Article