Beyond Antibodies: The DARPin® Drug Platform
Stumpp, Michael T., Dawson, Keith M., Binz, H. Kaspar
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2020)
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2020)
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Journal Article
Half-life extension using serum albumin-binding DARPin® domains
Steiner, Daniel, Merz, Frieder W, Sonderegger, Ivo, Gulotti-Georgieva, Maya, Villemagne, Denis, Phillips, Douglas J, Forrer, Patrik, Stumpp, Michael T, Zitt, Christof, Binz, H Kaspar
Published in Protein engineering, design and selection (01.09.2017)
Published in Protein engineering, design and selection (01.09.2017)
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Journal Article
DARPins: A new generation of protein therapeutics
Stumpp, Michael T., Binz, H. Kaspar, Amstutz, Patrick
Published in Drug discovery today (01.08.2008)
Published in Drug discovery today (01.08.2008)
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Journal Article
Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size
ZAHND, Christian, KAWE, Martin, PLÜCKTHUN, Andreas, STUMPP, Michael T, DE PASQUALE, Christine, TAMASKOVIC, Rastislav, NAGY-DAVIDESCU, Gabriela, DREIER, Birgit, SCHIBLI, Roger, KASPAR BINZ, H, WAIBEL, Robert
Published in Cancer research (Chicago, Ill.) (15.02.2010)
Published in Cancer research (Chicago, Ill.) (15.02.2010)
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Journal Article
Beyond Antibodies: The DARPin® Drug Platform
Stumpp, Michael T., Dawson, Keith M., Binz, H. Kaspar
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2020)
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.08.2020)
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Journal Article
Folding and Unfolding Mechanism of Highly Stable Full-Consensus Ankyrin Repeat Proteins
Wetzel, Svava K., Settanni, Giovanni, Kenig, Manca, Binz, H. Kaspar, Plückthun, Andreas
Published in Journal of molecular biology (08.02.2008)
Published in Journal of molecular biology (08.02.2008)
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Journal Article
Capture efficiency of artificial food particles of post-settlement juveniles of the Greenshell™ mussel, Perna canaliculus
Gui, Y., Kaspar, H.F., Zamora, L.N., Dunphy, B.J., Jeffs, A.G.
Published in Aquaculture (01.11.2016)
Published in Aquaculture (01.11.2016)
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Journal Article
Design and characterization of MP0250, a tri-specific anti-HGF/anti-VEGF DARPin® drug candidate
Binz, H Kaspar, Bakker, Talitha R, Phillips, Douglas J, Cornelius, Andreas, Zitt, Christof, Göttler, Thomas, Sigrist, Gabriel, Fiedler, Ulrike, Ekawardhani, Savira, Dolado, Ignacio, Saliba, Johan Abram, Tresch, Gaby, Proba, Karl, Stumpp, Michael T
Published in mAbs (17.11.2017)
Published in mAbs (17.11.2017)
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Journal Article
Targeting Extracellular Domains D4 and D7 of Vascular Endothelial Growth Factor Receptor 2 Reveals Allosteric Receptor Regulatory Sites
Hyde, Caroline A. C., Giese, Alexandra, Stuttfeld, Edward, Abram Saliba, Johan, Villemagne, Denis, Schleier, Thomas, Binz, H. Kaspar, Ballmer-Hofer, Kurt
Published in Molecular and Cellular Biology (01.10.2012)
Published in Molecular and Cellular Biology (01.10.2012)
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Journal Article
Designing Repeat Proteins: Well-expressed, Soluble and Stable Proteins from Combinatorial Libraries of Consensus Ankyrin Repeat Proteins
Binz, H.Kaspar, Stumpp, Michael T, Forrer, Patrik, Amstutz, Patrick, Plückthun, Andreas
Published in Journal of molecular biology (12.09.2003)
Published in Journal of molecular biology (12.09.2003)
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Journal Article
Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications
Stahl, Andreas, Stumpp, Michael T., Schlegel, Anja, Ekawardhani, Savira, Lehrling, Christina, Martin, Gottfried, Gulotti-Georgieva, Maya, Villemagne, Denis, Forrer, Patrik, Agostini, Hansjürgen T., Binz, H. Kaspar
Published in Angiogenesis (London) (01.01.2013)
Published in Angiogenesis (London) (01.01.2013)
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Journal Article
Feeding untreated and pasteurized waste milk and bulk milk to calves: effects on calf performance, health status and antibiotic resistance of faecal bacteria
Aust, V., Knappstein, K., Kunz, H.-J., Kaspar, H., Wallmann, J., Kaske, M.
Published in Journal of animal physiology and animal nutrition (01.12.2013)
Published in Journal of animal physiology and animal nutrition (01.12.2013)
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Journal Article
Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism
Schweizer, Andreas, Roschitzki-Voser, Heidi, Amstutz, Patrick, Briand, Christophe, Gulotti-Georgieva, Maya, Prenosil, Eva, Binz, H. Kaspar, Capitani, Guido, Baici, Antonio, Plückthun, Andreas, Grütter, Markus G.
Published in Structure (London) (01.05.2007)
Published in Structure (London) (01.05.2007)
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Journal Article
Intracellular Kinase Inhibitors Selected from Combinatorial Libraries of Designed Ankyrin Repeat Proteins
Amstutz, Patrick, Binz, H. Kaspar, Parizek, Petra, Stumpp, Michael T., Kohl, Andreas, Grütter, Markus G., Forrer, Patrik, Plückthun, Andreas
Published in The Journal of biological chemistry (01.07.2005)
Published in The Journal of biological chemistry (01.07.2005)
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Journal Article
Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate
Popp, F.C, Eggenhofer, E, Renner, P, Slowik, P, Lang, S.A, Kaspar, H, Geissler, E.K, Piso, P, Schlitt, H.J, Dahlke, M.H
Published in Transplant immunology (01.11.2008)
Published in Transplant immunology (01.11.2008)
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Journal Article