Differential fates of biomolecules delivered to target cells via extracellular vesicles
Kanada, Masamitsu, Bachmann, Michael H., Hardy, Jonathan W., Frimannson, Daniel Omar, Bronsart, Laura, Wang, Andrew, Sylvester, Matthew D., Schmidt, Tobi L., Kaspar, Roger L., Butte, Manish J., Matin, A. C., Contag, Christopher H.
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
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Keratin 16 regulates innate immunity in response to epidermal barrier breach
Lessard, Juliane C., Piña-Paz, Sylvia, Rotty, Jeremy D., Hickerson, Robyn P., Kaspar, Roger L., Balmain, Allan, Coulombe, Pierre A.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
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In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles
Lobovkina, Tatsiana, Jacobson, Gunilla B, Gonzalez-Gonzalez, Emilio, Hickerson, Robyn P, Leake, Devin, Kaspar, Roger L, Contag, Christopher H, Zare, Richard N
Published in ACS nano (27.12.2011)
Published in ACS nano (27.12.2011)
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Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells
Geihe, Erika I, Cooley, Christina B, Simon, Jeff R, Kiesewetter, Matthew K, Edward, Justin A, Hickerson, Robyn P, Kaspar, Roger L, Hedrick, James L, Waymouth, Robert M, Wender, Paul A
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder
Leachman, Sancy A, Hickerson, Robyn P, Schwartz, Mary E, Bullough, Emily E, Hutcherson, Stephen L, Boucher, Kenneth M, Hansen, C David, Eliason, Mark J, Srivatsa, G Susan, Kornbrust, Douglas J, Smith, Frances JD, McLean, WH Irwin, Milstone, Leonard M, Kaspar, Roger L
Published in Molecular therapy (01.02.2010)
Published in Molecular therapy (01.02.2010)
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Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
Leachman, Sancy A, Hickerson, Robyn P, Hull, Peter R, Smith, Frances J.D, Milstone, Leonard M, Lane, E. Birgitte, Bale, Sherri J, Roop, Dennis R, McLean, W.H. Irwin, Kaspar, Roger L
Published in Journal of dermatological science (01.09.2008)
Published in Journal of dermatological science (01.09.2008)
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Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model
Hickerson, Robyn P., Flores, Manuel A., Leake, Devin, Lara, Maria F., Contag, Christopher H., Leachman, Sancy A., Kaspar, Roger L.
Published in Journal of investigative dermatology (01.05.2011)
Published in Journal of investigative dermatology (01.05.2011)
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Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients
Hickerson, Robyn P, Leake, Devin, Pho, Lana N, Leachman, Sancy A, Kaspar, Roger L
Published in Journal of dermatological science (01.11.2009)
Published in Journal of dermatological science (01.11.2009)
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An appraisal of oral retinoids in the treatment of pachyonychia congenita
Gruber, Robert, MD, Edlinger, Michael, MSc, Kaspar, Roger L., PhD, Hansen, C. David, MD, Leachman, Sancy, MD, PhD, Milstone, Leonard M., MD, Smith, Frances J.D., PhD, Sidoroff, Alexis, MD, Fritsch, Peter O., MD, Schmuth, Matthias, MD
Published in Journal of the American Academy of Dermatology (01.06.2012)
Published in Journal of the American Academy of Dermatology (01.06.2012)
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Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays
Lara, Maria Fernanda, González-González, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Leake, Devin, Milstone, Leonard M, Contag, Christopher H, Kaspar, Roger L
Published in Human gene therapy (01.08.2012)
Published in Human gene therapy (01.08.2012)
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Gene expression profiling in pachyonychia congenita skin
Cao, Yu-An, Hickerson, Robyn P, Seegmiller, Brandon L, Grapov, Dmitry, Gross, Maren M, Bessette, Marc R, Phinney, Brett S, Flores, Manuel A, Speaker, Tycho J, Vermeulen, Annaleen, Bravo, Albert A, Bruckner, Anna L, Milstone, Leonard M, Schwartz, Mary E, Rice, Robert H, Kaspar, Roger L
Published in Journal of dermatological science (01.03.2015)
Published in Journal of dermatological science (01.03.2015)
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Development of Therapeutic siRNAs for Pachyonychia Congenita
Smith, Frances J.D., Hickerson, Robyn P., Sayers, Jane M., Reeves, Robert E., Contag, Christopher H., Leake, Devin, Kaspar, Roger L., Irwin McLean, W.H.
Published in Journal of investigative dermatology (01.01.2008)
Published in Journal of investigative dermatology (01.01.2008)
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Clinical and Pathological Features of Pachyonychia Congenita
Leachman, Sancy A., Kaspar, Roger L., Fleckman, Philip, Florell, Scott R., Smith, Frances J.D., McLean, W.H. Irwin, Lunny, Declan P., Milstone, Leonard M., van Steensel, Maurice A.M., Munro, Colin S., O'Toole, Edel A., Celebi, Julide T., Kansky, Aleksej, Lane, EBirgitte
Published in The Journal of investigative dermatology symposium proceedings (01.10.2005)
Published in The Journal of investigative dermatology symposium proceedings (01.10.2005)
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Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device
Hickerson, Robyn P, Wey, Winston C, Rimm, David L, Speaker, Tycho, Suh, Susie, Flores, Manuel A, Gonzalez-Gonzalez, Emilio, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published in Molecular therapy. Nucleic acids (01.10.2013)
Published in Molecular therapy. Nucleic acids (01.10.2013)
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Assessing delivery and quantifying efficacy of small interfering ribonucleic acid therapeutics in the skin using a dual-axis confocal microscope
Ra, Hyejun, Gonzalez-Gonzalez, Emilio, Smith, Bryan R, Gambhir, Sanjiv S, Kino, Gordon S, Solgaard, Olav, Kaspar, Roger L, Contag, Christopher H
Published in Journal of biomedical optics (01.05.2010)
Published in Journal of biomedical optics (01.05.2010)
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Identification of AUF1 as a rapamycin-responsive binding protein to the 5′-terminal oligopyrimidine element of mRNAs
Kakegawa, Tomohito, Ohuchi, Nozomi, Hayakawa, Akiko, Hirata, Satoru, Matsuda, Megumi, Kogure, Keiko, Kobayashi, Hiroshi, Inoue, Akira, Kaspar, Roger L.
Published in Archives of biochemistry and biophysics (01.09.2007)
Published in Archives of biochemistry and biophysics (01.09.2007)
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Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept
Chong, Rosalind H.E., Gonzalez-Gonzalez, Emilio, Lara, Maria F., Speaker, Tycho J., Contag, Christopher H., Kaspar, Roger L., Coulman, Sion A., Hargest, Rachel, Birchall, James C.
Published in Journal of controlled release (28.03.2013)
Published in Journal of controlled release (28.03.2013)
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Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD)
Gonzalez-Gonzalez, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Spitler, Ryan, Flores, Manuel A, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published in Molecular therapy (01.09.2010)
Published in Molecular therapy (01.09.2010)
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